-
公开(公告)号：EP2283351A1
公开(公告)日：2011-02-16
申请号：EP09746192.5
申请日：2009-05-04
IPC分类号： G01N27/74
CPC分类号： G01N27/74 , G01R33/091
摘要： In an embodiment, an oxygen sensor comprises a giant magnetoresistance device (10), and a magnetic field generator (14, 14a, 14b) arranged to generate a magnetic field (12, 12a, 12b) overlapping the giant magnetoresistance device and an examination region (20). A component (Bx) of the magnetic field detected by the giant magnetoresistance device is dependent upon an oxygen concentration in the examination region. In an embodiment, a chip (40) includes one or more electrically conductive traces (14a, 14b) disposed on or in the chip and a giant magnetoresistance device (10) disposed on or in the chip such that electrical current flowing in the trace or traces generates a magnetic field (12a, 12b) that overlaps the magnetic field sensor, said magnetic field being perturbed (Bx) by ambient oxygen (24) such that a signal output by the magnetic field sensor indicates ambient oxygen concentration.
-
公开(公告)号：EP2018560A2
公开(公告)日：2009-01-28
申请号：EP07735629.3
申请日：2007-04-24
发明人： NIEUWENHUIS, Jeroen Hans , VAN ZON, Hans , KAHLMAN, Josephus Arnoldus Henricus Maria , VEEN, Jeroen , DE BOER, Bart Michiel , JANSEN, Theodorus Petrus Henricus Gerardus
IPC分类号： G01N33/543 , G01N35/00
CPC分类号： G01R33/093 , B82Y25/00 , G01N27/745 , G01R33/1269
摘要： The invention relates to a method and a magnetic sensor device for the determination of the concentration of target particles (2) in a sample fluid, wherein the amount of the target particles (2) in a sensitive region (14) is observed by sampling measurement signals with associated sensor units (10a-10d). The target particles (2) may optionally be bound to binding sites (3) in the sensitive region, and a parametric binding curve, e.g. a Langmuir isotherm, may be fitted to the sampled measurement signals to determine the desired particle concentration in the sample. Moreover, parameters like the sampling rate and the size of the sensitive region (14) can be dynamically fitted during the ongoing sampling process to improve the signal-to-noise ratio. In another embodiment of the invention, single events corresponding to the movement of target particles into, out of, or within the sensitive region are detected and counted.
-
公开(公告)号：EP2549926A1
公开(公告)日：2013-01-30
申请号：EP11716043.2
申请日：2011-03-16
发明人： VEEN, Jeroen , JANSEN, Theodorus, Petrus, Henricus, Gerardus , FOKKENROOD, Steven, Antonie, Willem
IPC分类号： A61B5/1455
CPC分类号： A61B5/14552
摘要： The invention relates to a method of and device for monitoring a vital parameter of a patient by emitting light onto tissue of the patient with at least one light source (1, 2) and collecting light which is transmitted through the tissue and/or which is reflected from the tissue. The emitted light is multiplexed according to a predefined multiplexing scheme having a plurality of multiplexing channels, and the collected light is detected according to the predefined multiplexing scheme, resulting in a plurality of detection channels (16, 17, 18, 19). At least one of the multiplexing channels is arranged to be a dark multiplexing channel for which no light is emitted by the at least one light source (1, 2), resulting in a dark detection channel (19), and the signal of this dark detection channel (19) is used for generating a reference signal for reducing interference in the signal of at least one of the other detection channels (16, 17, 18). In this way a versatile and reliable possibility of monitoring a vital parameter of a patient with a high signal-to-interference ratio is provided.
-
公开(公告)号：EP2208045B1
公开(公告)日：2011-06-15
申请号：EP08841093.1
申请日：2008-10-21
发明人： VERSCHUREN, Coen, A. , KAHLMAN, Josephus, A., H., M. , IMMINK, Albert, H., J. , MEGENS, Mischa , VEEN, Jeroen , DE BOER, Bart, M. , JANSEN, Theodorus, P., H., G.
IPC分类号： G01N15/06
CPC分类号： G01N15/06 , G01N15/0656 , G01N2015/0693 , G01R33/1269
摘要： The invention relates to a sensor device(100) and a method for the determination of the amount of target particles(1) at a contact surface(112) adjacent to a sample chamber(2). Target particles(1) in the sample chamber are detected by a sensor element(SE) and at least one corresponding sensor-signal (s, s') is provided. An evaluation unit(EU) then determines the amount of target particles(1) in a first zone(Z1) immediately at the contracts surface(112) and a second zone(Z2) a distance(z) away from the contact surface based on this sensor-signal. In an optical measurement approach, frustrated total internal reflection taking place under different operating conditions (e.g. wavelength, angle of incidenceq) may be used to extract information about the first and second zones(Z1, Z2). In a magnetic measurement approach, different magnetic excitation fields may be used to excite magnetic target particles differently inthe first and second zone(Z2). Moreover, the temporalcourse of a sensor-signal(s, s') can be evaluated, particularly with respect to stochastic movements ofthe target particles(1).
-
公开(公告)号：EP2095122A2
公开(公告)日：2009-09-02
申请号：EP07859385.2
申请日：2007-12-14
IPC分类号： G01N33/543 , G01R33/09 , G01R33/12
CPC分类号： G01R33/093 , B82Y25/00 , G01R33/1269
摘要： The invention relates to a magnetic sensor device (100) comprising a magnetic field generator (1) driven with an excitation current of a first frequency (f1) and a magnetic sensor element (e.g. a GMR sensor (2)) driven with a sensor current (I2) of a second frequency (f2) for measuring reaction fields (HB) generated by magnetized particles (3). In an associated evaluation unit (10), a reference component (uQ) of the measurement signal (uGMR) is separated that depends on the excitation current (I1) and the sensor current (I2) but not on the presence of magnetized particles (3). The reference component (uQ) may particularly be produced by a combination of the self- magnetization (H2) of the magnetic sensor element (2) and cross-talk related currents. The reference component (uQ) may be isolated based on its phase with respect to a particle-dependent component of the measurement signal (uGMR) or based on its scaling with one of the current frequencies. Monitoring of the reference component (uQ) reveals variations in operating conditions, for example in the sensor gain, that can be used to calibrate the measurement results.
-
公开(公告)号：EP1938084A2
公开(公告)日：2008-07-02
申请号：EP06809445.7
申请日：2006-09-29
发明人： KAHLMAN, Josephus Arnoldus Henricus Maria , VEEN, Jeroen , DE BOER, Bart Michiel , JANSEN, Theodorus Petrus Henricus Gerardus
IPC分类号： G01N15/06
CPC分类号： G01R33/09 , B82Y25/00 , G01N15/0656 , G01N27/745 , G01R33/093 , G01R33/12 , G01R33/1269
摘要： The invention relates to a magnetic sensor device (10) comprising wires (11, 13) for the generation of a magnetic field with a first frequency f1 a GMR sensor (12) operated with an input current of a second frequency f2, and a demodulator (26) operated at a third frequency f3. In order to avoid signal corruption by phase noise and to improve the signal-to-noise ratio, the first, second and third frequencies are derived by a supply unit (121) from a common reference frequency fref. Said derivation may for example be achieved with the help of digital frequency dividers. Furthermore, phase detectors (PD1, PD2) may be used in a feedback control loop to assure predetermined relations between the phases of the three frequencies. In another embodiment of the invention, the phase and/or amplitude of a model signal, which is used to process a desired signal component in the output of the sensor, is tracked by an adaptation algorithm, for example a gradient descent.
-
-
-
-
-
搜索结果
16 条记录 (耗时 0.011 秒)
