公开(公告)号：EP1626681B1

公开(公告)日：2009-07-01

申请号：EP04752669.4

申请日：2004-05-19

申请人： Cook Incorporated

发明人： OSBORNE, Thomas, A. ,  CASE, Brian, C. ,  FLAGLE, Jacob, A. ,  HOFFA, Andrew, K. ,  GARRISON, Michael, L.

IPC分类号： A61F2/24

CPC分类号： A61F2/2418 ,  A61F2/2475 ,  A61F2220/0008 ,  A61F2220/0016 ,  A61F2220/0075 ,  A61F2230/0026 ,  A61F2230/0095

摘要： Medical devices for implantation in a body vessel are provided. A medical device according to the invention comprises a support structure and one or more graft members comprising a valve portion and a constraining portion. The support structure has a first, unexpanded configuration and a second, expanded configuration. The constraining portion is adapted to substantially prevent the support structure from achieving the second, expanded configuration. The valve portion is adapted to permit fluid flow through a body vessel in a first direction and substantially prevent fluid flow through the vessel in a second, opposite direction.

公开(公告)号：EP1827557A1

公开(公告)日：2007-09-05

申请号：EP05854341.4

申请日：2005-12-15

申请人： Cook Incorporated

发明人： MELSHEIMER, Jeffry, S. ,  OSBORNE, Thomas, A.

IPC分类号： A61M29/02 ,  A61M25/10

CPC分类号： A61M25/104 ,  A61F2/958 ,  A61F2250/0039 ,  A61M25/1002 ,  A61M25/1027 ,  A61M2025/0039

摘要： A delivery system, including a balloon catheter having a balloon with distal and proximal ends and a guide catheter for delivering the balloon catheter to a treatment site, is disclosed. The balloon tapers from at least one of the distal and proximal ends of the balloon to an active region on the surface of the balloon. The active region has a diameter D, which is greater than a diameter of the balloon at one or more of the distal and proximal ends of the balloon. Preferably, one or more of the lengths L1, which is the distance from the proximal end of the balloon to the active region, and L2, which is the distance from the distal end of the balloon to the active region, are between three to thirty times the diameter D1.

公开(公告)号：EP1737389A1

公开(公告)日：2007-01-03

申请号：EP05734203.2

申请日：2005-04-12

申请人： Cook Incorporated

发明人： OSBORNE, Thomas, A. ,  EELLS, Scott, E.

IPC分类号： A61F2/06

CPC分类号： A61F2/07 ,  A61F2/848 ,  A61F2/89 ,  A61F2002/061 ,  A61F2002/065 ,  A61F2002/067 ,  A61F2002/072 ,  A61F2002/075 ,  A61F2002/826 ,  A61F2002/8483 ,  A61F2002/8486 ,  A61F2220/0008 ,  A61F2220/0016 ,  A61F2220/0075 ,  A61F2230/0013 ,  A61F2230/005 ,  A61F2230/0054 ,  A61F2230/0067 ,  A61F2250/0069

摘要： A repair device (10) for affixing a migrating stent graft (30) to the interior surface of a vessel wall (31). The repair device includes tubular graft (11) with a bare or uncovered stent (16) affixed to the proximal end (12). The bare stent includes a plurality of distally pointed barbs (17) for securing the repair device to a vessel wall. A second stent (15) is positioned in the passage (14) of the tubular graft to expand the graft against the interior surface of the migrating stent graft (30). Proximally pointing barbs (20) are affixed to the struts of the second stent and extend through the graft material for securing the repair device to the migrating stent graft. Biological glue (22) and other sealing material (23) can be applied to the tubular graft and/or stents for sealing the repair device against the vessel wall and/or the interior of the migrating stent graft.

摘要翻译： 一种用于将迁移性支架移植物（30）固定到血管壁（31）的内表面的修复装置（10）。 修复装置包括具有固定到近端（12）上的裸露或未覆盖的支架（16）的管状移植物（11）。 裸露的支架包括用于将修复装置固定到血管壁的多个向远侧尖的倒钩（17）。 第二支架（15）定位在管状移植物的通道（14）中，以使移植物抵靠移植的支架移植物（30）的内​​表面膨胀。 将近端指向倒钩（20）固定到第二支架的支柱并且延伸穿过移植材料，以将修复装置固定到迁移性支架移植物。 可以将生物胶（22）和其它密封材料（23）应用于管状移植物和/或支架，用于将修复装置密封抵靠血管壁和/或迁移性支架移植物的内部。

公开(公告)号：EP1301235B1

公开(公告)日：2004-10-06

申请号：EP01952720.9

申请日：2001-07-13

申请人： Cook Incorporated

发明人： PARKER, Fred, T. ,  OSBORNE, Thomas, A.

