公开(公告)号：EP1583967A2

公开(公告)日：2005-10-12

申请号：EP03795968.1

申请日：2003-12-24

申请人： Bayer HealthCare AG

发明人： BETZ, Ulrich ,  HEWLETT, Guy ,  KLEYMANN, Gerald ,  LAMPE, Thomas ,  LIN, Tse-I ,  NIKOLIC, Susanne ,  REEFSCHLÄGER, Jürgen ,  WUNBERG, Tobias ,  ZIMMERMANN, Holger ,  ZUMPE, Franz ,  BENDER, Wolfgang ,  HENNINGER, Kerstin ,  JENSEN, Axel ,  KELDENICH, Jörg ,  SCHOHE-LOOP, Rudolf

IPC分类号： G01N33/569 ,  A61P31/22

CPC分类号： C07C311/08 ,  C07C275/40 ,  C07D237/04 ,  G01N33/56994 ,  G01N2500/00

摘要： The invention relates to a method for inhibiting the replication of herpes viruses, to methods for identifying compounds that inhibit the replication of herpes viruses with this method, to compounds with activity directed against herpes viruses, to methods for producing these compounds, and to the use thereof for producing medicaments used in the treatment of herpes infections.

公开(公告)号：EP1472229A1

公开(公告)日：2004-11-03

申请号：EP03734671.5

申请日：2003-01-16

申请人： Bayer HealthCare AG

发明人： WUNBERG, Tobias ,  BETZ, Ulrich ,  KLEYMANN, Gerald ,  NIKOLIC, Susanne ,  REEFSCHLÄGER, Jürgen ,  SCHOHE-LOOP, Rudolf ,  ZIMMERMANN, Holger ,  ZUMPE, Franz ,  BENDER, Wolfgang ,  HENNINGER, Kerstin ,  HEWLETT, Guy ,  JENSEN, Axel ,  KELDENICH, Jörg

IPC分类号： C07D231/20 ,  C07D231/54 ,  C07D249/12 ,  A61K31/4152 ,  A61K31/4196 ,  A61K31/12

CPC分类号： C07D249/12 ,  C07D231/20 ,  C07D231/54

摘要： The invention relates to 5-ring heterocycles, methods for the production thereof, and the use thereof for the production of medicines used for treating or preventing diseases, particularly medicines used as antiviral agents, particularly against cytomegaloviruses.

公开(公告)号：EP1401436A1

公开(公告)日：2004-03-31

申请号：EP02760172.3

申请日：2002-06-10

申请人： Bayer HealthCare AG

发明人： SCHOHE-LOOP, Rudolf ,  BETZ, Ulrich ,  FISCHER, Rüdiger ,  HENDRIX, Martin ,  KLEYMANN, Gerald ,  BAUMEISTER, Judith ,  BENDER, Wolfgang ,  ECKENBERG, Peter ,  HANDKE-ERGüDEN, Gabrielle ,  HENNINGER, Kerstin ,  JENSEN, Axel ,  KELDENICH, Jörg ,  SCHNEIDER, Udo ,  WEBER, Olaf

IPC分类号： A61K31/427 ,  C07D401/12 ,  C07D277/36

CPC分类号： C07D417/12 ,  C07D277/54

摘要： The invention relates to the novel compounds of formula (I), to a method for producing the same and to their use as drugs, especially as antiviral drugs.

公开(公告)号：EP1244641B1

公开(公告)日：2005-04-13

申请号：EP00991169.4

申请日：2000-12-12

申请人： Bayer HealthCare AG

发明人： FISCHER, Rüdiger ,  KLEYMANN, Gerald ,  BETZ, Ulrich ,  BAUMEISTER, Judith ,  BENDER, Wolfgang ,  ECKENBERG, Peter ,  HANDKE, Gabriele ,  HENDRIX, Martin ,  HENNINGER, Kerstin ,  JENSEN, Axel ,  KELDENICH, Jörg ,  SCHNEIDER, Udo ,  WEBER, Olaf

IPC分类号： C07D277/54 ,  C07D417/12 ,  C07F9/6539 ,  C07F7/18 ,  A61K31/426 ,  A61P31/22

CPC分类号： C07D231/12 ,  C07D233/56 ,  C07D249/08 ,  C07D277/54 ,  C07D417/12 ,  C07F7/1856 ,  C07F9/6539

公开(公告)号：EP1507757A1

公开(公告)日：2005-02-23

申请号：EP03725145.1

申请日：2003-05-05

申请人： Bayer HealthCare AG

发明人： WUNBERG, Tobias ,  BAUMEISTER, Judith ,  BETZ, Ulrich ,  JENSEN, Axel ,  NIKOLIC, Susanne ,  REEFSCHLÄGER, Jürgen ,  ZIMMERMANN, Holger ,  ZUMPE, Franz ,  GROSSER, Rolf ,  KLEYMANN, Gerald ,  BENDER, Wolfgang ,  HENNINGER, Kerstin ,  HEWLETT, Guy ,  KELDENICH, Jörg

IPC分类号： C07D207/26 ,  A61K31/4015 ,  A61P31/12

CPC分类号： C07D207/26

摘要： The invention relates to lactams, to methods for producing the same and to the use thereof for producing medicaments for the treatment and/or prophylaxis of diseases, in particular for use as anti-viral agents specifically against cytomegaloviruses.

