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公开(公告)号：EP0819258A1
公开(公告)日：1998-01-21
申请号：EP96908116.0
申请日：1996-03-22
发明人： NICOLSON, Paul, Clement , BARON, Richard, Carlton , CHABRECEK, Peter , COURT, John , DOMSCHKE, Angelika , GRIESSER, Hans, Jörg , HO, Arthur , HÖPKEN, Jens , LAYCOCK, Bronwyn, Glenice , LIU, Qin , LOHMANN, Dieter , MEIJS, Gordon, Francis , PAPASPILIOTOPOULOS, Eric , RIFFLE, Judy, Smith , SCHINDHELM, Klaus , SWEENEY, Deborah , TERRY, Wilson, Leonard, Jr. , VOGT, Jürgen , WINTERTON, Lynn, Cook
IPC分类号： G02C7 , A61L27 , B29C39 , B29D11 , C08F290 , C08G18 , C08J5 , C08L33 , C08L83 , G02B1 , B29C71
CPC分类号： G02C7/049 , A61L27/26 , A61L27/34 , A61L2430/16 , B05D1/62 , B29C39/42 , B29C71/00 , B29D11/00076 , B29L2011/0041 , C08G18/10 , C08G18/4833 , C08G18/5015 , C08G18/61 , C08G18/672 , C08G18/8116 , C08G18/8175 , G02B1/043 , Y10S525/903 , Y10S525/936 , Y10S525/937 , C08L51/085 , C08L51/08 , C08L33/00 , C08L83/04 , C08L39/06 , C08G18/63 , C08G18/48
摘要： An ophthalmic lens is disclosed which is suited for extended-wear periods of at least one day on the eye without a clinically significant amount of corneal swelling and without substantial wearer discomfort. The lens has a balance of oxygen permeability and ion or water permeability, with the ion or water permeability being sufficient to provide good on-eye movement, such that a good tear exchange occurs between the lens and the eye. A preferred lens is a copolymerization product of an oxyperm macromer and an ionoperm monomer. The invention encompasses extended wear contact lenses, which include a core having oxygen transmission and ion transmission pathways extending from the inner surface to the outer surface.
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公开(公告)号：EP1200499A1
公开(公告)日：2002-05-02
申请号：EP00953125.2
申请日：2000-07-31
发明人： HÖPKEN, Jens , LOHMANN, Dieter
IPC分类号： C08F290/04 , C08G81/02 , G02B1/04
CPC分类号： G02B1/043 , C08F290/04 , C08G81/024 , C08L83/10 , C08L71/00
摘要： The invention relates to novel crosslinkable copolymer of formula (1) wherein the variables are as defined in the claims. The copolymers of the invention are especially useful for the manufacture of biomedical moldings, for example ophthalmic moldings such as in particular contact lenses.
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公开(公告)号：EP0819258B1
公开(公告)日：2001-09-12
申请号：EP96908116.5
申请日：1996-03-22
发明人： NICOLSON, Paul, Clement , BARON, Richard, Carlton , CHABRECEK, Peter , COURT, John , DOMSCHKE, Angelika , GRIESSER, Hans, Jörg , HO, Arthur , HÖPKEN, Jens , LAYCOCK, Bronwyn, Glenice , LIU, Qin , LOHMANN, Dieter , MEIJS, Gordon, Francis , PAPASPILIOTOPOULOS, Eric , RIFFLE, Judy, Smith , SCHINDHELM, Klaus , SWEENEY, Deborah , TERRY, Wilson, Leonard, Jr. , VOGT, Jürgen , WINTERTON, Lynn, Cook
IPC分类号： G02B1/04
CPC分类号： G02C7/049 , A61L27/26 , A61L27/34 , A61L2430/16 , B05D1/62 , B29C39/42 , B29C71/00 , B29D11/00076 , B29L2011/0041 , C08G18/10 , C08G18/4833 , C08G18/5015 , C08G18/61 , C08G18/672 , C08G18/8116 , C08G18/8175 , G02B1/043 , Y10S525/903 , Y10S525/936 , Y10S525/937 , C08L51/085 , C08L51/08 , C08L33/00 , C08L83/04 , C08L39/06 , C08G18/63 , C08G18/48
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公开(公告)号：EP1200499B1
公开(公告)日：2004-10-06
申请号：EP00953125.2
申请日：2000-07-31
申请人： Novartis AG , Novartis Pharma GmbH
发明人： HÖPKEN, Jens , LOHMANN, Dieter
IPC分类号： C08F290/04 , C08G81/02 , G02B1/04
CPC分类号： G02B1/043 , C08F290/04 , C08G81/024 , C08L83/10 , C08L71/00
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公开(公告)号：EP0868457B1
公开(公告)日：2002-09-11
申请号：EP96943907.4
申请日：1996-12-10
CPC分类号： C08G18/61 , G02B1/043 , Y10T428/31663 , C08L75/04
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公开(公告)号：EP0826158A1
公开(公告)日：1998-03-04
申请号：EP96919684.0
申请日：1996-05-07
申请人： Novartis AG
IPC分类号： G02C7 , A61F2 , A61L27 , B05D7 , B29C39 , C08F290 , C08F299 , C08G18 , C08G77 , G02B1 , B29C71
CPC分类号： B29D11/00076 , A61L27/26 , A61L27/34 , B05D1/62 , B29C39/42 , B29C71/00 , B29L2011/0041 , C08G18/10 , C08G18/4833 , C08G18/5015 , C08G18/61 , C08G18/672 , C08G18/8116 , C08G18/8175 , G02B1/043 , Y10S525/903 , Y10S525/936 , Y10S525/937 , C08L51/08 , C08L51/085 , C08L33/00 , C08L83/04 , C08L39/06 , C08G18/48 , C08G18/63
摘要： The present invention describes a polysiloxane-polyol macromer which is uninterrupted or interrupted by a bivalent structural element and furthermore carries at least one polymerizable segment on a polyol segment; a polymer comprising a polymerization product of at least one macromer according to the invention and, if appropriate, of at least one vinylic comonomer; intermediates; processes for the preparation of a macromer and a polymerization product; moldings, contact lenses, corneal implants or biomedical articles of a polymerization product; and furthermore the use of a macromer according to the invention or of a polymer prepared therefrom for coating a substrate.
