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    COMBINATIONS INCLUDING CRY3AA AND CRY6AA PROTEINS TO PREVENT DEVELOPMENT OF RESISTANCE IN CORN ROOTWORMS (DIABROTICA SPP.)
    15.
    发明公开
    COMBINATIONS INCLUDING CRY3AA AND CRY6AA PROTEINS TO PREVENT DEVELOPMENT OF RESISTANCE IN CORN ROOTWORMS (DIABROTICA SPP.) 有权
    WITH AND CRY3AA-蛋白CRY6AA组合防止产生抗性在玉米根钻DEVELOPMENT（叶甲属）。

    公开(公告)号：EP2560478A1

    公开(公告)日：2013-02-27

    申请号：EP11772790.9

    申请日：2011-04-22

    申请人： Dow AgroSciences, LLC

    发明人： NARVA, Kenneth, E. ,  MEADE, Thomas ,  FENCIL, Kristin, J. ,  LI, Huarong ,  HEY, Timothy, D. ,  WOOSLEY, Aaron, T. ,  OLSON,Monica, Britt

    IPC分类号： A01H5/00 ,  C12N5/04 ,  A01N37/18

    CPC分类号： C12N15/8286 ,  A01G22/00 ,  A01H5/10 ,  A01N37/18 ,  A01N43/50 ,  B32B1/02 ,  B65D85/00 ,  C07K14/325 ,  Y02A40/162 ,  Y10T428/13

    摘要： The subject invention relates in part to Cry34Ab/35Ab in combination with Cry6Aa. The subject invention relates in part to the surprising discovery that combinations of Cry34Ab/Cry35Ab and Cry6Aa are useful for preventing development of resistance (to either insecticidal protein system alone) by a corn rootworm (Diabrotica spp.) population. Included within the subject invention are plants producing these insecticidal Cry proteins, which are useful to mitigate concern that a corn rootworm population could develop that would be resistant to either of these insecticidal protein systems alone. Plants (and acreage planted with such plants) that produce these two insecticidal protein systems are included within the scope of the subject invention. The subject invention also relates in part to combinations of Cry34Ab/35Ab and Cry3Aa proteins "triple stacked" with a Cry6Aa protein. Transgenic plants, including corn, comprising a cry6Aa gene, cry34Ab/35Ab genes, and a cry3Aa gene are included within the scope of the subject invention. Thus, such embodiments target rootworms with three modes of action.

    摘要翻译： 本主题发明涉及在与Cry6Aa组合部分Cry34Ab / 35AB。 本主题发明部分地涉及令人惊讶的发现所做Cry34Ab / Cry35Ab和Cry6Aa的组合是用于由玉米根虫防治耐药性的发展（单独的任一杀昆虫蛋白系统）有用（叶甲属）种群。 包括在本发明中是植物生产合成杀虫Cry蛋白，这些都是减轻的关注做了一个玉米根虫群可以发展做了单独会是要么耐合成杀虫蛋白系统是有用的。 植物（和种植面积与检查植物）确实产生合成2个杀虫蛋白系统都包括在本发明的范围之内。 本主题发明部分因此涉及具有Cry6Aa蛋白Cry34Ab / 35AB和的Cry3Aa蛋白的结合“三层堆叠”。 转基因植物，包括玉米，包括cry6Aa基因，cry34Ab / 35AB基因，以及基因的Cry3Aa被包括在本发明的范围之内。 因此，调查了实施例中的目标用行动的三种模式根虫。

    COMBINATIONS INCLUDING CRY34AB/35AB AND CRY6AAPROTEINS TO PREVENT DEVELOPMENT OF RESISTANCE IN CORN ROOTWORMS(DIABROTICA SPP.)
    16.
    发明公开
    COMBINATIONS INCLUDING CRY34AB/35AB AND CRY6AAPROTEINS TO PREVENT DEVELOPMENT OF RESISTANCE IN CORN ROOTWORMS(DIABROTICA SPP.) 有权
    包括CRY34AB / 35AB和CRY6AAPROTEINS在内的组合，可预防玉米根尖病的发展（DIABROTICA SPP。）

    公开(公告)号：EP2560477A1

    公开(公告)日：2013-02-27

    申请号：EP11772789.1

    申请日：2011-04-22

    申请人： Dow AgroSciences, LLC

    发明人： NARVA, Kenneth, E. ,  MEADE, Thomas ,  FENCIL, Kristin, J. ,  LI, Huarong ,  HEY, Timothy, D. ,  WOOSLEY, Aaron, T. ,  OLSON, Monica, Britt

    IPC分类号： A01H5/00 ,  C12N5/02

    CPC分类号： C12N15/8286 ,  A01G22/00 ,  A01H5/10 ,  A01N37/18 ,  A01N43/50 ,  B32B1/02 ,  B65D85/00 ,  C07K14/325 ,  Y02A40/162 ,  Y10T428/13

    摘要： The subject invention relates in part to Cry34Ab/35Ab in combination with Cry6Aa. The subject invention relates in part to the surprising discovery that combinations of Cry34Ab/Cry35Ab and Cry6Aa are useful for preventing development of resistance (to either insecticidal protein system alone) by a corn rootworm (Diabrotica spp.) population. Included within the subject invention are plants producing these insecticidal Cry proteins, which are useful to mitigate concern that a corn rootworm population could develop that would be resistant to either of these insecticidal protein systems alone. Plants (and acreage planted with such plants) that produce these two insecticidal protein systems are included within the scope of the subject invention. The subject invention also relates in part to combinations of Cry34Ab/35Ab and Cry3Aa proteins "triple stacked" with a Cry6Aa protein. Transgenic plants, including corn, comprising a cry6Aa gene, cry34Ab/35Ab genes, and a cry3Aa gene are included within the scope of the subject invention. Thus, such embodiments target rootworms with three modes of action.

