利索-全球专利检索

  1. 登录
  2. 注册

搜索结果

20 条记录 (耗时 0.021 秒)

    METHODS AND SYSTEMS FOR EFFICIENT PROCESSING OF BIOLOGICAL SAMPLES
    12.
    发明公开
    METHODS AND SYSTEMS FOR EFFICIENT PROCESSING OF BIOLOGICAL SAMPLES 审中-公开
    方法和系统生物样品的有效处理

    公开(公告)号：EP2625502A4

    公开(公告)日：2014-12-03

    申请号：EP11831630

    申请日：2011-10-06

    申请人： BIOCARE MEDICAL LLC

    发明人： BARKER STEPHEN ,  AVANTSA SARADHA

    IPC分类号： G01N1/31

    CPC分类号： G01N1/31 ,  B01F11/0071 ,  B01F13/0083 ,  G01N1/312 ,  G01N33/54346 ,  G01N33/587 ,  G01N35/0098 ,  Y10T436/25

    摘要： Systems and methods of sample (1) and staining processing including compression and dynamic movement of liquids (3) in a fluidically moving substantially contained liquid bridge (6) perhaps between a hydrophobic wand (4) and a hydrophilic sample support element (2). Embodiments may include low volume reagent and perhaps even low volume buffer wash in sample processing. In addition, antibodies can be conjugated with nanoparticles (64) and can be used in sample processing. Exposing a sample with or without movement to AC, DC, or even a permanent magnet field may improve staining. Staining with nanoparticle reagents could be quantified using a microscope with a magnetometer below the slide viewing area. The detection of nanoparticles attached to the chemistry may facilitate the quantification of cancerous cells stained in the tissue.

    METHODS AND SYSTEMS FOR EFFICIENT PROCESSING OF BIOLOGICAL SAMPLES
    20.
    发明公开
    METHODS AND SYSTEMS FOR EFFICIENT PROCESSING OF BIOLOGICAL SAMPLES 审中-公开
    VERFAHREN UND SYSTEME ZUR EFFIZIENTEN VERARBEITUNG BIOLOGISCHER PROBEN

    公开(公告)号：EP2625502A1

    公开(公告)日：2013-08-14

    申请号：EP11831630.6

    申请日：2011-10-06

    申请人： Biocare Medical, LLC

    发明人： BARKER, Stephen ,  AVANTSA, Saradha

    IPC分类号： G01N1/31

    CPC分类号： G01N1/31 ,  B01F11/0071 ,  B01F13/0083 ,  G01N1/312 ,  G01N33/54346 ,  G01N33/587 ,  G01N35/0098 ,  Y10T436/25

    摘要： Systems and methods of sample (1) and staining processing including compression and dynamic movement of liquids (3) in a fluidically moving substantially contained liquid bridge (6) perhaps between a hydrophobic wand (4) and a hydrophilic sample support element (2). Embodiments may include low volume reagent and perhaps even low volume buffer wash in sample processing. In addition, antibodies can be conjugated with nanoparticles (64) and can be used in sample processing. Exposing a sample with or without movement to AC, DC, or even a permanent magnet field may improve staining. Staining with nanoparticle reagents could be quantified using a microscope with a magnetometer below the slide viewing area. The detection of nanoparticles attached to the chemistry may facilitate the quantification of cancerous cells stained in the tissue.

    摘要翻译： 样品（1）的系统和方法以及染色处理，包括液体（3）在流体运动的基本容纳的液体桥（6）中的压缩和动态运动，可能在疏水棒（4）和亲水样品支撑元件（2）之间。 实施例可以包括样品处理中的低体积试剂和甚至低容量的缓冲液洗涤。 此外，抗体可以与纳米颗粒（64）缀合，并可用于样品处理。 将具有或不具有移动的样品暴露于AC，DC或甚至永久磁场可能会改善染色。 用纳米粒子试剂染色可以用显微镜在载玻片观察区域下方的磁力计量化。 附着于化学物质的纳米颗粒的检测可能有助于定量组织中染色的癌细胞。