公开(公告)号：EP2464742A2

公开(公告)日：2012-06-20

申请号：EP10761051.1

申请日：2010-08-12

申请人： Biomérieux

发明人： ZAMBARDI, Gilles ,  ROCHE, Jean-Marc

IPC分类号： C12Q1/14

CPC分类号： C12Q1/14

摘要： The present invention relates to a reaction medium for detecting and/or identifying methicillin-resistant
Staphylococcus aureus (MRSA) bacteria, said medium containing a chromogenic substrate, a first antibiotic that belongs to the cephalosporin family, and a second antibiotic that belongs to the aminoside family.

摘要翻译： 本发明涉及用于检测和/或鉴定耐甲氧西林金黄色葡萄球菌（MRSA）细菌的反应介质，所述培养基含有显色底物，属于头孢菌素家族的第一抗生素和属于该氨基苷的第二抗生素 家庭。

公开(公告)号：EP2459732A1

公开(公告)日：2012-06-06

申请号：EP10752006.6

申请日：2010-07-13

申请人： Biomérieux

发明人： ZAMBARDI, Gilles

IPC分类号： C12Q1/04

CPC分类号： C12Q1/04 ,  C12Q1/045 ,  C12Q1/34 ,  G01N2333/924

摘要： The invention relates to a reaction medium for gram-negative bacteria having a beta-lactam antibiotic resistance mechanism. Said reaction medium comprises a marker for the beta-lactam antibiotic resistance mechanism, said marker being cefepime, and an inhibitor of a resistance mechanism other than said beta-lactam antibiotic resistance mechanism.

公开(公告)号：EP4058591A1

公开(公告)日：2022-09-21

申请号：EP20861979.1

申请日：2020-11-13

申请人： bioMérieux

发明人： CHARRIER, Jean-Philippe ,  PERROT, Nadine ,  ZAMBARDI, Gilles

IPC分类号： C12Q1/18 ,  G01N33/68

公开(公告)号：EP3298158B1

公开(公告)日：2019-07-10

申请号：EP16730879.0

申请日：2016-05-19

申请人： Biomérieux ,  Institut National de la Santé et de la Recherche Médicale (I.N.S.E.R.M.) ,  Université d'Aix Marseille ,  Service de Santé des Armées (SSA)

发明人： FRANCESCHI, Christine ,  PINET, Elizabeth ,  PAGES, Jean-Marie ,  ZAMBARDI, Gilles

IPC分类号： C12Q1/18 ,  C12Q1/04 ,  A61K31/397

公开(公告)号：EP3298158A1

公开(公告)日：2018-03-28

申请号：EP16730879.0

申请日：2016-05-19

申请人： Biomérieux ,  Institut National de la Santé et de la Recherche Médicale (I.N.S.E.R.M.) ,  Université d'Aix Marseille ,  Service de Santé des Armées (SSA)

发明人： FRANCESCHI, Christine ,  PINET, Elizabeth ,  PAGES, Jean-Marie ,  ZAMBARDI, Gilles

IPC分类号： C12Q1/18 ,  C12N1/20 ,  C12Q1/04

CPC分类号： C12Q1/18 ,  A61K31/397 ,  C12N1/20 ,  C12Q1/045

摘要： The invention relates to a method for discriminating bacteria that are resistant to carbapenems according to whether or not they develop resistance by membrane imperviousness, said method comprising the following steps: providing a bacteria strain that is resistant to at least one carbapenem; assessing the sensitivity of said bacterial strain with regard to at least one indicator carbapenem, in the absence of polymyxin B nonapeptide (PMBN) as well as in the presence of PMBN in a non-inhibiting concentration; and establishing a prognosis of resistance by membrane imperviousness in the case that the presence of PMBN makes it possible significantly to increase the sensitivity of said bacterial strain with regard to at least one indicator carbapenem used.

公开(公告)号：EP2877591A1

公开(公告)日：2015-06-03

申请号：EP13756613.9

申请日：2013-07-29

申请人： Biomérieux

发明人： DEVIGNE, Laurence ,  GHIRARDI, Sandrine ,  ZAMBARDI, Gilles

IPC分类号： C12Q1/04 ,  C12Q1/10

CPC分类号： G01N33/56911 ,  C12Q1/04 ,  C12Q1/045 ,  C12Q1/10 ,  G01N2333/986 ,  G01N2458/00

摘要： The present invention relates to a method of detecting and/or specific identification of bacteria producing OXA-048-type carbapenemase in a biological sample, comprising the steps consisting of: a) placing the biological sample likely to contain said bacteria in contact with a reaction medium comprising at least one chromogenic substrate to detect an enzymatic activity, and temocillin at a concentration equal to or greater than 150 mg/L, preferably between 200 and 500 mg/L, b) incubating said sample in the medium to allow the bacteria to grow, and c) detecting the strains corresponding to the OXA-48 carbapenemase producing bacteria. The invention also relates to a culture medium as implemented in step a).

公开(公告)号：EP2344662A1

公开(公告)日：2011-07-20

申请号：EP09755979.3

申请日：2009-10-07

申请人： Biomérieux

发明人： ORENGA, Sylvain ,  ROBICHON, Denis ,  ZAMBARDI, Gilles

IPC分类号： C12Q1/04 ,  C12Q1/14

CPC分类号： C12Q1/045 ,  C12Q1/14

摘要： The present invention relates to a reaction medium for detecting and/or identifying methicillin-resistant
Staphylococcus aureus (MRSA) bacteria, comprising a predetermined combination of two antibiotics, a first antibiotic which belongs to the cephalosporin family and a second antibiotic, said first antibiotic and second antibiotic each being at a sub-inhibitory concentration.