公开(公告)号：EP0082880A4

公开(公告)日：1984-01-12

申请号：EP82902505

申请日：1982-07-08

申请人： KEY PHARMA

发明人： KEITH ALEC DELL ,  SNIPES WALLACE

IPC分类号： A61K31/16 ,  A61K9/00 ,  A61K9/70 ,  A61K31/047 ,  A61K31/135 ,  A61L15/03

CPC分类号： A61K9/7007 ,  A61K31/135 ,  C07K2319/02 ,  C07K2319/55 ,  C07K2319/74

摘要： A self-supporting polymeric diffusion matrix provides for the sustained release of propranolol in order to deliver the propranolol to a patient. The matrix comprises from about 1 to about 60 % of a polar plasticizer, from about 6 to about 30 % by weight polyvinylalcohol, from about 2 to about 30 % by weight polyvinylpyrrolidone, and a pharmaceutically effective amount of propranolol to provide a sustained release of propranolol over a prolonged period.

公开(公告)号：EP0050654A4

公开(公告)日：1983-06-17

申请号：EP81901257

申请日：1981-04-22

申请人： KEY PHARMA

发明人： SACKNER MARVIN A ,  WATSON HERMAN

IPC分类号： A61B5/08 ,  A61B5/091 ,  A61B5/097 ,  A61M11/00 ,  A61M11/06 ,  A61M15/00 ,  A61M16/00

CPC分类号： A61M15/00 ,  A61M15/0086 ,  A61M15/0088 ,  A61M15/009

摘要： Apparatus for administering pulmonary medication to control the concentration thereof or a fixed volume of air comprising a mouthpiece (19) having one end adapted to communicate with a human oral cavity and a second end communicating with an inflatable envelope (11). The inflatable envelope further includes stays (13) for maintaining the interior surfaces of the envelope apart. A nebulizer (17) is disposed within the mouthpiece having one end terminating in an opening (17a) in the side wall of the mouthpiece for receiving an aerosolized medicant, and the remaining end (18) of the nebulizer is directed towards the inflatable envelope whereby aerosolized medicant is directed into the envelope before being expelled by a negative pressure applied to said mouthpiece through a bidirectional channel (17c) in the nebulizer.

公开(公告)号：EP0020532A4

公开(公告)日：1981-01-12

申请号：EP79901407

申请日：1980-04-22

申请人： KEY PHARMA

发明人： FROST PHILLIP ,  KEITH ALEC D

IPC分类号： A61K8/30 ,  A61K8/33 ,  A61K8/36 ,  A61K8/365 ,  A61K8/37 ,  A61K8/39 ,  A61K8/41 ,  A61K8/55 ,  A61K8/63 ,  A61K8/73 ,  A61K8/96 ,  A61K47/18 ,  A61K47/24 ,  A61Q19/00 ,  A61K31/685 ,  A61K31/13

CPC分类号： A61K8/63 ,  A61K8/41 ,  A61K8/553 ,  A61K9/0014 ,  A61K47/18 ,  A61K47/24 ,  A61Q19/00

摘要： A skin preparation capable of prolonged moisturizing action provides a layer of protection at the surface of the skin and the immediately joining layers just below the skin. The skin preparation is an aqueous mixture which contains from 1 to about 4% by weight of lecithin-containing phosphatide mixture and at least equimolar amount of triethanolamine, the range of triethanolamine being from about 0.15% to about 3.0% by weight of the total composition.

摘要翻译： 能够延长保湿作用的皮肤制剂在皮肤表面提供一层保护，并在皮肤下方立即接合层。 该皮肤制剂是一种含水混合物，其含有1至约4重量％的含卵磷脂的磷脂混合物和至少等摩尔量的三乙醇胺，三乙醇胺的范围为全部组合物的约0.15重量％至约3.0重量％ 。