专利检索 ap:("Bristol-Myers Squibb Company") AND inv:"ZHENG, Bin" 第 2 页

11.

发明公开
PROCESS FOR THE PREPARATION OF 6-(CYCLOPROPANEAMIDO)-4-((2-METHOXY-3-(1-METHYL-1H-1,2,4-TRIAZOL-3-YL)PHENYL)AMINO)-N-(METHYL-D3)PYRIDAZINE-3-CARBOXAMIDE 审中-实审

公开(公告)号：EP4296258A3

公开(公告)日：2024-03-20

申请号：EP23209227.0

申请日：2018-03-29

申请人： Bristol-Myers Squibb Company

发明人： CHEN, Ke , DEERBERG, Joerg , LIN, Dong , DUMMELDINGER, Michael , INANKUR, Bahar , KOLOTUCHIN, Sergei V , LI, Jun , ROGERS, Amanda J , ROSSO, Victor W , SIMMONS, Eric M , SOUMEILLANT, Maxime C. D , TREITLER, Daniels S , WANG, Jianji , ZHENG, Bin , SMITH, Michael J , STROTMAN, Neil A , TYMONKO, Steven , BENKOVICS, Tamas

IPC分类号： C07D403/12 , A61K31/501 , A61P29/00

摘要： The invention relates to an improved process for synthesizing 6-(cyclopropaneamido)-4-((2-methoxy-3-(1-methyl-1H-1,2,4-triazol-3-yl)phenyl)amino)-N-(methyl-d3)pyridazine-3-carboxamide of the formula:

Compound I is currently in clinical trials for the treatment of auto-immune and auto-inflammatory diseases such as psoriasis.

12.

发明公开
PROCESS FOR THE PREPARATION OF 6-(CYCLOPROPANEAMIDO)-4-((2-METHOXY-3-(1-METHYL-1H-1,2,4-TRIAZOL-3-YL)PHENYL)AMINO)-N-(METHYL-D3)PYRIDAZINE-3-CARBOXAMIDE 审中-公开

公开(公告)号：EP3882237A3

公开(公告)日：2021-11-03

申请号：EP21155321.9

申请日：2018-03-29

申请人： Bristol-Myers Squibb Company

发明人： CHEN, Ke , DEERBERG, Joerg , LIN, Dong , DUMMELDINGER, Michael , INANKUR, Bahar , KOLOTUCHIN, Sergei V. , LI, Jun , ROGERS, Amanda J. , ROSSO, Victor W. , SIMMONS, Eric M. , SOUMEILLANT, Maxime C. D. , TREITLER, Daniel S. , WANG, Jianji , ZHENG, Bin , SMITH, Michael J. , STROTMAN, Neil A. , TYMONKO, Steven , BENKOVICS, Tamas

IPC分类号： C07D249/08 , C07C209/02 , C07C211/04

摘要： The invention relates to an improved process for synthesizing 6-(cyciopropaneamido)-4-((2-methoxy-3-(1-methyl-1H-1,2,4-triazol-3-yl)phenyl)amino)-N-(methyl-d3)pyridazine-3-carboxamide of the formula:

Compound I is currently in clinical trials for the treatment of auto-immune and auto-inflammatory diseases such as psoriasis.

13.

发明公开
NOVEL PHOSPHOROUS (V)-BASED REAGENTS, PROCESSES FOR THE PREPARATION THEREOF, AND THEIR USE IN MAKING STEREO-DEFINED ORGANOPHOSHOROUS (V) COMPOUNDS 审中-公开

公开(公告)号：EP3774824A1

公开(公告)日：2021-02-17

申请号：EP19720286.4

申请日：2019-04-12

申请人： Bristol-Myers Squibb Company , The Scripps Research Institute

发明人： SCHMIDT, Michael Anthony , ZHENG, Bin , KNOUSE, Kyle , DEGRUYTER, Justine , EASTGATE, Martin D. , BARAN, Phil , EWING, William R. , OLSON, Richard E. , MCDONALD, Ivar M.

IPC分类号： C07F9/6574 , C07H19/00 , C07H19/11 , C07H21/04

14.

发明公开
PROCESS FOR THE PREPARATION OF N-((1R,2S,5R)-5-(TERT 审中-公开

公开(公告)号：EP3655395A2

公开(公告)日：2020-05-27

申请号：EP18785785.9

申请日：2018-07-19

申请人： Bristol-Myers Squibb Company

发明人： AYTAR, Burcu Selin , BOROVIKA, Alina , CHAN, Collin , DEERBERG, Joerg , DOMAGALSKI, Nathan R. , EASTGATE, Martin D. , FAN, Yu , FENSTER, Michael David Bengt , FOREST, Robert V. , GONZALEZ-BOBES, Francisco , GREEN, Rebecca A. , HICKEY, Matthew R. , KOPP, Nathaniel David , LA CRUZ, Thomas E. , LAUSER, Kathleen , LEE, Hong Geun , LEAHY, David K. , LUO, Helen Y. , RAZLER, Thomas M. , SAVAGE, Scott A. , SFOUGGATAKIS, Chris , SOUMEILLANT, Maxime C.D. , ZARETSKY, Serge , ZHENG, Bin , ZHU, Ye

IPC分类号： C07D235/06 , C07C233/41 , C07D487/04 , C07D207/273