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11.
公开(公告)号:EP1809673B1
公开(公告)日:2012-11-28
申请号:EP05810858.0
申请日:2005-10-03
申请人: Genentech, Inc.
发明人: KIRCHHOFER, Daniel, K. , WU, Yan
IPC分类号: C07K16/40 , A61P35/00 , A61K39/395 , C12N9/64
CPC分类号: C07K16/22 , C07K16/32 , C07K16/40 , C07K2317/21 , C07K2317/24 , C07K2317/54 , C07K2317/565 , C07K2317/76 , C07K2317/92
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12.
公开(公告)号:EP2468772A2
公开(公告)日:2012-06-27
申请号:EP11195410.3
申请日:2007-03-16
申请人: GENENTECH, INC.
发明人: YE, Weilan , SCHMIDT, Maike , HONGO, Jo-Anne , WU, Yan
CPC分类号: C07K16/22 , A61K2039/505 , A61K2039/507 , C07K2317/56 , C07K2317/565 , C07K2317/73
摘要: The invention provides anti-EGFL7 antibodies, and compositions comprising and methods of using these antibodies.
摘要翻译: 本发明提供了抗EGFL7抗体,以及组合物和使用这些抗体的方法。
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公开(公告)号:EP2291405A1
公开(公告)日:2011-03-09
申请号:EP09747445.6
申请日:2009-05-13
申请人: Genentech, Inc.
IPC分类号: C07K16/28 , A61K39/395 , A61P25/28
CPC分类号: C07K16/2803 , C07K2317/55 , C07K2317/56 , C07K2317/565 , C07K2317/76
摘要: The present disclosure relates generally to neural development and neurological disorders. The disclosure specifically concerns identification of novel modulators of the myelin-associated inhibitory system and various uses of the modulators so identified.
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公开(公告)号:EP2032604A2
公开(公告)日:2009-03-11
申请号:EP07868300.0
申请日:2007-06-06
申请人: Genentech, Inc.
发明人: YAN, Minhong , WU, Yan
IPC分类号: C07K16/22
CPC分类号: A61K45/06 , A61K2039/505 , A61K2039/507 , C07K16/22 , C07K2317/24 , C07K2317/33 , C07K2317/565 , C07K2317/73 , C07K2317/74 , C07K2317/76 , C07K2317/92
摘要: The invention provides anti-DLL4 antibodies, and compositions comprising and methods of using these antibodies.
摘要翻译: 本发明提供了抗DLL4抗体,以及包含这些抗体的方法和使用这些抗体的方法。
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公开(公告)号:EP1989231A2
公开(公告)日:2008-11-12
申请号:EP07868188.9
申请日:2007-03-21
申请人: Genentech, Inc.
IPC分类号: C07K16/22 , C07K16/28 , A61K39/395 , G01N33/573 , G01N33/50 , G01N33/68 , A61P35/00
CPC分类号: A61K39/3955 , A61K45/06 , A61K51/1093 , A61K2039/505 , A61K2039/507 , C07K16/22 , C07K16/2842 , C07K2317/73 , C07K2317/76 , C07K2317/92 , G01N33/74
摘要: The present invention relates to the use of VEGF antagonists and alpha5beta1 antagonists for treating cancer and inhibiting angiogenesis and/or vascular permeability, including inhibiting abnormal angiogenesis in diseases. The present invention also relates to use of a VEGFR agonists and alpha5beta1 agonists to promote angiogenesis and vascular permeability. The present invention also relates to new anti-alpha5beta1 antibodies, compositions and kits comprising them and methods of making and using them.
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公开(公告)号:EP1984404A2
公开(公告)日:2008-10-29
申请号:EP07797130.7
申请日:2007-02-12
申请人: Genentech, Inc.
发明人: DIXIT, Vishva , KAYAGAKI, Nobuhiko , WU, Yan
IPC分类号: C07K16/28 , G01N33/564 , G01N33/569 , G01N33/574 , G01N33/68
CPC分类号: G01N33/6893 , A01K67/0276 , A01K2217/075 , A01K2227/105 , A01K2267/03 , C07K14/70575 , C07K16/2878 , C07K2317/24 , C07K2317/54 , C07K2317/565 , C07K2317/75 , C07K2317/92 , C12N15/8509 , G01N33/564 , G01N33/56972 , G01N33/57492 , G01N2800/104 , G01N2800/24
摘要: Anti-RELT monoclonal antibodies, and methods for using the antibodies, are provided. Methods of using RELT polypeptides and nucleic acids in modulating immune cell development and in modulating cytokine production are also provided.
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公开(公告)号:EP3191518B1
公开(公告)日:2020-01-15
申请号:EP15767037.3
申请日:2015-09-11
申请人: Genentech, Inc.
发明人: LEONG, Steven R. , POLSON, Andrew , POLAKIS, Paul , WU, Yan , LIANG, Wei-Ching , FIRESTEIN, Ron
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公开(公告)号:EP3080164B1
公开(公告)日:2019-01-16
申请号:EP14824269.6
申请日:2014-12-12
申请人: Genentech, Inc.
发明人: YU, Shang-Fan , LIANG, Wei-Ching , WU, Yan , LEONG, Steven , POLSON, Andrew
IPC分类号: C07K16/28 , A61K39/395 , A61P35/02
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公开(公告)号:EP3353210A2
公开(公告)日:2018-08-01
申请号:EP16775058.7
申请日:2016-09-23
发明人: GROGAN, Jane, L. , JOHNSTON, Robert, J. , WU, Yan , LIANG, Wei-Ching , LUPARDUS, Patrick , YADAV, Mahesh , SESHASAYEE, Dhaya , HAZEN, Meredith
CPC分类号: C07K16/28 , A61K38/177 , A61K39/39558 , A61K45/06 , A61K2039/505 , A61K2039/507 , C07K16/2818 , C07K16/2827 , C07K16/2878 , C07K16/3061 , C07K2317/24 , C07K2317/33 , C07K2317/34 , C07K2317/55 , C07K2317/56 , C07K2317/567 , C07K2317/70 , C07K2317/75 , C07K2317/76 , C07K2317/90 , C07K2317/92 , C07K2317/94 , Y02A50/466
摘要: The invention provides anti-TIGIT (T-cell immunoreceptor with Ig and ITIM domains) antibodies and methods of using the same.
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公开(公告)号:EP2414395A1
公开(公告)日:2012-02-08
申请号:EP10711526.3
申请日:2010-03-31
发明人: ELKINS, Kristi , POLSON, Andrew , EBENS, Allen , ADAMS, Camelia , ZHENG, Bing , JUNUTULA, Jagath, R. , HONGO, Jo-anne , WU, Yan
IPC分类号: C07K16/28 , A61K39/395 , A61P35/02 , C12N15/13 , C12N5/20 , C07K19/00 , G01N33/574
CPC分类号: A61K39/3955 , A61K31/69 , A61K39/395 , A61K45/06 , A61K2039/505 , C07K16/283 , C07K2317/24 , C07K2317/92 , A61K2300/00
摘要: The present invention is directed to compositions of matter useful for the treatment of hematopoietic tumor in mammals and to methods of using those compositions of matter for the same.
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