公开(公告)号：EP3103519A1

公开(公告)日：2016-12-14

申请号：EP15171867.3

申请日：2015-06-12

申请人： RaySearch Laboratories AB

发明人： Eriksson, Kjell

IPC分类号： A61N5/10 ,  G06F19/00

CPC分类号： A61N5/1031 ,  A61N5/1036 ,  G06F19/00 ,  G06F19/3481

摘要： A method of optimizing a radiotherapy treatment plan is disclosed, comprising the steps of
a. Obtaining a deliverable input treatment plan,
b. Optimizing the deliverable input treatment plan to obtain an optimized treatment plan, using an objective function and at least one constraint, wherein
i. the objective function is related to reducing the plan complexity in terms of minimizing the machine output (MU) and/or minimizing the time required to deliver the plan and/or maximizing the segment area, and/or minimizing jaggedness of the MLC shapes,
ii. To ensure that the quality is maintained, the at least one constraint is based on the dose distribution of the input plan, related to maintaining an acceptable dose distribution.

摘要翻译： 优化放射疗法治疗计划的方法是游离缺失盘，其包括以下步骤：a。 获得输入递送治疗计划，B。 优化递送输入治疗计划，以获得优化的治疗计划，使用至少一个目标函数和约束在，worin我。 目标函数是关系到降低计划的复杂性最小化机输出（MU）的术语和/或最小化递送规划和/或最大化片段区域所需的时间，和/或最小化MLC形状的锯齿，二 ， 为了确保没有质量被保持，所述至少一个约束是基于所述输入计划，涉及到在可接受的剂量分布维持的剂量分布。

公开(公告)号：EP1297863A3

公开(公告)日：2004-01-07

申请号：EP02256657.4

申请日：2002-09-25

申请人： Siemens Medical Solutions USA, Inc.

发明人： Siochi, Ramon Alfredo Carvalho

IPC分类号： A61N5/10

CPC分类号： A61N5/1031 ,  A61N5/1036 ,  A61N5/1042

摘要： A system and method for controlling radiation delivery from a radiation source (20) to an object are disclosed. The method includes defining a field on the object for radiation delivery. The field includes a plurality of cells (102), each cell having a defined treatment intensity level. The cells are grouped to form a matrix (100) having at least one dimension approximately equal to a width of a collimator leaf (97, 98) capable of blocking radiation emitted from the radiation source. The method further includes decomposing the matrix into orthogonal matrices and optimizing delivery of the radiation by selecting a combination of orthogonal matrices to minimize junction effects.

公开(公告)号：EP1297863A2

公开(公告)日：2003-04-02

申请号：EP02256657.4

申请日：2002-09-25

申请人： Siemens Medical Solutions USA, Inc.

发明人： Siochi, Ramon Alfredo Carvalho

IPC分类号： A61N5/10

CPC分类号： A61N5/1031 ,  A61N5/1036 ,  A61N5/1042

摘要： A system and method for controlling radiation delivery from a radiation source (20) to an object are disclosed. The method includes defining a field on the object for radiation delivery. The field includes a plurality of cells (102), each cell having a defined treatment intensity level. The cells are grouped to form a matrix (100) having at least one dimension approximately equal to a width of a collimator leaf (97, 98) capable of blocking radiation emitted from the radiation source. The method further includes decomposing the matrix into orthogonal matrices and optimizing delivery of the radiation by selecting a combination of orthogonal matrices to minimize junction effects.

摘要翻译： 一种用于控制从辐射源（20）辐射递送至到对象的系统和方法游离缺失光盘。 该方法包括一个字段定义为辐射递送的对象。 该字段包括细胞的多个（102），每个单元具有所定义的治疗强度水平。 该单元被分组，以形成具有至少一个尺寸大约等于准直器叶片（97，98）能够阻断从所述辐射源发射的辐射的宽度的矩阵（100）。 该方法包括进一步的分解矩阵为正交矩阵，并且通过选择正交矩阵的组合，以尽量减少结效果优化辐射的递送。

公开(公告)号：EP3300769A2

公开(公告)日：2018-04-04

申请号：EP17197703.6

申请日：2015-09-09

申请人： Koninklijke Philips N.V.

发明人： VIK, Torbjoern ,  HEESE, Harald Sepp ,  BYSTROV, Daniel ,  WEESE, Rolf Jürgen ,  NEUKIRCHEN, Christoph ,  ISOLA, Alfonso Agatino ,  BAL, Matthieu Frédéric

IPC分类号： A61N5/10

CPC分类号： A61N5/1036 ,  A61N5/103 ,  A61N5/1031 ,  A61N5/1039 ,  A61N5/1045 ,  G06F19/3456 ,  G16H50/30

摘要： A radiation planning system includes a predictor-corrector optimizer unit which computes a predicted dose based on a collection of control points with a current approximate dose, each control point with a corresponding set of leaf positions, and determines an additional control point with a corresponding set of leaf positions based on a difference of the predicted fluence and the current approximate fluence through a least cost or shortest path in a layered graph structure of realizable leaf positions. Tools are described to help a planner to evaluate the effect of parameter changes to the current plan based on an identified zone of influence. The planner interactively views the current plan based on a visualization of the plan objectives and correlations between the objectives.

