公开(公告)号：EP2566881A1

公开(公告)日：2013-03-13

申请号：EP11723687.7

申请日：2011-05-05

申请人： Centre National de la Recherche Scientifique ,  Université Montpellier I

发明人： GERGELY, Csilla ,  ESTEPHAN, Elias ,  SAAB, Marie-Belle ,  LARROQUE, Christian ,  CUISINIER, Frédéric

IPC分类号： C07K7/08 ,  C07K17/14 ,  A61K47/02 ,  A61K47/48 ,  G01N33/552

CPC分类号： C07K17/14 ,  C07K7/08 ,  G01N33/54353 ,  G01N33/551

摘要： The present invention relates to the use of a peptide consisting of 5 to 30 amino acid residues comprising an amino acid sequence selected from LLADTTHHRPWT (SEQ ID NO: 1), SPGLSLVSHMQT (SEQ ID NO: 2), and the sequences presenting at least 80% identity with SEQ ID NO: 1 or SEQ ID NO: 2, for the funcfionalization of silicon substrate. The present invention also relates to the specific peptides as such, and to silicon substrates functionalized by the adsorption on their surface of such specific peptides. Finally, the present invention is also directed to a process for the preparation of such functionalized silicon substrates, and to articles comprising a silicon substrate according to the invention.

公开(公告)号：EP2694715A2

公开(公告)日：2014-02-12

申请号：EP12720250.5

申请日：2012-04-05

申请人： Universite Montpellier 2, Sciences ET Techniques (Etablissement Public) ,  Université Montpellier I ,  Ecole Nationale Superieure De Chimie Montpellier (ENSC) ,  Centre National de la Recherche Scientifique

发明人： HABAS, Jean-Pierre ,  STEMMELEN, Mylène ,  LAPINTE, Vincent ,  CAILLOL, Sylvain ,  BOUTEVIN, Bernard ,  RICBOURG, Maxime

IPC分类号： D04H1/64

CPC分类号： D21H17/53 ,  D04H1/64

摘要： The invention relates to a sheet of vegetable wool fibre impregnated with a reactive mix made up of a partially or completely epoxidised vegetable oil and a hardener. The invention also relates to a panel including a sheet according to the invention. The invention further relates to a method for manufacturing a sheet or a panel according to the invention, comprising the following steps: mixing an epoxidised vegetable oil and a hardener at a temperature higher than each one of the melting temperatures thereof and lower than each one of the breakdown temperatures thereof; depositing the obtained mix on an assembly of vegetable wool fibres at a temperature higher than each one of the melting temperatures thereof and lower than each one of the breakdown temperatures thereof.

公开(公告)号：EP1527101A2

公开(公告)日：2005-05-04

申请号：EP03756532.2

申请日：2003-08-07

申请人： Bio-Rad Pasteur ,  CENTRE NATIONAL DELA RECHERCHE SCIENTIFIQUE (CNRS) ,  Université Montpellier I

发明人： PAU, Bernard ,  GIULIANI, Isabelle ,  RIEUNIER, François

IPC分类号： C07K16/26 ,  C12N5/12 ,  G01N33/53 ,  C07K7/06 ,  C07K7/08 ,  C07K16/06 ,  G01N33/74 ,  C12N5/20

CPC分类号： C07K16/26 ,  C07K14/58 ,  C07K2317/34

摘要： The invention relates to in vitro diagnosis of heart failure. More specifically, the invention relates to specific antibodies of a peptide domain which is situated on either side of hinge region R76S77 of proBNP(1-108). In particular, the invention relates to a method of obtaining the aforementioned antibodies and to the use thereof in detecting blood proBNP(1-108) with the exception of BNP(1-76) and BNP(77-108). The invention also relates to a method of detecting blood proBNP(1-108), reagents and a kit for same.

