-
11.发明公开A RUMEN BYPASS COMPOSITION CONTAINING A BIOACTIVE SUBSTANCE AND A METHOD FOR ITS PREPARATION 有权PANSE渗透成分含生物活性物质及过程及其
公开(公告)号：EP1381285A1
公开(公告)日：2004-01-21
申请号：EP02717030.7
申请日：2002-04-08
CPC分类号： A23K50/10 , A23K20/142 , A23K20/174 , A23K40/35
摘要： A rumen bypass composition containing a bioactive substance capable of releasing said bioactive substance into the post rumen portion of the digestive system of a ruminant without introducing into the rumen of the digestive system is disclosed. The composition is in the form of beadlets and comprises of a core consisting of a bioactive substance; a hydrophobic coating material, which completely encapsulates the core to avoid interaction within the rumen of a ruminant; an adjuvant hydrophobic in nature having a melting range 50-80°C added to the coating material to improve thermal resistance wherein said beadlets have a size of about 2 to 8 mm, the amount of said bioactive material being in the range of 30 to 60% of the weight of the beadlet, the amount of said coating material is in the range of from 40 to 80% by weight and the amount of said adjuvant being in the range of from 5 to 50% based on the weight of said coating material. The method preparation comprises of mixing an aqueous bioactive substance with a coating material, heating the mixture under constant stirring at a temperature in the range of 55 to 80°C to produce a molten mass, allowing drops of said molten mass to fall from a height through precooled air over a cold surface to obtain said composition in the form of beadlets.
-
公开(公告)号：EP1979313A1
公开(公告)日：2008-10-15
申请号：EP06711364.7
申请日：2006-01-31
发明人： GUPTA, Runjhun , RAM, Khushi , BHADWAL, Paramvir , THAPER, Rajesh, Kumar , DUBEY, Sushil, Kumar
IPC分类号： C07D207/00
CPC分类号： C07D207/34
摘要： Disclosed is a novel process for preparing pure amorphous form of Atorvastatin employing a suitable solvent system selected from water, water miscible solvents or water immiscible solvents or mixture thereof.
-
13.发明公开MOUTH DISSOLVING PHARMACEUTICAL COMPOSITION AND PROCESS FOR PREPARING THE SAME USING A HIGH AMOUNT OF SILICON DIOXINE 审中-公开在生产口中解决方案的药物组合物及其使用方法硅二恶英大量
公开(公告)号：EP1978939A2
公开(公告)日：2008-10-15
申请号：EP06796197.9
申请日：2006-08-30
发明人： KASHID, Namdev , MUKHERJI, Gour
IPC分类号： A61K9/20 , A61K31/167 , A61K31/445 , A61K31/54 , A61K31/551
CPC分类号： A61K9/0056 , A61K9/0007 , A61K9/2018 , A61K9/2077 , A61K9/2095 , A61K31/167 , A61K31/445 , A61K31/54 , A61K31/551 , A61K31/5513
摘要： Disclosed herein is a orally disintegrating and/or dissolving oral pharmaceutical composition, comprising one or more active pharmaceutical ingredients, one or more fillers having particle size of 100 microns or above, a high and desirable amount of silicon dioxide, one or more disintegrating agents, optionally effervescent couple, wherein said composition has good organoleptic properties like desired mouth feel and fast oral disintegration time.
-
公开(公告)号：EP1648869B1
公开(公告)日：2007-11-07
申请号：EP03817293.8
申请日：2003-12-31
发明人： KUMAR, Rajiv , JOSHI, Praphulla Narahar , CHAPEKAR, Gopal Moreshwar , NIPHADKAR, Prashant Suresh , AGARWAL, Ashutosh, Jubilant Organosys Limited , VERMA, Pradeep Kumar, Jubilant Organosys Limited , SINGH, Kumar Samir, Jubilant Organosys Limited
IPC分类号： C07D213/08 , C07D213/09
CPC分类号： C07D213/08 , C07D213/10
摘要： An process for the preparation of pyridine and/or picolines is disclosed. The process comprises contacting a mixture of carbonyl compound with ammonia in the presence of surface-passivated titanium-silicate catalyst in gas phas at a temperature ranging between 300-500°C, at gas space velocity in the range of 300 to 3000 h-1 and at a pressure ranging between 1 to 10 atmosphere, condensing and separating the products by conventional methods and if desired, further purifiying the product using well known conventional methods.
