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11.发明公开Process and intermediates for the preparation of antitumoral dihydropyran-2-one compounds 审中-公开用于制备抗肿瘤二氢吡喃-2-酮化合物的方法和中间体
公开(公告)号：EP2404913A2
公开(公告)日：2012-01-11
申请号：EP11177479.0
申请日：2007-06-15
申请人： Pharma Mar S.A.
发明人： Martín López, Mª Jesús , Coello Molinero, Laura , Reyes Benítez, José Fernando , Rodríguez Vicente, Alberto , Garranzo GarcÍa-Ibarrola, María , Murcia Pérez, Carmen , Francesch Solloso, Andrés , Sánchez Sancho, Francisco , Cuevas Marchante, María del Carmen , Fernández Rodríguez, Rogelio
IPC分类号： C07D309/32
CPC分类号： C07D309/32
摘要： A process and intermediates for the preparation of a compound of general formula (I), or a pharmaceutically acceptable salt, tautomer, or stereoisomer thereof
摘要翻译： 用于制备通式（I）化合物或其药学上可接受的盐，互变异构体或立体异构体的方法和中间体
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12.发明公开
公开(公告)号：EP2404912A2
公开(公告)日：2012-01-11
申请号：EP11177474.1
申请日：2007-06-15
申请人： Pharma Mar S.A.
发明人： Martín López, Mª Jesús , Coello Molinero, Laura , Reyes Benítez, José Fernando , Rodríguez Vicente, Alberto , Garranzo GarcÍa-Ibarrola, María , Murcia Pérez, Carmen , Francesch Solloso, Andrés , Sánchez Sancho, Francisco , Cuevas Marchante, María del Carmen , Fernández Rodríguez, Rogelio
IPC分类号： C07D309/32
CPC分类号： C07D309/32
摘要： A process and intermediates for the preparation of a compound of general formula (I), or a pharmaceutically acceptable salt, tautomer, or stereoisomer thereof
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公开(公告)号：EP2280026A3
公开(公告)日：2011-05-25
申请号：EP10179442.8
申请日：2004-09-09
申请人： Pharma Mar, S.A.U.
发明人： Fernandez Donis, Ariadna , Giralt Liedó, Ernest , Gracia Cantador, Carolina , López Rodriguez, Pilar , Varon Colomer, Sonia , Cuevas Marchante, Carmen , López Macia, Angel , Francesch Solloso, Andrés , Jiménez Garcia, José-Carlos , Royo Expósito, Miriam , Albericio Palomera, Fernando
摘要： New analogues of kahalalide F are provided.
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公开(公告)号：EP2280026A2
公开(公告)日：2011-02-02
申请号：EP10179442.8
申请日：2004-09-09
申请人： Pharma Mar, S.A.U.
发明人： Fernandez Donis, Ariadna , Giralt Lledó, Ernest , Gracia Cantador, Carolina , López Rodriguez, Pilar , Varon Colomer, Sonia , Cuevas Marchante, Carmen , López Macia, Ángel , Francesch Solloso, Andrés , Jiménez Garcia, José-Carlos , Royo Expósito, Miriam , Albericio Palomera, Fernando
摘要： New analogues of kahalalide F are provided.
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公开(公告)号：EP2280025A2
公开(公告)日：2011-02-02
申请号：EP10179425.3
申请日：2004-09-09
申请人： Pharma Mar, S.A.U.
发明人： Fernandez Donis, Ariadna , Giralt Lledó, Ernest , Gracia Cantador, Carolina , López Rodriguez, Pilar , Varon Colomer, Sonia , Cuevas Marchante, Carmen , López Macia, Ángel , Francesch Solloso, Andrés , Jiménez Garcia, José Carlos , Royo Expósito, Miriam , Albericio Palomera, Fernando
摘要： New analogues of kahalalide F are provided.
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公开(公告)号：EP2597091A1
公开(公告)日：2013-05-29
申请号：EP13154647.5
申请日：2008-12-19
申请人： PHARMA MAR, S.A.
