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公开(公告)号：EP0086502B1
公开(公告)日：1987-03-25
申请号：EP83102429.4
申请日：1980-08-14
IPC分类号： C07D253/06 , A61K31/53
CPC分类号： C07D253/075 , A61K31/53
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12.发明授权1,2,4-Triazine derivatives, process for preparing such compounds and pharmaceutical compositions containing them 失效1,2,4-三唑衍生物，制备这些化合物的方法和含有它们的药物组合物
公开(公告)号：EP0021121B1
公开(公告)日：1983-05-11
申请号：EP80103032.1
申请日：1980-05-30
发明人： Baxter, Martin George , Elphick, Albert Reginald , Miller, Alistair Ainslie , Sawyer, David Alan
IPC分类号： C07D253/06 , A61K31/53
CPC分类号： C07D253/075 , C07C51/15 , C07C51/363 , C07C255/00 , C07C281/18 , C07C63/70
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13.发明公开3,5-Diamino-1,2,4-triazine derivatives, process for preparing such compounds and pharmaceutical compositions containing them 失效3,5-二氨基-1,2,4-三嗪衍生物，用于制备这些化合物和含有它们的药物组合物。
公开(公告)号：EP0021120A1
公开(公告)日：1981-01-07
申请号：EP80103031.3
申请日：1980-05-30
发明人： Baxter, Martin George , Elphick, Albert Reginald , Miller, Alistair Ainslie , Sawyer, David Alan
IPC分类号： C07D253/06 , A61K31/53
CPC分类号： C07D253/075
摘要： The present invention provides compounds of the formula (III):
or an acid addition salt thereof, wherein R 6 , R 7 , R 9 and R 10 are each hydrogen, halogen, C 1-4 alkyl or trifluoromethyl and R 8 is chlorine or R 7 and R 8 ar linked to form a -CH=CH-CH=CH- group when one of R 6 and R 10 is other than hydrogen provided that when R 8 is chlorine R 6 , R 7 , R 9 and R 10 are not all hydrogen atoms and that any one of R 6 , R 7 , R 9 and R 10 is not chlorine when the other three groups are hydrogen. Also provided are pharmaceutical compositions containing compounds of the formula (III), the first medical use of compounds of the formula (III), a process for preparing such compounds and intermediates through which this process proceeds.
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