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公开(公告)号：EP1084428B1
公开(公告)日：2004-11-10
申请号：EP99920810.1
申请日：1999-04-28
申请人： Novartis AG , Novartis Pharma GmbH
发明人： CHABRECEK, Peter , HÖPKEN, Jens , LOHMANN, Dieter
IPC分类号： G02B1/04 , C08J7/16 , C08J7/18 , C08F290/00
CPC分类号： G02B1/043 , C08F290/00 , C08F290/04 , C08J7/16 , Y10T428/31551 , Y10T428/31692 , Y10T428/31855
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8.发明授权AMPHIPHILIC, SEGMENTED COPOLYMER OF CONTROLLED MORPHOLOGY AND OPHTHALMIC DEVICES INCLUDING CONTACT LENSES MADE THEREFROM 失效两亲段和控制形态的共聚物; 眼科产品以及基于这些共聚物隐形眼镜
公开(公告)号：EP0907668B1
公开(公告)日：2001-09-19
申请号：EP97928246.4
申请日：1997-06-19
申请人： Novartis AG
发明人： HIRT, Thomas , LOHMANN, Dieter , HÖPKEN, Jens , LIU, Qin
IPC分类号： C08F290/02 , G02B1/04
CPC分类号： G02B1/043 , C08F290/02 , Y10S525/937
摘要： The subject matter of the present invention is an amphiphilic, segmented copolymer of controlled morphology comprising at least one segment having high oxygen permeability, at least one segment having high ion and water permeability, the segments being linked together through a non-hydrolizable bond, and at least one polymerizable unsaturated group; a process for the preparation of the copolymer; to polymeric products obtainable by further polymerizing and optionally cross-linking the amphiphilic segmented copolymer, and to mouldings, especially contact lenses and other ophthalmic devices comprising a polymeric product of the invention. In a specifically preferred embodiment, the present invention relates to a contact lens comprising a polymeric product of the invention which is suited for extended periods of wear.
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公开(公告)号：EP0826158B1
公开(公告)日：1999-09-15
申请号：EP96919684.9
申请日：1996-05-07
申请人： Novartis AG
CPC分类号： B29D11/00076 , A61L27/26 , A61L27/34 , B05D1/62 , B29C39/42 , B29C71/00 , B29L2011/0041 , C08G18/10 , C08G18/4833 , C08G18/5015 , C08G18/61 , C08G18/672 , C08G18/8116 , C08G18/8175 , G02B1/043 , Y10S525/903 , Y10S525/936 , Y10S525/937 , C08L51/08 , C08L51/085 , C08L33/00 , C08L83/04 , C08L39/06 , C08G18/48 , C08G18/63
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10.发明公开AMPHIPHILIC, SEGMENTED COPOLYMER OF CONTROLLED MORPHOLOGY AND OPHTHALMIC DEVICES INCLUDING CONTACT LENSES MADE THEREFROM 失效两亲段和控制形态的共聚物; 眼科产品以及基于这些共聚物隐形眼镜
公开(公告)号：EP0907668A1
公开(公告)日：1999-04-14
申请号：EP97928246.0
申请日：1997-06-19
申请人： Novartis AG
发明人： HIRT, Thomas , LOHMANN, Dieter , HÖPKEN, Jens , LIU, Qin
CPC分类号： G02B1/043 , C08F290/02 , Y10S525/937
摘要： The subject matter of the present invention is an amphiphilic, segmented copolymer of controlled morphology comprising at least one segment having high oxygen permeability, at least one segment having high ion and water permeability, the segments being linked together through a non-hydrolizable bond, and at least one polymerizable unsaturated group; a process for the preparation of the copolymer; to polymeric products obtainable by further polymerizing and optionally cross-linking the amphiphilic segmented copolymer, and to mouldings, especially contact lenses and other ophthalmic devices comprising a polymeric product of the invention. In a specifically preferred embodiment, the present invention relates to a contact lens comprising a polymeric product of the invention which is suited for extended periods of wear.
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