    摘要翻译： 本发明部分涉及与Cry6Aa组合的Cry34Ab / 35Ab。 本发明部分涉及令人惊讶的发现，即Cry34Ab / Cry35Ab和Cry6Aa的组合可用于预防玉米根虫（Diabrotica spp。）种群对抗（单独针对杀虫蛋白系统）的抗性发展。 包括在本发明中的是产生这些杀虫Cry蛋白的植物，其可用于减轻玉米根虫群体可能发展的对单独对这些杀虫蛋白系统中的任一个有抗性的担忧。 产生这两种杀虫蛋白质系统的植物（和种植这些植物的种植面积）包括在本发明的范围内。 本发明还部分涉及Cry3Ab / 35Ab和Cry3Aa蛋白与Cry6Aa蛋白“三重堆叠”的组合。 包含cry6Aa基因，cry34Ab / 35Ab基因和cry3Aa基因的转基因植物，包括玉米，包括在本发明的范围内。 因此，这些实施方案以三种作用模式针对根虫。

    USE OF CRY1AB IN COMBINATION WITH CRY1BE FOR MANAGEMENT OF RESISTANT INSECTS
    17.
    发明公开
    USE OF CRY1AB IN COMBINATION WITH CRY1BE FOR MANAGEMENT OF RESISTANT INSECTS 有权
    Cry1Ab蛋白联合使用CRY1BE抗昆虫COMBAT

    公开(公告)号：EP2513318A1

    公开(公告)日：2012-10-24

    申请号：EP10842620.6

    申请日：2010-12-16

    申请人： Dow AgroSciences, LLC

    发明人： MEADE, Thomas ,  NARVA, Kenneth ,  STORER, Nicholas, P. ,  SHEETS, Joel, J. ,  WOOSLEY, Aaron, T. ,  BURTON, Stephanie, L.

    IPC分类号： C12N15/82

    CPC分类号： C12N15/8286 ,  A01N63/02 ,  A01N65/00 ,  Y02A40/162 ,  A01N2300/00

    摘要： The subject invention relates in part to stacking Cry1Be toxins along with Cry1Fa toxins to prevent insects from developing resistance towards either toxin by itself. As discussed in more detail herein, the subject pair of proteins is a particularly advantageous combination, as no other pair of proteins is known to provide high levels of control and non-cross-resistant activity against both Spodoptera frugiperda (FAW) and Ostrinia nubilalis (ECB) insects. This dual, non-cross-resistant activity is also advantageous because it can reduce the number of proteins/genes needed to target these insects with multiple, non-cross-resistant proteins. This can reduce or eliminate the need for refuge acreage. Accordingly, the subject invention also relates generally to using four genes to provide three proteins for non-cross-resistant control of a first insect, and three proteins for non-cross-resistant control of a second insect. In preferred embodiments, the targeted insects are FAW and ECB.

    INSECT RESISTANCE MANAGEMENT WITH COMBINATIONS OF CRY1BE AND CRY1F PROTEINS
    18.
    发明公开
    INSECT RESISTANCE MANAGEMENT WITH COMBINATIONS OF CRY1BE AND CRY1F PROTEINS 有权
    了利用结合CRY1BE-和蛋白质的Cry1F杀虫管理

    公开(公告)号：EP2512218A1

    公开(公告)日：2012-10-24

    申请号：EP10838256.5

    申请日：2010-12-16

    申请人： Dow AgroSciences, LLC

    发明人： MEADE, Thomas ,  NARVA, Kenneth ,  STORER, Nicholas, P. ,  SHEETS, Joel, J. ,  WOOSLEY, Aaron, T. ,  BURTON, Stephenie, L.

    IPC分类号： A01H5/00 ,  A01H1/00 ,  A01P7/00

    CPC分类号： C12N15/8286 ,  A01N63/02 ,  A01N65/00 ,  Y02A40/162 ,  A01N2300/00

    摘要： The subject invention relates in part to stacking Cry1Be toxins along with Cry1Fa toxins to prevent insects from developing resistance towards either toxin by itself. As discussed in more detail herein, the subject pair of proteins is a particularly advantageous combination, as no other pair of proteins is known to provide high levels of control and non-cross-resistant activity against both Spodoptera frugiperda (FAW) and Ostrinia nubilalis (ECB) insects. This dual, non-cross-resistant activity is also advantageous because it can reduce the number of proteins/genes needed to target these insects with multiple, non-cross-resistant proteins. This can reduce or eliminate the need for refuge acreage. Accordingly, the subject invention also relates generally to using four genes to provide three proteins for non-cross-resistant control of a first insect, and three proteins for non-cross-resistant control of a second insect. In preferred embodiments, the targeted insects are FAW and ECB.