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公开(公告)号:EP3466971A1
公开(公告)日:2019-04-10
申请号:EP18190268.5
申请日:2007-10-31
申请人: Genentech, Inc.
发明人: WU, Herren , SINGH, Sanjaya , FUNG, Sek Chung , AN, Ling-Ling , LOWMAN, Henry B. , KELLEY, Robert F.
摘要: The invention relates to anti-Factor D antibodies and Factor D-binding fragments thereof, their nucleic acid sequences, the host cells and vectors that harbor these antibodies and Factor D-binding fragments, the method of making anti-Factor D antibodies and Factor D-binding fragments thereof, and the method of detecting Factor D. The invention also relates to compositions comprising the anti-Factor D antibodies or the Factor D-binding fragments thereof, their use in preparation of medicaments and treating disorders associated with excessive or uncontrolled complement activation.
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公开(公告)号:EP3192812A1
公开(公告)日:2017-07-19
申请号:EP17156352.1
申请日:2014-12-17
申请人: Genentech, Inc.
发明人: DENNIS, Mark S. , CHEN, Xiaocheng , EBENS, Allen J., Jr. , JUNTTILA, Teemu T. , KELLEY, Robert F. , MATHIEU, Mary A. , SUN, Liping L.
摘要: The disclosure provides anti-cluster of differentiation 3 (CD3) antibodies and methods of using the same.
摘要翻译: 本公开提供了抗分化3(CD3)抗体和使用其的方法。
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公开(公告)号:EP3137503A1
公开(公告)日:2017-03-08
申请号:EP15721516.1
申请日:2015-04-30
发明人: KELLEY, Robert F. , VAN LOOKEREN-CAMPAGNE, Menno , SCHEER, Justin M. , HASS, Philip E. , TESAR, Devin
CPC分类号: C07K16/40 , A61K9/0048 , A61K2039/505 , C07K2317/55 , C07K2317/76 , C07K2317/92 , C07K2317/94
摘要: The invention relates to anti-Factor D antibody variants, their production and their use in the preparation of compositions and medicaments for treatment of diseases and disorders associated with excessive or uncontrolled complement activation.
摘要翻译: 本发明涉及抗因子D抗体变体,其生产及其在制备用于治疗与过量或不受控补体活化相关的疾病和病症的组合物和药物中的用途。
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公开(公告)号:EP1973948B1
公开(公告)日:2015-02-11
申请号:EP06850958.7
申请日:2006-12-14
申请人: Genentech, Inc.
IPC分类号: C07K16/18
CPC分类号: C07K16/18 , C07K2317/32 , C07K2317/55 , C07K2317/565 , C07K2317/92
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公开(公告)号:EP4410315A3
公开(公告)日:2024-10-30
申请号:EP24170644.9
申请日:2014-12-17
申请人: GENENTECH, INC.
发明人: CHEN, Xiaocheng , DENNIS, Mark S. , EBENS, Allen J. Jr , JUNTTILA, Teemu T. , KELLEY, Robert F. , MATHIEU, Mary A. , SUN, Liping L.
摘要: The disclosure provides anti-cluster of differentiation 3 (CD3) antibodies and methods of using the same.
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公开(公告)号:EP4410315A2
公开(公告)日:2024-08-07
申请号:EP24170644.9
申请日:2014-12-17
申请人: GENENTECH, INC.
发明人: CHEN, Xiaocheng , DENNIS, Mark S. , EBENS, Allen J. Jr , JUNTTILA, Teemu T. , KELLEY, Robert F. , MATHIEU, Mary A. , SUN, Liping L.
IPC分类号: A61K47/68
CPC分类号: C07K16/2827 , C07K16/283 , C07K2317/3320130101 , C07K2317/3420130101 , C07K2317/7320130101 , A61K47/6881 , C07K16/2809 , C07K16/2887 , C07K16/30 , A61K31/573 , C07K2317/9220130101 , C07K2317/2420130101 , A61K2039/50520130101 , C07K16/32 , A61P1/04 , A61P13/12 , A61P17/00 , A61P17/06 , A61P19/02 , A61P21/04 , A61P25/00 , A61P25/02 , A61P27/02 , A61P29/00 , A61P35/00 , A61P35/02 , A61P37/00 , A61P37/02 , A61P37/04 , A61P37/06 , A61P43/00 , A61P7/00 , A61P7/04 , A61P9/00 , A61P9/08 , A61P3/10
摘要: The disclosure provides anti-cluster of differentiation 3 (CD3) antibodies and methods of using the same.
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公开(公告)号:EP3083689B1
公开(公告)日:2020-05-27
申请号:EP14828608.1
申请日:2014-12-17
申请人: Genentech, Inc.
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公开(公告)号:EP2097455B1
公开(公告)日:2014-10-22
申请号:EP07868632.6
申请日:2007-10-31
申请人: Genentech, Inc.
发明人: WU, Herren , SINGH, Sanjaya , FUNG, Sek, Chung , AN, Ling-ling , LOWMAN, Henry B. , KELLEY, Robert F.
CPC分类号: C07K16/18 , A61K2039/505 , C07K16/40 , C07K2317/24 , C07K2317/50 , C07K2317/54 , C07K2317/55 , C07K2317/56 , C07K2317/565 , C07K2317/76 , C07K2317/92
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公开(公告)号:EP2558496A1
公开(公告)日:2013-02-20
申请号:EP11769579.1
申请日:2011-04-14
申请人: Genentech, Inc.
IPC分类号: C07K16/18 , A61K39/395
CPC分类号: C07K16/18 , C07K14/4702 , C07K2317/24 , C07K2317/30 , C07K2317/55 , C07K2317/56 , C07K2317/565 , C07K2317/92 , C12N15/1037 , G01N33/68 , G01N2333/4703 , G01N2440/36
摘要: The invention provides anti-polyubiquitin antibodies and methods of using the same.
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