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1.发明授权NOUVEAUX ANTICORPS HUMANISES 12G4 MUTES ET LEURS FRAGMENTS DIRIGES CONTRE LE RECEPTEUR HUMAIN DE L'HORMONE ANTI-MULLERIENNE DE TYPE II 有权新型12G4突变型人源化抗体及其片段指向人类II型抗甲状腺激素受体
公开(公告)号：EP2569333B1
公开(公告)日：2017-12-13
申请号：EP11718450.7
申请日：2011-04-01
申请人： Laboratoire Français du Fractionnement et des Biotechnologies , Université Montpellier I , Centre Régional de Lutte contre le Cancer , INSERM (Institut National de la Santé et de la Recherche Médicale)
IPC分类号： C07K16/00 , C07K16/28 , C07K16/30 , A61K31/282 , A61K39/395 , A61K31/337 , A61K31/7088 , A61K33/24 , C07K16/46 , A61K39/00
CPC分类号： C07K16/2863 , A61K31/282 , A61K31/337 , A61K31/7088 , A61K33/24 , A61K39/3955 , A61K39/39558 , A61K45/06 , A61K2039/505 , C07K16/2869 , C07K16/46 , C07K2317/24 , C07K2317/34 , C07K2317/565 , C07K2317/567 , C07K2317/622 , C07K2317/64 , C07K2317/73 , C07K2317/732 , C07K2317/92 , G01N33/57449 , G01N2333/72
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2.发明公开HÉTÉROCYCLES PHOSPHORÉS ANALOGUES DE SUCRES À ACTIVITÉ ANTIMÉTASTATIQUE 审中-公开ZUCKERANALOGE PHOSPHORHALTIGE HETEROCYCLEN MIT ANTIMETASTATISCHER WIRKUNG
公开(公告)号：EP2958569A1
公开(公告)日：2015-12-30
申请号：EP14711831.9
申请日：2014-02-25
申请人： Centre National de la Recherche Scientifique (CNRS) , Ecole Nationale Superieure De Chimie Montpellier (ENSC) , Université Montpellier I , Université Montpellier 2, Sciences et Techniques , Universite Paris 13 Nord , Université Paris-Sud 11
发明人： BAKALARA, Norbert , DELAFORGE, Marcel , LECOUVEY, Marc , HUGNOT, Jean-Philippe , LEGRAND, Philippe , PIRAT, Jean-Luc , VIRIEUX, David , VOLLE, Jean-Noël
IPC分类号： A61K31/665 , A61P35/00
CPC分类号： C07F9/657172 , A61K9/0019 , A61K9/08 , A61K31/665 , A61K31/67 , A61K31/675 , A61K45/06 , A61K47/14 , C07D493/04 , C07F9/6552 , C07F9/65522 , A61K2300/00
摘要： The invention relates to the use of compounds of formula (1) as defined in the description, for reducing or preventing the onset of metastases in a patient suffering from cancer. The invention also relates to pharmaceutical compositions for using in human or veterinary medicine, comprising at least one compound of formula (1).
摘要翻译： 使用描述中定义的式（1）化合物，用于减少或预防患有癌症的患者中转移的发生。 还描述了用于人或兽医学包括至少一种式（1）化合物的药物组合物。
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3.发明公开
公开(公告)号：EP2864756A1
公开(公告)日：2015-04-29
申请号：EP13731791.3
申请日：2013-06-26
申请人： Centre National de la Recherche Scientifique (CNRS) , Université Montpellier I , Université Montpellier 2, Sciences et Techniques
CPC分类号： G01N15/0205 , G01N15/02 , G01N15/0211 , G01N35/085
摘要： This method comprises steps consisting in: injecting (100) a sample into a capillary tube; conveying (110) the sample along the capillary tube, under experimental conditions able to generate a Taylor dispersion effect; generating (120) a signal characterising the Taylor dispersion; processing (130) said signal to obtain the experimental Taylor signal
Ŝ (
t ); and analysing (200) said experimental Taylor signal
Ŝ(t) . The analyzing step consists in obtaining an amplitude distribution
P(G (c) ) allowing said experimental Taylor signal
Ŝ (t) to be decomposed into a sum of Gaussian functions by implementing a constraint-solving algorithm consisting in minimising a cost function
H a comprising at least one constraint term associated with a constraint that the amplitude distribution
P(G (c) ) must respect, this minimisation being carried out over a range of values of interest of a parameter
G (c) characterising the Gaussian amplitude function
P(G (c) ) .-
4.发明授权SYSTEME A LIBERATION CONTROLEE D'UN PRINCIPE ACTIF ET PROCEDE DE PREPARATION 有权SYSTEM FOR其生产的积极和方法控释
公开(公告)号：EP2170290B1
公开(公告)日：2015-01-21
申请号：EP08832081.7
申请日：2008-07-18
CPC分类号： A61K47/48207 , A61K9/204 , A61K9/2045 , A61K9/7007 , A61K47/593 , A61K47/645
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公开(公告)号：EP2751287A1
公开(公告)日：2014-07-09
申请号：EP12780105.8
申请日：2012-10-01
申请人： Université Montpellier 2, Sciences et Techniques , Institut Curie , INSERM (Institut National de la Santé et de la Recherche Scientifique) , Centre Hospitalier Universitaire de Montpellier , Centre National de la Recherche Scientifique , Université Montpellier I
发明人： JOUBERT, Dominique , BAUCHET, Luc , HUGNOT, Jean-Philippe , BIECHE, Ivan , LIDEREAU, Rosette , REME, Thierry , DUFFAU, Hugues , RIGAU, Valérie
IPC分类号： C12Q1/68
CPC分类号： C12Q1/6886 , C12Q2600/112 , C12Q2600/118 , C12Q2600/158 , G06F19/20 , G16H50/30
摘要： Disclosed is a method of determining the survival prognosis of a patient afflicted by a glioma. The method includes assessing the level of expression of one or more specific gene in cells of the glioma.