-
15.发明公开PROCESS FOR PRODUCING 1-BENZYL-4-[(5,6-DIMETHOXY-1-INDANON2-YL)METHYL] PIPERIDINE OR ITS SALT THEREOF VIA NOVEL INTERMEDIATE 有权用于生产1-苄基-4 - [（5,6-二甲氧基-1-二氢茚酮-2-基）甲基]哌啶或其盐上的新的中间
公开(公告)号：EP1841739A1
公开(公告)日：2007-10-10
申请号：EP04806779.7
申请日：2004-12-30
发明人： DUBEY, Shailendra Kumar, Jubilant Organosys Ltd , SHARMA, Amit Kumar, Jubilant Organosys Ltd , RANI, Beena S., Jubilant Organosys Ltd , PAUL, Soumendu, Jubilant Organosys Ltd , THAPER, Rajesh Kumar, Jubilant Organosys Limited , DUBEY, Sushil Kumar, Jubilant Organosys Ltd , KHANNA, Jag Mohan, Jubilant Organosys Ltd
IPC分类号： C07D211/70 , C07D211/82
CPC分类号： C07D213/89 , C07D211/22
摘要： Disclosed herein the process for producing 1-benzyl-4-[(5,6-dimethoxy-1-indanon-2yl)methyl]piperidine or its salt thereof employing novel intermediates.
-
公开(公告)号：EP1786765A1
公开(公告)日：2007-05-23
申请号：EP04770705.4
申请日：2004-09-08
发明人： SINGH, Govind, Jubilant Organosys Ltd , BHADWAL, Paramvir, Jubilant Organosys Ltd , JAISWAL, Sanjay, Jubilant Organosys Ltd , PANCHASARA, Dinesh R, Jubilant Organosys Ltd , THAPER, Rajesh Kumar, Jubilant Organosys Ltd , DUBEY, Sushil Kumar, Jubilant Organosys Ltd , KHANNA, Jag Mohan, Jubilant Organosys Ltd
IPC分类号： C07C309/30
CPC分类号： C07D309/30
摘要： The present invention relates to an improved and industrial friendly process for lactonization to produce compound of the Formula [I], from compound of the Formula [II] in presence of an inorganic compound as a suitable lactonizing agent, preferably alkali metal hydrogen sulfate, and crystallizing the obtained lactone product in a solvent; or treating compound of the Formula [II] in the presence of an inorganic compound preferably alkali metal hydrogen sulfate using phase transfer catalyst in heterogeneous phase followed by crystallizing the obtained lactone product in a solvent.
-
17.发明公开A PROCESS FOR THE PRODUCTION OF HETEROAROMATIC NITRILES, AN IMPROVED CATALYST THEREFOR AND A PROCESS FOR THE PRODUCTION OF SAID IMPROVED CATALYST 审中-公开用于生产芳香杂环NITRILES，改进催化剂THEREFOR和生产这种催化剂的方法
公开(公告)号：EP1425269A1
公开(公告)日：2004-06-09
申请号：EP02700562.8
申请日：2002-02-15
发明人： VERMA, Pradeep K.,c/o. Jubilant Organosys Limited , AGARWAL, Ashutosh,c/o. Jubilant Organosys Limited
IPC分类号： C07D213/84 , C07F9/90
CPC分类号： B01J37/0221 , B01J21/04 , B01J23/002 , B01J23/22 , B01J23/26 , B01J35/008 , B01J35/1009 , B01J37/0219 , B01J37/038 , B01J2523/00 , C07D213/84 , B01J2523/53 , B01J2523/55 , B01J2523/67
摘要： A process for preparation of heteroaromatic nitrile from the corresponding alkyl pyridine is disclosed. The process comprises contacting the alkyl pyridine with ammonia and an oxygen source in the presence of a catalyst comprising an active component comprising of oxide of vanadium and antimony and a promoter provided on a support.
-
18.发明公开Process for producing 4-dimethyl amino pyridine (4-DMAP) 有权Verfahren zur Herstellung von 4-二甲基氨基吡啶（4-DMAP）
公开(公告)号：EP1424328A1
公开(公告)日：2004-06-02
申请号：EP03004093.5
申请日：2003-02-25
IPC分类号： C07D213/74
CPC分类号： C07D213/74
摘要： An improved process for producing 4-dimethyl amino pyridine is provided. The process comprises quaternizing pyridine with a suitable quaternizing agent in the presence of organic solvent, isolating the resulting salt and aminating the salt, N- [4-pyridyl] pyridinium chloride hydrochloride, with N, N-dimethyl formamide. The resultant reaction mass is hydrolysed in the presence of a base, extracted with a suitable organic solvent and distilled under vacuum to produce 4-dimethyl amino pyridine.
