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公开(公告)号：EP3227264A2
公开(公告)日：2017-10-11
申请号：EP15828557.7
申请日：2015-12-03
发明人： ZHOU, Wenjun , GEE, Kyle , TENNICO, Yolanda , SLADE, Peter , KANG, Hee Chol , KHAN, Shaheer , EVANS, Brian , STRAY, James
IPC分类号： C07D261/00 , G01N33/58
摘要： The present disclosure is directed dye compounds containing a hydrazinyl substituent and optionally, one or more negatively charged groups, such as sulfonate, phosphate, phosphonate, and/or carboxylate groups and dye compounds containing an aminooxy substitutent. The compounds are useful in the detection of analytes containing aldehyde and ketone groups, including, for example, glycans.
摘要翻译： 本公开内容涉及含有肼基取代基和任选地一个或多个带负电基团（例如磺酸根，磷酸根，膦酸根和/或羧酸根基团）和含有氨氧基取代基的染料化合物的染料化合物。 这些化合物可用于检测含有醛和酮基的分析物，包括例如聚糖。
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公开(公告)号：EP2663639B1
公开(公告)日：2017-09-13
申请号：EP12757380.6
申请日：2012-01-13
发明人： XU, Tom , TRINH, Christopher , BORNARTH, Carole , EVANS, Brian , RATH, Mousumi , TRAN, Kathy
CPC分类号： C07H21/02 , C12N15/1006 , C12Q1/6809 , C12Q1/6834 , C12Q1/6876 , C12Q2600/178 , C12Q2525/207 , C12Q2563/149
摘要： Method and compositions and kits for isolation, identification, and quantification of miRNAs and other small RNAs, including but not limited to, siRNAs, mRNAs, and snRNAs are disclosed. Methods of diagnosing a disease or its progression are also disclosed.
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公开(公告)号：EP2663639A2
公开(公告)日：2013-11-20
申请号：EP12757380.6
申请日：2012-01-13
发明人： XU, Tom , TRINH, Christopher , BORNARTH, Carole , EVANS, Brian , RATH, Mousumi , TRAN, Kathy
CPC分类号： C07H21/02 , C12N15/1006 , C12Q1/6809 , C12Q1/6834 , C12Q1/6876 , C12Q2600/178 , C12Q2525/207 , C12Q2563/149
摘要： Method and compositions and kits for isolation, identification, and quantification of miRNAs and other small RNAs, including but not limited to, siRNAs, mRNAs, and snRNAs are disclosed. Methods of diagnosing a disease or its progression are also disclosed.
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