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11.发明公开MONOACYLGLYCEROLS AND FAT-SOLUBLE NUTRIENTS FOR USE IN THE TREATMENT OF MALABSORPTION HAVING A NON-MECHANICAL BASIS 审中-公开甘油一酯和脂溶性营养素USE IN吸收问题的诊治依据其他比机械
公开(公告)号：EP3062788A1
公开(公告)日：2016-09-07
申请号：EP14795982.9
申请日：2014-10-27
申请人： Nestec S.A.
IPC分类号： A61K31/232 , A61P3/02 , A61K31/07 , A61K31/355 , A61K31/593
CPC分类号： A61K31/232 , A61K31/015 , A61K31/07 , A61K31/355 , A61K31/593 , A61K2300/00
摘要： Compositions comprising monoacylglycerols (MAG), such as sn-1(3) MAG, and further comprising fat-soluble nutrients, such as fat-soluble vitamins and carotenoids, are administered to an individual having or at risk of malabsorption having a non-mechanical basis, such as malabsorption associated with chronic liver diseases, bacterial overgrowth in the small intestine, defective enterocyte functions, lymphatic disorders, celiac disease, Crohn's disease, or Zollinger-Ellison syndrome. The compositions and the methods of using the compositions enhance absorption of fatty acids and the fat-soluble nutrients to address nutritional deficiencies due to malabsorption having a non-mechanical basis.
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12.发明公开MONOACYLGLYCEROLS FOR USE IN THE TREATMENT OF MALABSORPTION HAVING A MECHANICAL BASIS 审中-公开甘油一酯用于与机构基座吸收问题的处理
公开(公告)号：EP3062786A1
公开(公告)日：2016-09-07
申请号：EP14795980.3
申请日：2014-10-27
申请人： Nestec S.A.
IPC分类号： A61K31/232 , A61P3/02
CPC分类号： A61K31/232
摘要： Compositions comprising monoacylglycerols (MAG), such as sn-1(3) MAG, are administered to an individual having or at risk of malabsorption having a mechanical basis, such as malabsorption associated with a biliary fistula, a biliary obstruction, or short bowel syndrome from bowel surgery (resection) or bariatric surgery. Preferably the compositions are administered concurrently with fat-soluble nutrients. The compositions and the methods of using the compositions enhance absorption of fatty acids and fat-soluble nutrients, such as fat-soluble vitamins and carotenoids, to address nutritional deficiencies due to malabsorption having a mechanical basis, such as malabsorption associated with a biliary fistula, a biliary obstruction, or short bowel syndrome from bowel surgery (resection) or bariatric surgery.
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13.发明公开LONG-CHAIN POLYUNSATURATED FATTY ACIDS (LC-PUFA) IN MATERNAL NUTRITION DURING PREGNANCY AND LACTATION 审中-公开长链多不饱和脂肪酸（LC-PUFA）中的母亲食物期间怀孕和哺乳
公开(公告)号：EP2262382A1
公开(公告)日：2010-12-22
申请号：EP09727695.0
申请日：2009-03-30
申请人： Nestec S.A.
CPC分类号： A23L33/16 , A23L33/12 , A23L33/135 , A23L33/15 , A23L33/40 , A23V2002/00 , A23V2250/1868
摘要： The present invention relates in general to maternal food compositions. In particular, the present invention relates to maternal food compositions comprising LC-PUFA and their uses. Embodiments of the present invention relate to maternal food compositions comprising a source of lipids, wherein the source of lipids includes at least one LC-PUFA in the form selected from the group consisting of phospholipids (PL), phosphotidylcholine (PC), phosphatidylethanolamine (PE), N-Acylphosphatidylethanolamine (NAPE), phosphatidylinositol (Pl), phosphatidylserine (PS) or their lyso derivatives and their uses in brain development and eye development of neonates.
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14.发明公开NUTRITIONAL COMPOSITIONS COMPRISING SN-1 (3) MONOACYLGLYCEROLS FOR USE IN THE TREATMENT OF MALABSORPTION OR MALDIGESTION IN INFANTS OR YOUNG CHILDREN 审中-公开包含SN-1（3）单乙酰甘油的营养组合物用于治疗婴儿或幼儿中的吸入性疾病或马化产物
公开(公告)号：EP3212181A1
公开(公告)日：2017-09-06
申请号：EP15781655.4
申请日：2015-10-19
申请人： Nestec S.A.
IPC分类号： A61K31/232 , A23L33/12 , A23L33/00 , A61P3/02
CPC分类号： A23L33/40 , A23L33/12 , A23L33/30 , A23V2002/00 , A61K31/232
摘要： The present invention refers to nutritional composition comprising sn-1(3) monoacylglycerols for use in the treatment or prevention of maldigestion and/or malabsorption in an infant or young child. It also refers to a nutritional composition comprising sn-1(3) monoacylglycerols for use to increase lipid (e.g. fatty acids) absorption/delivery and/or to increase the energy or the mineral bioavailability in an infant or young child. The infant or young child may have a gut immaturity and/or a reduced enteral feeding tolerance. They may also be pretermand/or low birth weight.