IPC分类号： A61M25/00

CPC分类号： A61L29/126 ,  A61L29/02 ,  A61L29/04 ,  A61M25/0053 ,  A61M25/0054 ,  A61M2025/0079

摘要： A medical device (10) including a tube (11) having a highly uniform and repeatable inner and outer diameter, the tube (11) possessing good trackability, pushability and torquability, and the tube (11) being highly resistant to collapse, necking or kinking during use. The tube (11) first includes a metal coil (14) in a stressed, radially expanded condition, the metal coil (14) preferably being formed as a flat wire. The tube (11) also includes a metal braid (16) extending over at least part of the coil (14) and further includes a polymeric bonding layer (18) positioned over and contacting at least the coil (14). The tube (11) optionally includes an inner liner (20) beneath and in contact with at least part of the coil (14). The polymeric layer (18) maintains the coil (14) in its stressed, radially expanded condition.

公开(公告)号：EP1301235A2

公开(公告)日：2003-04-16

申请号：EP01952720.9

申请日：2001-07-13

申请人： Cook Incorporated

发明人： PARKER, Fred, T. ,  OSBORNE, Thomas, A.

IPC分类号： A61M25/00

CPC分类号： A61L29/126 ,  A61L29/02 ,  A61L29/04 ,  A61M25/0053 ,  A61M25/0054 ,  A61M2025/0079

摘要： A medical device (10) including a tube (11) having a highly uniform and repeatable inner and outer diameter, the tube (11) possessing good trackability, pushability and torquability, and the tube (11) being highly resistant to collapse, necking or kinking during use. The tube (11) first includes a metal coil (14) in a stressed, radially expanded condition, the metal coil (14) preferably being formed as a flat wire. The tube (11) also includes a metal braid (16) extending over at least part of the coil (14) and further includes a polymeric bonding layer (18) positioned over and contacting at least the coil (14). The tube (11) optionally includes an inner liner (20) beneath and in contact with at least part of the coil (14). The polymeric layer (18) maintains the coil (14) in its stressed, radially expanded condition.

公开(公告)号：EP1087727A1

公开(公告)日：2001-04-04

申请号：EP99927150.5

申请日：1999-06-02

申请人： Cook Incorporated

发明人： PAVCNIK, Dusan ,  KELLER, Frederick, S. ,  ROSCH, Josef ,  OSBORNE, Thomas, A.

IPC分类号： A61F2/06

CPC分类号： A61F2/86 ,  A61F2/07 ,  A61F2/2475 ,  A61F2/848 ,  A61F2/89 ,  A61F2002/075 ,  A61F2002/8483 ,  A61F2002/8486 ,  A61F2220/0008 ,  A61F2220/0016 ,  A61F2220/005 ,  A61F2220/0058 ,  A61F2220/0075 ,  A61F2230/0008 ,  A61F2230/005 ,  A61F2230/0095

摘要： A multiple-sided medical device comprises a closed frame of a single piece of wire or other resilient material and having a series of bends and interconnecting sides. The device has both a flat configuration and a second, folded configuration that comprises a self-expanding stent. The stent is pushed from a delivery catheter into the lumen of a duct or vessel. One or more barbs are attached to the frame of the device for anchoring or to connect additional frames. A covering of fabric or other flexible material such as DACRON, PTFE, or collagen, is sutured or attached to the frame to form an occlusion device, a stent graft, or an artificial valve such as for correcting incompetent veins in the lower legs and feet. A partial, triangular-shaped covering over the lumen of the device allows the valve to open with normal blood flow and close to retrograde flow.

公开(公告)号：EP0952795A1

公开(公告)日：1999-11-03

申请号：EP97947517.0

申请日：1997-11-14

申请人： Cook Incorporated

发明人： FONTAINE, Arthur, B. ,  DOSPASSOS, Susan ,  BATES, Brian, L. ,  BOATMAN, Scott, E. ,  HOFFA, Michael, C. ,  OSBORNE, Thomas, A.

