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公开(公告)号:EP2968592A2
公开(公告)日:2016-01-20
申请号:EP14729099.3
申请日:2014-03-13
申请人: Novartis AG
发明人: ETTENBERG, Seth , HAUBST, Nicole , HU, Tiancen , JENKINS, David , TOKSOZ, Engin , MOSHER, Rebecca , MEYER, Matthew John , PETROPOULOS, Konstantin
CPC分类号: C07K16/30 , A61K31/506 , A61K45/06 , A61K47/549 , A61K47/6803 , A61K47/6849 , A61K47/6879 , A61K2039/505 , C07K16/2863 , C07K16/3015 , C07K16/3023 , C07K16/303 , C07K16/3038 , C07K16/3046 , C07K16/3069 , C07K2317/21 , C07K2317/31 , C07K2317/33 , C07K2317/34 , C07K2317/52 , C07K2317/55 , C07K2317/565 , C07K2317/73 , C07K2317/732 , C07K2317/75 , C07K2317/76 , C07K2317/92 , C07K2319/00
摘要: The present invention relates to anti-FGFR2 and FGFR4 antibodies, antibody fragments, antibody drug conjugates, and their uses for the treatment of cancer.
摘要翻译: 本发明涉及抗FGFR2和FGFR4抗体,抗体片段,抗体药物缀合物,以及它们用于治疗癌症的用途。
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公开(公告)号:EP3611189A1
公开(公告)日:2020-02-19
申请号:EP19170673.8
申请日:2014-03-10
申请人: Novartis AG
发明人: DEPLAZES-LAUBER, Joelle , FRYER, Christy , HU, Tiancen , JENKINS, David , PETROPOULOS, Konstantin , THIEL, Philippe
IPC分类号: C07K16/28 , A61K39/395
摘要: The present disclosure relates to antibodies or fragments thereof that target at least one conformational epitope of a Notch 3 or mutant Notch 3 receptor; and compositions and methods of use thereof.
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公开(公告)号:EP2970479B1
公开(公告)日:2019-04-24
申请号:EP14722403.4
申请日:2014-03-10
申请人: Novartis AG
发明人: DEPLAZES-LAUBER, Joelle , FRYER, Christy , HU, Tiancen , JENKINS, David , PETROPOULOS, Konstantin , THIEL, Philippe
IPC分类号: C07K16/28 , A61K39/395
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公开(公告)号:EP2970479A2
公开(公告)日:2016-01-20
申请号:EP14722403.4
申请日:2014-03-10
申请人: Novartis AG
发明人: DEPLAZES-LAUBER, Joelle , FRYER, Christy , HU, Tiancen , JENKINS, David , PETROPOULOS, Konstantin , THIEL, Philippe
IPC分类号: C07K16/28 , A61K39/395
CPC分类号: C07K16/28 , A61K2039/505 , C07K2317/21 , C07K2317/32 , C07K2317/33 , C07K2317/34 , C07K2317/54 , C07K2317/55 , C07K2317/56 , C07K2317/565 , C07K2317/73 , C07K2317/76 , C07K2317/92 , G01N33/57484 , G01N2800/50 , G01N2800/7028
摘要: The present disclosure relates to antibodies or fragments thereof that target at least one conformational epitope of a Notch 3 or mutant Notch 3 receptor; and compositions and methods of use thereof.
摘要翻译: 本公开涉及靶向Notch 3或突变型Notch 3受体的至少一个构象表位的抗体或其片段; 及其组合物和使用方法。
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