公开(公告)号：EP1404657A1

公开(公告)日：2004-04-07

申请号：EP02740725.3

申请日：2002-06-17

申请人： Bayer HealthCare AG

发明人： WUNBERG, Tobias ,  BETZ, Ulrich ,  HALLENBERGER, Sabine ,  KLEYMANN, Gerald ,  LAMPE, Thomas ,  NIKOLIC, Susanne ,  REEFSCHLÄGER, Jürgen ,  ZUMPE, Franz ,  BAUSER, Marcus ,  BENDER, Wolfgang ,  GROSSER, Rolf ,  HENNINGER, Kerstein ,  HEWLETT, Guy ,  JENSEN, Axel ,  KELDENICH, Jörg ,  ZIMMERMANN, Holger

IPC分类号： C07D237/04 ,  C07D237/32 ,  C07D417/12 ,  A61K31/50 ,  A61P31/12

CPC分类号： C07D417/12 ,  C07D237/04 ,  C07D237/32

摘要： The invention relates to novel compounds, to a method for the production of said compounds and to the use thereof as medicaments, more particularly as antiviral agents, especially against cytomegalovirus.

公开(公告)号：EP1603888A1

公开(公告)日：2005-12-14

申请号：EP04706148.6

申请日：2004-01-29

申请人： Bayer HealthCare AG

发明人： WUNBERG, Tobias ,  BAUMEISTER, Judith ,  BETZ, Ulrich ,  JESKE, Mario ,  KLEYMANN, Gerald ,  LAMPE, Thomas ,  NIKOLIC, Susanne ,  REEFSCHLÄGER, Jürgen ,  SCHOHE-LOOP, Rudolf ,  SÜßMEIER, Frank ,  ZIMMERMANN, Holger ,  GROSSER, Rolf ,  HENNINGER, Kerstin ,  HEWLETT, Guy ,  KELDENICH, Jörg ,  KRÄMER, Thomas ,  NELL, Peter ,  LIN, Tse-I

IPC分类号： C07D239/84 ,  A61K31/517 ,  A61P31/22

CPC分类号： C07D239/84

摘要： The invention relates to dihydroquinazolines and methods for the production thereof, the use thereof in the treatment and/or prophylaxis of diseases, in addition to the use thereof in the production of medicaments in the treatment and/or prophylaxis of diseases, especially for use as anti-viral agents, especially against cytomegalo viruses.

公开(公告)号：EP1161423B1

公开(公告)日：2004-11-10

申请号：EP00907614.2

申请日：2000-02-24

申请人： Bayer HealthCare AG

发明人： FISCHER, Rüdiger ,  KLEYMANN, Gerald ,  BAUMEISTER, Judith ,  BENDER, Wolfgang ,  BETZ, Ulrich ,  ECKENBERG, Peter ,  HANDKE, Gabriele ,  HENDRIX, Martin ,  SCHNEIDER, Udo ,  WEBER, Olaf ,  HENNINGER, Kerstin ,  JENSEN, Axel ,  KELDENICH, Jörg

IPC分类号： C07D277/54 ,  C07D417/12 ,  C07D487/04 ,  A61K31/426 ,  A61K31/427 ,  A61P31/12

CPC分类号： C07D231/12 ,  C07D233/56 ,  C07D249/08 ,  C07D277/54 ,  C07D417/12 ,  C07D487/04

公开(公告)号：EP1401435B1

公开(公告)日：2006-03-15

申请号：EP02743172.5

申请日：2002-06-10

申请人： Bayer HealthCare AG

发明人： BETZ, Ulrich ,  LAICH, Tobias ,  BENDER, Wolfgang ,  FISCHER, Rüdiger ,  HENDRIX, Martin ,  KLEYMANN, Gerald

IPC分类号： A61K31/426 ,  A61K31/427 ,  A61K9/06 ,  A61P31/12

CPC分类号： A61K31/427 ,  A61K9/0014 ,  A61K9/0048 ,  A61K31/426 ,  A61K47/06 ,  A61K47/10 ,  A61K47/32 ,  A61K47/34

摘要： The invention relates to the topical application of substituted thiazolyl amides in the treatment of herpes infections in humans, to preparations suitable for the topical application and to the production thereof.

公开(公告)号：EP1401435A1

公开(公告)日：2004-03-31

申请号：EP02743172.5

申请日：2002-06-10

申请人： Bayer HealthCare AG

发明人： BETZ, Ulrich ,  LAICH, Tobias ,  BENDER, Wolfgang ,  FISCHER, Rüdiger ,  HENDRIX, Martin ,  KLEYMANN, Gerald

IPC分类号： A61K31/426 ,  A61K31/427 ,  A61K9/06 ,  A61P31/12

CPC分类号： A61K31/427 ,  A61K9/0014 ,  A61K9/0048 ,  A61K31/426 ,  A61K47/06 ,  A61K47/10 ,  A61K47/32 ,  A61K47/34

摘要： The invention relates to the topical application of substituted thiazolyl amides in the treatment of herpes infections in humans, to preparations suitable for the topical application and to the production thereof.