公开(公告)号：EP2569333A1

公开(公告)日：2013-03-20

申请号：EP11718450.7

申请日：2011-04-01

申请人： LFB Biotechnologies ,  Université Montpellier I ,  Centre National de Lutte contre le Cancer ,  INSERM (Institut National de la Santé et de la Recherche Médicale)

发明人： BEHRENS, Christian ,  NAVARRO-TEULON, Isabelle

IPC分类号： C07K16/00 ,  C07K16/28 ,  C07K16/30

CPC分类号： C07K16/2863 ,  A61K31/282 ,  A61K31/337 ,  A61K31/7088 ,  A61K33/24 ,  A61K39/3955 ,  A61K39/39558 ,  A61K45/06 ,  A61K2039/505 ,  C07K16/2869 ,  C07K16/46 ,  C07K2317/24 ,  C07K2317/34 ,  C07K2317/565 ,  C07K2317/567 ,  C07K2317/622 ,  C07K2317/64 ,  C07K2317/73 ,  C07K2317/732 ,  C07K2317/92 ,  G01N33/57449 ,  G01N2333/72

摘要： The invention relates to novel mutated humanized 12G4 antibodies and to the fragments thereof against the anti-Müllerian hormone receptor type II.

摘要翻译： 新颖突变的人源化抗体12G4，以及它们的片段，针对抗苗勒激素II型受体。

公开(公告)号：EP1527101B1

公开(公告)日：2010-10-27

申请号：EP03756532.2

申请日：2003-08-07

申请人： Bio-Rad Pasteur ,  CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) ,  Université Montpellier I

发明人： PAU, Bernard ,  GIULIANI, Isabelle ,  RIEUNIER, François

IPC分类号： C07K16/26 ,  C12N5/12 ,  G01N33/53 ,  C07K7/06 ,  C07K7/08 ,  C07K16/06 ,  G01N33/74 ,  C12N5/20

CPC分类号： C07K16/26 ,  C07K14/58 ,  C07K2317/34

公开(公告)号：EP2170290A1

公开(公告)日：2010-04-07

申请号：EP08832081.7

申请日：2008-07-18

申请人： Centre National de la Recherche Scientifique ,  Université Montpellier I

发明人： VERT, Michel ,  LECLERCQ, Laurent ,  BOUSTTA, Mahfoud

IPC分类号： A61K9/20 ,  A61K9/70 ,  A61K47/48

CPC分类号： A61K47/48207 ,  A61K9/204 ,  A61K9/2045 ,  A61K9/7007 ,  A61K47/593 ,  A61K47/645

摘要： The invention relates to a system for controlled release of an active principle, comprising at least (a) a degradable polymer matrix which produces acid compounds and (b) at least one acid-sensitive complex of an active principle having at least one electrostatic charge and a complexing polyelectrolyte partner of opposite charge which complexes with the active principle. The invention further relates to a method for preparation of such a system. The release of the active principle (7P) is prolonged over 18 days (ternary system PMLA/7P/PLAGA) in comparison to binary systems (7P/PLAGA) and (PMLA/7P).

公开(公告)号：EP1694707B1

公开(公告)日：2009-12-09

申请号：EP04806335.8

申请日：2004-12-14

申请人： INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) ,  Centre Regional de Lutte Contre le Cancer "Val ,  Université Montpellier I

发明人： GAUTHIER, Philippe ,  PELEGRIN, André ,  COELHO, Mickaël ,  TEULON, Isabelle

IPC分类号： C07K16/42 ,  A61K39/395 ,  C12N5/08 ,  A61K35/12 ,  A61P35/00

CPC分类号： C07K16/4258 ,  A61K2039/505 ,  A61K2039/5154 ,  A61K2039/5158 ,  C07K2317/21 ,  C07K2317/622

摘要： This invention relates to human anti-idiotypic antibody fragments, especially scFv, characterized by the ability to mimic Her-2/neu tumor associated antigen. These antibody fragments are promising candidates for active immunotherapy for cancer patients positive for Her-2/neu.