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公开(公告)号:EP2968592A2
公开(公告)日:2016-01-20
申请号:EP14729099.3
申请日:2014-03-13
申请人: Novartis AG
发明人: ETTENBERG, Seth , HAUBST, Nicole , HU, Tiancen , JENKINS, David , TOKSOZ, Engin , MOSHER, Rebecca , MEYER, Matthew John , PETROPOULOS, Konstantin
CPC分类号: C07K16/30 , A61K31/506 , A61K45/06 , A61K47/549 , A61K47/6803 , A61K47/6849 , A61K47/6879 , A61K2039/505 , C07K16/2863 , C07K16/3015 , C07K16/3023 , C07K16/303 , C07K16/3038 , C07K16/3046 , C07K16/3069 , C07K2317/21 , C07K2317/31 , C07K2317/33 , C07K2317/34 , C07K2317/52 , C07K2317/55 , C07K2317/565 , C07K2317/73 , C07K2317/732 , C07K2317/75 , C07K2317/76 , C07K2317/92 , C07K2319/00
摘要: The present invention relates to anti-FGFR2 and FGFR4 antibodies, antibody fragments, antibody drug conjugates, and their uses for the treatment of cancer.
摘要翻译: 本发明涉及抗FGFR2和FGFR4抗体,抗体片段,抗体药物缀合物,以及它们用于治疗癌症的用途。
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公开(公告)号:EP3515446A1
公开(公告)日:2019-07-31
申请号:EP17778357.8
申请日:2017-09-18
申请人: Novartis AG
IPC分类号: A61K31/505 , A61K31/5377 , A61K45/06 , A61P35/00
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公开(公告)号:EP3389711A1
公开(公告)日:2018-10-24
申请号:EP16822542.3
申请日:2016-12-16
申请人: Novartis AG
发明人: BALKE, Nicole , CALZASCIA, Thomas , EWERT, Stefan , HUET, Heather Adkins , HARRIS, Alan , ISNARDI, Isabelle , MEYER, Matthew John , WILSON, Nicholas , XU, Fangmin , LU, Haihui
IPC分类号: A61K39/395 , C07K16/28
CPC分类号: C07K16/2803 , A61K39/395 , A61K45/06 , A61K2039/505 , A61K2039/507 , A61K2039/541 , A61K2039/545 , C07K16/28 , C07K16/283 , C07K16/2887 , C07K2317/31 , C07K2317/33 , C07K2317/34 , C07K2317/35 , C07K2317/41 , C07K2317/56 , C07K2317/565 , C07K2317/71 , C07K2317/72 , C07K2317/732 , C07K2317/76 , C07K2317/92
摘要: The present invention relates to isolated antibodies and antigen-binding fragments thereof which selectively bind human CD32b. Also provided herein are compositions comprising the antibodies or antigen-binding fragments thereof, methods of using the antibodies or antigen-binding fragments thereof, and methods of making the antibodies or antigen-binding fragments thereof.
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公开(公告)号:EP3180360A1
公开(公告)日:2017-06-21
申请号:EP15766632.2
申请日:2015-08-07
申请人: Novartis AG
发明人: BIALUCHA, Carl Uli , COLLINS, Scott , HU, Tiancen , JANATPOUR, Mary Jo , MEYER, Matthew John , DÜRR, Clemens
IPC分类号: C07K16/28 , A61K39/395 , A61P35/00 , A61K31/00
CPC分类号: C07K16/28 , A61K31/4738 , A61K45/06 , A61K47/6803 , A61K47/6849 , A61K47/6889 , A61K2039/505 , C07K2317/21 , C07K2317/34 , C07K2317/40 , C07K2317/55 , C07K2317/56 , C07K2317/73 , C07K2317/92 , G01N33/57492 , G01N2333/705 , A61K2300/00 , A61K39/395
摘要: The present invention relates to anti-CDH6 antibodies, antibody fragments, antibody drug conjugates, and their uses for the treatment of cancer.
摘要翻译: 本发明涉及抗CDH6抗体,抗体片段,抗体药物缀合物及其用于治疗癌症的用途。
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5.
公开(公告)号:EP3773586A1
公开(公告)日:2021-02-17
申请号:EP19721810.0
申请日:2019-03-29
申请人: Novartis AG
发明人: MEYER, Matthew John , WANG, Youzhen
IPC分类号: A61K31/4965 , A61K31/506 , A61K31/519 , A61P35/00
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