发明人： Rodriguez Vincente, Alberto , Garcia-Lbarrola, Maria Garranzo , Pérez Carmen Murcia , Sancho, Francisco Sánchez , Marchante, Carmen Cuevas , Urbano, Christina Mateo , Juárez, Isabel Digón
IPC分类号： C07D309/10 , C07D309/30 , C07D309/32 , A61K31/351 , A61K31/365
CPC分类号： A61K31/695 , A61K31/351 , A61K31/366 , C07D309/10 , C07D309/30 , C07D309/32 , C07F7/1856 , Y02P20/55
摘要： A compound of general formula (I)
wherein A, Y, W, R 1 , R 2 , R 3 , R 4 , R 5 , and R 6 take various meanings for use in the treatment of cancer.-
17.发明公开ARYLFLUOROPHOSPHATE INHIBITORS OF INTESTINAL APICAL MEMBRANE SODIUM/PHOSPHATE CO-TRANSPORT 有权油酸钠ARYLFLUORPHOSPHATHEMMER /磷酸盐运输局排便顶膜
公开(公告)号：EP2542560A2
公开(公告)日：2013-01-09
申请号：EP11751437.2
申请日：2011-03-04
申请人： Duophos
发明人： PEERCE, Brian , SLOMOWITZ, Larry
IPC分类号： C07F9/14 , C07F9/20 , C07F9/26 , A61K31/683 , A61P9/12
CPC分类号： C07F9/146 , C07F9/1406
摘要： The present invention is directed to fluorophosphates, and pharmaceutical compositions thereof, which are inhibitors of intestinal apical sodium/phosphate co-transport and are useful in the treatment of hyperphosphatemia, in reducing blood phosphate levels, and in treating hypertension.
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18.发明公开Process and intermediates for the preparation of antitumoral dihydropyran-2-one compounds 审中-公开方法和中间体制备二氢吡喃-2-酮抗肿瘤化合物
公开(公告)号：EP2404912A3
公开(公告)日：2012-07-25
申请号：EP11177474.1
申请日：2007-06-15
申请人： Pharma Mar S.A.
发明人： Martín López, Mª Jesús , Coello Molinero, Laura , Reyes Benítez, José Fernando , Rodríguez Vicente, Alberto , Garranzo GarcÍa-Ibarrola, María , Murcia Pérez, Carmen , Francesch Solloso, Andrés , Sánchez Sancho, Francisco , Cuevas Marchante, María del Carmen , Fernández Rodríguez, Rogelio
IPC分类号： C07D309/32
CPC分类号： C07D309/32
摘要： A process and intermediates for the preparation of a compound of general formula (I), or a pharmaceutically acceptable salt, tautomer, or stereoisomer thereof
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19.发明公开
公开(公告)号：EP2404913A3
公开(公告)日：2012-06-06
申请号：EP11177479.0
申请日：2007-06-15
申请人： Pharma Mar S.A.
发明人： Martín López, Mª Jesús , Coello Molinero, Laura , Reyes Benítez, José Fernando , Rodríguez Vicente, Alberto , Garranzo GarcÍa-Ibarrola, María , Murcia Pérez, Carmen , Francesch Solloso, Andrés , Sánchez Sancho, Francisco , Cuevas Marchante, María del Carmen , Fernández Rodríguez, Rogelio
IPC分类号： C07D309/32
CPC分类号： C07D309/32
摘要： A process and intermediates for the preparation of a compound of general formula (I), or a pharmaceutically acceptable salt, tautomer, or stereoisomer thereof
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公开(公告)号：EP2295979A3
公开(公告)日：2011-10-05
申请号：EP10187154.9
申请日：2007-04-30
申请人： Expedeon Limited
IPC分类号： G01N33/68
CPC分类号： G01N33/6833 , G01N33/6839 , Y10T436/25125
摘要： The invention provides reagents, methods and kits for detection of proteins and quantitative determination of protein concentration. The reagents comprise a protein-complexing dye, such as a Coomassie dye and one or more dextrins, for the elimination of interference caused by detergents.
摘要翻译： 本发明提供了用于蛋白质检测和蛋白质浓度定量测定的试剂，方法和试剂盒。 试剂包含蛋白质复合染料，如考马斯染料和一种或多种糊精，用于消除由清洁剂引起的干扰。
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