摘要翻译： 本发明涉及包含sn-1（3）单酰基甘油的营养组合物，用于治疗或预防婴儿或幼儿的消化不良和/或吸收不良。其还涉及包含sn-1（3）单酰基甘油 用于增加婴儿或幼儿的脂质（例如脂肪酸）吸收/递送和/或增加能量或矿物质生物利用度。婴幼儿可能具有肠道不成熟和/或肠内喂养耐受性降低。 他们也可能是pretermand /或低出生体重。
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15.发明公开NUTRITIONAL COMPOSITIONS COMPRISING SN-1(3) MONOACYLGLYCEROLS FOR USE IN THE TREATMENT OF GROWTH DELAY IN INFANTS OR CHILDREN 审中-公开包含SN-1（3）单乙酰甘油的营养组合物用于治疗婴儿或儿童的生长迟缓
公开(公告)号：EP3212180A1
公开(公告)日：2017-09-06
申请号：EP15781654.7
申请日：2015-10-19
申请人： Nestec S.A.
IPC分类号： A61K31/232 , A23L33/12 , A23L33/00 , A61P3/02
CPC分类号： A61K31/232 , A23L33/12 , A23L33/40
摘要： The present invention refers to nutritional composition comprising sn-1(3) monoacylglycerols for use in the prevention/treatment of growth delay and/or in the promotion of growth in an infant or in a child like a young child, such as preterm and/or low birth weight infants.
摘要翻译： 本发明涉及包含sn-1（3）单酰基甘油的营养组合物，其用于预防/治疗生长迟缓和/或促进婴儿或儿童如幼儿的生长，如早产和/ 或低出生体重的婴儿。
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16.发明公开SYNTHETIC MILK COMPOSITIONS FOR INFANTS LESS THAN THREE MONTHS OLD AND FOR INFANTS AND CHILDREN MORE THAN THREE MONTHS FOR ENSURING OPTIMAL GROWTH AND PREVENTING OBESITY 审中-公开对于不太涨幅超过三个月大的婴儿和儿童合成MILK组合物，以确保肥胖的最佳生长和预防
公开(公告)号：EP3079770A1
公开(公告)日：2016-10-19
申请号：EP14761640.3
申请日：2014-09-09
申请人： Nestec S.A.
发明人： DE CASTRO, Carlos Antonio , CRUZ-HERNANDEZ, Cristina , DESTAILLATS, Frederic , GIUFFRIDA, Francesca , THAKKAR, Sagar , MUKHERJEE, Rajat
IPC分类号： A61P3/04
摘要： The invention concerns synthetic nutritional formulations, particularly milk based compositions, for infants and children. The compositions are especially adapted to the age of the child. They are adapted to fulfill the nutritional needs of the child, ensuring balanced growth and development and thereby reducing the risk of obesity.
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17.发明公开MONOACYLGLYCEROLS FOR USE IN CONJUNCTION WITH A LIPASE INHIBITOR AND/OR DIETS LOW IN FAT AND/OR CALORIES 审中-公开用于与脂肪酶抑制剂连接甘油一酯和/或脂肪或低热量饮食
公开(公告)号：EP3062787A1
公开(公告)日：2016-09-07
申请号：EP14795981.1
申请日：2014-10-27
申请人： Nestec S.A.
IPC分类号： A61K31/232 , A61K31/365 , A61P43/00
CPC分类号： A61K31/232 , A23L33/15 , A23L33/155 , A23L33/30 , A23V2002/00 , A61K31/337 , A61K31/365 , A61K45/06 , A61K2300/00
摘要： In an embodiment, compositions comprising monoacylglycerols (MAG), such as sn-1(3) MAG, are administered with a lipase inhibitor, such as tetrahydrolipstatin, and/or with a diet low in fat and/or calories. In another embodiment, compositions comprising MAG, such as sn-1(3) MAG, are administered concurrently with a lipase inhibitor, such as tetrahydrolipstatin, and/or with fat-soluble nutrients. The compositions and the methods of using the compositions enhance absorption of fatty acids and fat-soluble nutrients such as fat-soluble vitamins and carotenoids to address nutritional deficiencies due to a weight loss diet used in association with a lipase inhibitor.
摘要翻译： ，实施例组合物，包含单酰基甘油（MAG）在,:如Sn-1（3）MAG，施用，所述脂肪酶抑制剂，如四氢里卜斯他丁检查，和/或与在脂肪和/或卡路里饮食低。 在另一个实施方式组合物，包含MAG，作为检查的sn-1（3）MAG，与脂肪酶抑制剂同时施用如四氢检查，和/或与脂溶性营养物。 的组合物和使用该组合物的方法中提高的脂肪酸和脂溶性营养物吸收：按照脂溶性维生素和类胡萝卜素，以解决营养缺乏这样由于在关联使用脂酶抑制剂的重量损失的饮食。
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