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公开(公告)号：EP1622880B1
公开(公告)日：2007-02-28
申请号：EP04728119.1
申请日：2004-04-17
申请人： Bayer HealthCare AG
发明人： WUNBERG, Tobias , BAUMEISTER, Judith , BETZ, Ulrich , JESKE, Mario , LAMPE, Thomas , NIKOLIC, Susanne , REEFSCHLÄGER, Jürgen , SCHOHE-LOOP, Rudolf , SÜSSMEIER, Frank , ZIMMERMANN, Holger , GROSSER, Rolf , HENNINGER, Kerstin , HEWLETT, Guy , KELDENICH, Jörg , LANG, Dieter , NELL, Peter
IPC分类号： C07D239/84 , A61K31/517 , A61P31/22
CPC分类号： C07D239/84
摘要： The invention relates to substituted dihydrochinazolines of formula (I), methods for the production thereof, and the use thereof for producing medicaments used for treating and/or preventing diseases, particularly as antiviral agents, especially against cytomegaloviruses.
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公开(公告)号：EP1622880A1
公开(公告)日：2006-02-08
申请号：EP04728119.1
申请日：2004-04-17
申请人： Bayer HealthCare AG
发明人： WUNBERG, Tobias , BAUMEISTER, Judith , BETZ, Ulrich , JESKE, Mario , LAMPE, Thomas , NIKOLIC, Susanne , REEFSCHLÄGER, Jürgen , SCHOHE-LOOP, Rudolf , SÜSSMEIER, Frank , ZIMMERMANN, Holger , GROSSER, Rolf , HENNINGER, Kerstin , HEWLETT, Guy , KELDENICH, Jörg , LANG, Dieter , NELL, Peter
IPC分类号： C07D239/84 , A61K31/517 , A61P31/22
CPC分类号： C07D239/84
摘要： The invention relates to substituted dihydrochinazolines of formula (I), methods for the production thereof, and the use thereof for producing medicaments used for treating and/or preventing diseases, particularly as antiviral agents, especially against cytomegaloviruses.
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13.发明公开2-(3-PHENYL-2-PIPERAZINYL-3,4-DIHYDROCHINAZOLIN-4-YL) ESSIGSÄUREN ALS ANTIVIRALE MITTEL, SPEZIELL GEGEN CYTOMEGALIEVIREN 有权2-（3-苯基-2-哌嗪基-3,4-二氢喹唑啉-4-基）乙酸可用作抗病毒剂，特别是在巨细胞病毒
公开(公告)号：EP1603888A1
公开(公告)日：2005-12-14
申请号：EP04706148.6
申请日：2004-01-29
申请人： Bayer HealthCare AG
发明人： WUNBERG, Tobias , BAUMEISTER, Judith , BETZ, Ulrich , JESKE, Mario , KLEYMANN, Gerald , LAMPE, Thomas , NIKOLIC, Susanne , REEFSCHLÄGER, Jürgen , SCHOHE-LOOP, Rudolf , SÜßMEIER, Frank , ZIMMERMANN, Holger , GROSSER, Rolf , HENNINGER, Kerstin , HEWLETT, Guy , KELDENICH, Jörg , KRÄMER, Thomas , NELL, Peter , LIN, Tse-I
IPC分类号： C07D239/84 , A61K31/517 , A61P31/22
CPC分类号： C07D239/84
摘要： The invention relates to dihydroquinazolines and methods for the production thereof, the use thereof in the treatment and/or prophylaxis of diseases, in addition to the use thereof in the production of medicaments in the treatment and/or prophylaxis of diseases, especially for use as anti-viral agents, especially against cytomegalo viruses.
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公开(公告)号：EP1339403B1
公开(公告)日：2004-12-08
申请号：EP01989448.4
申请日：2001-11-09
申请人： Bayer HealthCare AG
发明人： KROLL, Werner , ROMBOUT, Ferdinand , WEBER, Horst , RODRIGUEZ, Maria-Luisa , SENNHENN, Bernd , SCHOHE-LOOP, Rudolf
IPC分类号： A61K31/35 , A61K31/425 , A61K39/395 , A61K31/44 , G01N33/94
CPC分类号： C07D417/12 , G01N33/94
摘要： The invention relates to a kit comprising a pharmaceutical composition that contains repinotan or a physiologically acceptable salt of repinotan, and to a means for determining the concentration of repinotan or its metabolites in body fluids. The invention further relates to novel pharmaceutical compositions that contain repinotan or a physiologically acceptable salt of repinotan, and to a method for producing the same.
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15.发明公开BENZISOTHIAZOLYL-SUBSTITUIERTE AMINOMETHYLCHROMANE ZUR BEHANDLUNG VON ERKRANKUNGEN DES ZENTRALEN NERVENSYSTEMS 审中-公开苯并异噻唑取代氨基甲基二氢吡喃中枢神经系统疾病的治疗
公开(公告)号：EP1434777A1
公开(公告)日：2004-07-07
申请号：EP02767489.4
申请日：2002-09-18
申请人： Bayer HealthCare AG
发明人： SCHERLING, Dietrich , KARL, Wolfgang , SEIDEL, Dietrich , WEINZ, Corinna , SCHOHE-LOOP, Rudolf , MAULER, Frank
IPC分类号： C07D417/12 , A61K31/425 , A61P25/00
CPC分类号： C07D417/12
摘要： The invention relates to chromanes of formula (I), to a method for the production thereof and to their use in medicaments, particularly as agents for fighting diseases of the central nervous system.
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