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公开(公告)号：EP0865615A1
公开(公告)日：1998-09-23
申请号：EP96939249.0
申请日：1996-12-06
申请人： Novartis AG
CPC分类号： G02B1/043 , A61L27/26 , B29C39/42 , B29C71/00 , B29L2011/0041 , C08G18/10 , C08G18/5015 , C08G18/61 , C08G18/8116 , C08G18/8175 , C08L51/085 , C08L51/08 , C08L33/00 , C08L83/04 , C08G18/48 , C08G18/63
摘要： A method of forming an ophthalmic lens suited for extended-wear periods without a clinically significant amount of corneal swelling and without substantial wearer discomfort. The lens has a balance of oxygen permeability and ion or water permeability, with the ion or water permeability being sufficient to provide good on-eye movement, such that a good tear exchange occurs between the lens and the eye. The manufacturing method requires the oxygen concentration of the polymerizable material to be low enough to produce a lens having a high ion permeability. A preferred oxygen concentration in the polymerizable material is a concentration below 200 ppm.
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12.发明公开POLYSILOXANE-COMPRISING PERFLUOROALKYL ETHERS, AND THE PREPARATION AND USE THEREOF 失效全氟烷含聚硅氧烷及其制备方法和用途
公开(公告)号：EP0820601A1
公开(公告)日：1998-01-28
申请号：EP96908111.0
申请日：1996-03-22
申请人： Novartis AG
CPC分类号： B29D11/00076 , A61L27/26 , A61L27/34 , B05D1/62 , B29C39/42 , B29C71/00 , B29L2011/0041 , C08G18/10 , C08G18/4833 , C08G18/5015 , C08G18/61 , C08G18/672 , C08G18/8116 , C08G18/8175 , G02B1/043 , Y10S525/903 , Y10S525/936 , Y10S525/937 , Y10T428/3154 , Y10T428/31544 , Y10T428/31663 , C08L51/085 , C08L51/08 , C08L83/04 , C08L33/00 , C08L39/06 , C08G18/63 , C08G18/48
摘要： The present invention describes a free-radical-polymerizable macromer of the formula (I) based on an unsubstituted or symmetrically substituted perfluoroalkyl ether; a polymer comprising the product of the polymerization of a novel macromer; alone or together with at least one vinylic comonomer; a process for the preparation of a macromer and a polymer; mouldings, contact lenses, corneal implants and biomedical articles made from a polymer; and articles coated with a macromer of the formula (I) or a polymerization product thereof.
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公开(公告)号：EP0865326B1
公开(公告)日：2006-08-16
申请号：EP96942292.2
申请日：1996-12-02
申请人： Novartis AG , Novartis Pharma GmbH
发明人： LOHMANN, Dieter , CHABRECEK, Peter , HÖPKEN, Jens
CPC分类号： A61F2/145 , A61F2/16 , A61L27/26 , A61L27/34 , B05D1/62 , B29C39/42 , B29C71/00 , B29L2011/0041 , C08G18/10 , C08G18/4833 , C08G18/5015 , C08G18/61 , C08G18/672 , C08G18/8116 , C08G18/8175 , G02B1/043 , G02C7/02 , Y10S525/903 , Y10S525/936 , Y10S525/937 , A61L27/18 , C08L83/04 , C08L39/06 , C08L33/26 , C08L33/06 , C08L33/00 , C08L51/08 , C08L51/085 , C08G18/48 , C08G18/63
摘要： The present invention relates to coated articles wherein the polymer chains of the coating are obtainable by after-glow plasma-induced polymerization of a monomer under specific plasma conditions. The invention further relates to a method for the production of articles coated with a polymer of said features.
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公开(公告)号：EP1084428A1
公开(公告)日：2001-03-21
申请号：EP99920810.1
申请日：1999-04-28
发明人： CHABRECEK, Peter , HÖPKEN, Jens , LOHMANN, Dieter
IPC分类号： G02B1/04 , C08J7/16 , C08J7/18 , C08F290/00
CPC分类号： G02B1/043 , C08F290/00 , C08F290/04 , C08J7/16 , Y10T428/31551 , Y10T428/31692 , Y10T428/31855
摘要： The invention relates to novel composite materials comprising (a) an inorganic or organic bulk material having covalently bound to its surface initiator moieties for radical polymerization; and (b) a hydrophilic surface coating obtainable by applying one or more different ethylenically unsaturated hydrophilic macromonomers of formula (1) as outlined in the claims to the bulk material surface provided with the initiator radicals and polymerizing said macromonomers. The composite materials of the invention have desirable characteristics regarding adherence to the substrate, durability, hydrophilicity, wettability, biocompatibility and permeability and are thus useful for the manufacture of biomedical articles such as ophthalmic devices.