摘要翻译： 提供了一种改进的制备4-二甲基氨基吡啶的方法。 该方法包括在有机溶剂存在下用合适的季铵化剂季铵化吡啶，分离得到的盐，并用N，N-二甲基甲酰胺胺化盐，N-哒嗪基氯化吡啶鎓盐酸盐。 所得反应物质在碱的存在下水解，用合适的有机溶剂萃取并真空蒸馏，得到4-二甲基氨基吡啶。
-
19.发明公开A process for producing 4-(4-halo-1-oxybutyl)-alpha,alpha-dimethylbenzene acetic acid or alkyl esters thereof 审中-公开一种制备的4-（4-卤代-1-氧代丁基）-α，α-dimethylbenzeneacetic酸，或其烷基酯的过程
公开(公告)号：EP2289867A3
公开(公告)日：2012-04-25
申请号：EP10008531.5
申请日：2010-08-16
IPC分类号： C07C45/67 , C07C51/16 , C07C67/08 , C07C67/293 , C07C69/738 , C07C69/007 , C07C49/82 , C07C59/86 , C07C67/11
CPC分类号： C07C67/293 , C07C45/676 , C07C51/16 , C07C67/08 , C07C67/11 , C07C69/738 , C07C2601/02 , C07C49/83 , C07C59/86 , C07C69/007 , C07C69/157
摘要： Disclosed herein is a process for large scale production of pure 4-(4-halo-1-oxybutyl)-α,α-dimethylbenzene acetic acid or alkyl esters thereof, wherein the process comprises of condensing (2-halo-1,1-dimethyl-ethyl)benzene with acetate salt followed by acylation with ω-halo compound, hydrolyzing and cyclizing the resultant regioisomers, subsequently oxidizing and purifying to obtain pure regioisomer, further halogenating and/or esterifying the para regioisomer to produce 4-(4-halo-1-oxybutyl)-α,α-dimethylbenzene acetic acid or their alkyl esters.
-
20.发明公开A process for producing 4-(4-halo-1-oxybutyl)-alpha,alpha-dimethylbenzene acetic acid or alkyl esters thereof 审中-公开Verfahren zur Herstellung von 4-（4-卤代-1-氧丁基）-α，α-二甲基苯甲醚无机化合物
公开(公告)号：EP2289867A2
公开(公告)日：2011-03-02
申请号：EP10008531.5
申请日：2010-08-16
IPC分类号： C07C45/67 , C07C51/16 , C07C67/08 , C07C67/293 , C07C69/738 , C07C69/007 , C07C49/82 , C07C59/86
CPC分类号： C07C67/293 , C07C45/676 , C07C51/16 , C07C67/08 , C07C67/11 , C07C69/738 , C07C2601/02 , C07C49/83 , C07C59/86 , C07C69/007 , C07C69/157
摘要： Disclosed herein is a process for large scale production of pure 4-(4-halo-1-oxybutyl)-α,α-dimethylbenzene acetic acid or alkyl esters thereof, wherein the process comprises of condensing (2-halo-1,1-dimethyl-ethyl)benzene with acetate salt followed by acylation with ω-halo compound, hydrolyzing and cyclizing the resultant regioisomers, subsequently oxidizing and purifying to obtain pure regioisomer, further halogenating and/or esterifying the para regioisomer to produce 4-(4-halo-1-oxybutyl)-α,α-dimethylbenzene acetic acid or their alkyl esters.
摘要翻译： 本文公开了一种大规模生产纯4-（4-卤代-1-氧丁基） - ，± - 二甲基苯乙酸或其烷基酯的方法，其中该方法包括冷凝（2-卤代-1- 二甲基 - 乙基）苯，然后用-卤代化合物酰化，水解和环化所得区域异构体，随后氧化和纯化以获得纯区域异构体，进一步卤化和/或酯化该对位异构体以产生4-（4-卤代 -1-氧丁基） - ±，± - 二甲基苯乙酸或其烷基酯。
-
-
-
-
-
-
-
-
-
搜索结果
33 条记录 (耗时 0.012 秒)