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6.发明授权
公开(公告)号：EP2864756B1
公开(公告)日：2016-04-13
申请号：EP13731791.3
申请日：2013-06-26
申请人： Centre National de la Recherche Scientifique (CNRS) , Université Montpellier I , Université Montpellier 2, Sciences et Techniques
CPC分类号： G01N15/0205 , G01N15/02 , G01N15/0211 , G01N35/085
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7.发明公开NOUVELLES COMPOSITIONS PHARMACEUTIQUES COMPRENANT UN ANTICORPS LIANT LE RECEPTEUR HUMAIN DE L'HORMONE ANTI-MULLERIENNE DE TYPE II 审中-公开与人类抗MUELLER激素II型受体结合抗体新的药物组合
公开(公告)号：EP2793942A1
公开(公告)日：2014-10-29
申请号：EP12819106.1
申请日：2012-12-21
申请人： Laboratoire Français du Fractionnement et des Biotechnologies , Centre National de Lutte contre le Cancer , INSERM - Institut National de la Santé et de la Recherche Médicale , Université Montpellier I
IPC分类号： A61K39/395 , C07K16/28 , A61K31/282 , A61K31/337 , A61P35/00 , A61K33/00
摘要： The invention relates to novel pharmaceutical compositions comprising, as active substance, an antibody which binds the human anti-Mullerian hormone receptor type II (AMHR-II) and an anticancer agent, and also to the therapeutic uses of these compositions.
摘要翻译： 本发明涉及新的药物组合物，包括，作为活性成分，在抗体结合的人抗苗勒激素II型受体（AMHR-II）和抗癌剂，以及合成的组合物的治疗应用。
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公开(公告)号：EP2715363A1
公开(公告)日：2014-04-09
申请号：EP12727138.5
申请日：2012-06-01
申请人： Université Montpellier 2 Sciences et Techniques , Université Montpellier I , Centre Hospitalier Universitaire de Montpellier - France , Centre National de la Recherche Scientifique
发明人： TUAILLON, Edouard , RUBBO, Pierre-Alain , CANAAN, Stephane , KREMER, Laurent , NAGOT, Nicolas , VAN DE PERRE, Philippe , VENDRELL, Jean-Pierre
IPC分类号： G01N33/569 , C07K14/35 , C12N9/20
CPC分类号： G01N33/5695 , C12N9/20
摘要： The present invention relates to a method for the
in vitro diagnosis of active tuberculosis, comprising a step of contacting lymphocytes of a patient suspected to have active tuberculosis with at least one protein of mycobacteria, said protein being an enzyme having a lipolytic activity (eg a monoacylglycerol hydrolase such as Rv0183, a phospholipase such as Rv3452, Rv3802c, PlcA, PlcB, PlcC or PlcD, the lipase Rv1984c, or a triacylglycerol hydrolase, such as LipY), and a step of detecting the presence of specific activated lymphocytes.-
公开(公告)号：EP1694707A1
公开(公告)日：2006-08-30
申请号：EP04806335.8
申请日：2004-12-14
申请人： INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) , Centre Regional de Lutte Contre le Cancer "Val , Université Montpellier I
IPC分类号： C07K16/42 , A61K39/395 , C12N5/08 , A61K35/12 , A61P35/00
CPC分类号： C07K16/4258 , A61K2039/505 , A61K2039/5154 , A61K2039/5158 , C07K2317/21 , C07K2317/622
摘要： This invention relates to human anti-idiotypic antibody fragments, especially scFv, characterized by the ability to mimic Her-2/neu tumor associated antigen. These antibody fragments are promising candidates for active immunotherapy for cancer patients positive for Her-2/neu.
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10.发明公开Compounds for the treatment and/or prevention of parasitic diseases and method of production thereof 审中-公开化合物用于治疗和/或预防寄生虫病的，并且它们的制备方法
公开(公告)号：EP2826769A1
公开(公告)日：2015-01-21
申请号：EP13177129.7
申请日：2013-07-18
发明人： Sereno, Denis , Labesse, Gilles , Guichou, Jean-François Alexandre , Loeuillet, Corinne , Garcia, Déborah Isabelle
IPC分类号： C07C259/10 , C07C311/19 , C07C311/21 , C07D277/30 , A61K31/16 , A61K31/18 , A61K31/426 , A61P33/02
CPC分类号： C07C259/06 , C07C259/10 , C07C311/19 , C07C311/21 , C07D277/30
摘要： The present invention relates to new compounds for treating, preventing or inhibiting a parasitic disease, preferably toxoplasmosis in a subject, the method for preparing thereof.
摘要翻译： 本发明涉及新的化合物用于治疗，预防或抑制受试者中的，用于其制备方法优选寄生虫病，弓形体病。
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