IPC分类号： A61F2 ,  A61M25

CPC分类号： A61F2/97 ,  A61F2/95 ,  A61F2/958 ,  A61F2002/9511 ,  A61F2002/9583 ,  A61M25/0668 ,  A61M25/10

摘要： A stent deployment device (10) includes a catheter (12), a stent (14) positioned on the catheter (12), and a sleeve (16) carried on the catheter (12). The sleeve (16) has a portion (18) extending fully over and containing the stent (14). The stent deployment device (10) also includes a mechanism (20) for splitting at least the portion (18) of the sleeve (16) extending over the stent (14) and, preferably, for splitting the entire sleeve (16). Splitting of the sleeve portion (18) permits expansion of the stent (14). The mechanism (20) can include an inflatable, nondistending balloon (22) carried on the catheter (12), the stent (14) and the sleeve portion (18) being positioned over the balloon (22). The stent (14) can be self-expanding or can be expanded by the balloon (22) itself. It is preferred that at least the portion (18) of the sleeve (16) extending over the stent (14) includes a longitudinally extending structure (46) for ensuring that the sleeve portion (18) will in fact split upon operation of the mechanism (20).

公开(公告)号：EP1971273B1

公开(公告)日：2010-12-01

申请号：EP07716401.0

申请日：2007-01-09

申请人： Cook Incorporated

发明人： OSBORNE, Thomas, A.

IPC分类号： A61B17/00

CPC分类号： A61B17/0057 ,  A61B17/0644 ,  A61B17/0684 ,  A61B2017/00349 ,  A61B2017/00353 ,  A61B2017/00575

摘要： A device for closure of a patent foramen ovale. The device includes at least one elongated tissue anchor at the distal end of the device. A distal end portion of the tissue anchor is selectively deployable between a closed position in which the distal end portion of the tissue anchor is capable of penetrating the septum and the flap, and a radially extensible position in which the distal end portion of the tissue anchor is capable of engaging the septum or flap so that the septum and flap may be urged into registry. A deployment member is associated with the tissue anchor for selectively deploying the distal end portion of the tissue anchor between the closed position and the radially extensible position. A closure element is disposed at the distal end of the device. The closure element is engageable with the septum and the flap when the septum and flap are in registry, for maintaining such registry. An actuator is associated with the closure element for selectively engaging the closure element with the septum and flap.

公开(公告)号：EP1871310A2

公开(公告)日：2008-01-02

申请号：EP06750814.3

申请日：2006-04-20

申请人： Cook Incorporated

发明人： PAL, Dharmendra ,  AGNEW, Charles, W. ,  FLAGLE, Jacob, A. ,  LENTZ, D., Christian ,  MELSHEIMER, Jeffry, S. ,  OSBORNE, Thomas, A. ,  PARKER, Fred, T.

IPC分类号： A61F2/84

CPC分类号： A61M25/0662 ,  A61F2/95 ,  A61F2002/9517 ,  A61M25/0045 ,  A61M25/005 ,  A61M25/0053

摘要： Delivery systems for self-expanding devices are provided having a system proximal portion with a handle, an elongate middle section delivery device with an outer sheath and inner compression member, and a system distal portion including an outer guide channel member with first and second end portions defining a guide channel that slidably receives an inner guide channel member having a guide channel, the guide channels being substantially aligned. A mounting region for self-expanding devices is disposed radially between the inner and outer guide channel members. The outer guide channel member has a stepped profile from a first outer diameter to a second smaller outer diameter located near a transition region having a breech position opening for passage of a wire guide, catheter, or other medical instrument. The outer member is axially slideable relative to the inner member to deploy a self-expanding device. Methods of using and manufacturing are also provided.

公开(公告)号：EP1819390A1

公开(公告)日：2007-08-22

申请号：EP05853186.4

申请日：2005-12-06

申请人： Cook Incorporated

发明人： HAWKINS, Kem, M. ,  OSBORNE, Thomas, A.

IPC分类号： A61M25/00

CPC分类号： A61M25/0017 ,  A61B17/3415 ,  A61B2017/00778 ,  A61M25/005

摘要： An apparatus (10) for providing percutaneous access to a vessel of a patient over a wire guide. The apparatus comprising an outer sleeve (12) with open ends, and inner sleeve (20) with distal open ends received in the outer sleeve, and a stiffening cannula (30) within the lumen of inner sleeve. The inner sleeve and the stiffening cannula being engaged such that relative axial movement between them is inhibited and the inner sleeve distal portion shields the stiffening cannula during percutaneous introduction into the vessel.

摘要翻译： 一种装置（10），用于通过导丝器提供经皮进入患者血管。 该装置包括具有开口端的外套管（12）和具有容纳在外套管中的远端开口端的内套管（20）以及位于内套管内腔内的加强套管（30）。 内套筒和加强套管被接合，使得它们之间的相对轴向运动被阻止，并且内套筒远端部分在经皮引入血管期间遮蔽加强套管。