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公开(公告)号：EP1024945A1
公开(公告)日：2000-08-09
申请号：EP98950096.2
申请日：1998-09-30
CPC分类号： B29D11/00432 , B29D11/00125 , G02B1/043
摘要： A method of making an ophthalmic lens comprising the steps of: preparing a polymerizable composition comprising excessive oxygen content; contacting the polymerizable composition with a gas that is inert or substantially inert to the polymerizable composition, and deoxygenating or partially deoxygenating the polymerizable composition; conveying all or part of the polymerizable composition to an ophthalmic lens mold; polymerizing all or part of the polymerizable composition and obtaining a polymeric ophthalmic lens, and the lens produced by such process.
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16.发明授权POLYSILOXANE-COMPRISING PERFLUOROALKYL ETHERS, AND THE PREPARATION AND USE THEREOF 失效全氟烷含聚硅氧烷及其制备方法和用途
公开(公告)号：EP0820601B1
公开(公告)日：1999-12-22
申请号：EP96908111.6
申请日：1996-03-22
CPC分类号： B29D11/00076 , A61L27/26 , A61L27/34 , B05D1/62 , B29C39/42 , B29C71/00 , B29L2011/0041 , C08G18/10 , C08G18/4833 , C08G18/5015 , C08G18/61 , C08G18/672 , C08G18/8116 , C08G18/8175 , G02B1/043 , Y10S525/903 , Y10S525/936 , Y10S525/937 , Y10T428/3154 , Y10T428/31544 , Y10T428/31663 , C08L51/085 , C08L51/08 , C08L83/04 , C08L33/00 , C08L39/06 , C08G18/63 , C08G18/48
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公开(公告)号：EP0868457A1
公开(公告)日：1998-10-07
申请号：EP96943907.0
申请日：1996-12-10
申请人： Novartis AG
CPC分类号： C08G18/61 , G02B1/043 , Y10T428/31663 , C08L75/04
摘要： The present invention describes a polymer and a precursor thereof; a prepolymer made essentially from a macromer that is cross-linked, for example, via its free hydroxy groups with a polyisocyanate, the macromer being made essentially from a polysiloxane and a polyol component; processes for the production of such prepolymers and polymers; the use of such polymers, for example, as artificial corneas, as moulded articles, especially as contact lens material; also the use of a prepolymer or polymer for coating surfaces, especially functionalised polymer surfaces.
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公开(公告)号：EP0865326A1
公开(公告)日：1998-09-23
申请号：EP96942292.0
申请日：1996-12-02
申请人： Novartis AG
发明人： LOHMANN, Dieter , CHABRECEK, Peter , HÖPKEN, Jens
IPC分类号： G02C7 , A61L27 , B05D7 , B29C39 , C08G18 , C08J7 , C09D5 , C09D133 , C09D139 , G02B1 , B29C71
CPC分类号： A61F2/145 , A61F2/16 , A61L27/26 , A61L27/34 , B05D1/62 , B29C39/42 , B29C71/00 , B29L2011/0041 , C08G18/10 , C08G18/4833 , C08G18/5015 , C08G18/61 , C08G18/672 , C08G18/8116 , C08G18/8175 , G02B1/043 , G02C7/02 , Y10S525/903 , Y10S525/936 , Y10S525/937 , A61L27/18 , C08L83/04 , C08L39/06 , C08L33/26 , C08L33/06 , C08L33/00 , C08L51/08 , C08L51/085 , C08G18/48 , C08G18/63
摘要： The present invention relates to coated articles wherein the polymer chains of the coating are obtainable by after-glow plasma-induced polymerization of a monomer under specific plasma conditions. The invention further relates to a method for the production of articles coated with a polymer of said features.
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