公开(公告)号：EP3266501A1

公开(公告)日：2018-01-10

申请号：EP17179966.1

申请日：2017-07-06

申请人： Shenyang Neusoft Medical Systems Co., Ltd.

发明人： XU, Xinghu ,  CHAI, Meng

IPC分类号： A61N5/10 ,  G21K1/04

CPC分类号： G21K1/046 ,  A61N5/1036 ,  A61N5/1045 ,  A61N5/1065

摘要： Methods and devices for controlling movement of a carriage of a multi-leaf collimator are provided. In one aspect, a method includes obtaining a desired position of each of a set of leaves on the carriage in each of a plurality of segments from a field, determining an allowable moving range set of the carriage according to the desired position, the allowable moving range set including a respective allowable moving range of the carriage in each of the segments, determining a respective position of the carriage in each of the segments according to the allowable moving range set, and controlling the movement of the carriage according to the determined positions of the carriage in the segments.

摘要翻译： 提供了用于控制多叶式准直器的滑架的移动的方法和装置。 在一个方面，一种方法包括：从场地获得多个片段中的每个片段中的滑架上的一组叶片中的每一个的期望位置;根据期望位置确定滑架的容许移动范围集合;允许移动 包括在每个区段中的滑架的相应允许移动范围;根据设定的允许移动范围确定滑架在每个区段中的相应位置;以及根据确定的位置，控制滑架的移动 段中的运输。

公开(公告)号：EP3003483B1

公开(公告)日：2017-12-27

申请号：EP14725093.0

申请日：2014-05-14

申请人： Koninklijke Philips N.V. ,  Philips GmbH

发明人： ISOLA, Alfonso Agatino ,  NEUKIRCHEN, Christoph ,  WEESE, Juergen ,  BAL, Matthieu Frédéric

IPC分类号： A61N5/10

CPC分类号： A61N5/1036 ,  A61N5/1045 ,  A61N5/1047 ,  A61N2005/1074

公开(公告)号：EP2782642B1

公开(公告)日：2016-03-16

申请号：EP11787690.4

申请日：2011-11-23

申请人： Brainlab AG

发明人： VILSMEIER, Stefan

IPC分类号： A61N5/10

CPC分类号： A61N5/103 ,  A61N5/1036 ,  A61N5/1045 ,  A61N5/1077 ,  A61N2005/1087 ,  G06F19/3481 ,  G21K5/00 ,  G21K5/04

公开(公告)号：EP2968979A2

公开(公告)日：2016-01-20

申请号：EP14723530.3

申请日：2014-03-11

申请人： Viewray Incorporated

发明人： DEMPSEY, James, F. ,  KAWRYKOW, Iwan

IPC分类号： A61N5/10

CPC分类号： A61N5/1031 ,  A61N5/1036 ,  A61N5/1045 ,  A61N5/1071 ,  A61N5/1077

摘要： The subject matter described herein provides methods for developing an IMRT treatment plan for a radiotherapy system. In one aspect, the method can include providing initial treatment parameters. These parameters can include a number of isotopic beams, a transmission angle for each beam, a prescribed dose for a target, and dose volume histogram constraints. The method can further include determining an initial fluence map including one or more beamlets. The initial fluence map can specify a fluence value for each beamlet. The method can further include determining a delivery sequence for the fluence values in the initial fluence map. The delivery sequence can include one or more apertures formed by the leaves of a collimator. These apertures can have a specified size constrained to substantially less than a maximum size associated with the collimator when the isotopic beam is near a critical structure. Related apparatus and systems are also described.

公开(公告)号：EP1352401A2

公开(公告)日：2003-10-15

申请号：EP01986871.0

申请日：2001-12-13

申请人： Elekta AB (publ)

发明人： ALBER, Markus

IPC分类号： G21K1/04

CPC分类号： A61N5/1031 ,  A61N5/1036 ,  G21K1/025

摘要： An optimisation method for a fluence pattern to be provided via a radiotherapeutic apparatus comprising a multi-leaf collimator comprises an iteration of a progressive solution (such as a gradient approach) of the fluence profile, at least some iterations including a weighted penalty function which varies between solutions favoured by the collimator design and solutions not so favoured, later iterations including the penalty function at a greater weight. Thus, the penalty function represents locally preferred solutions derived from the constraints of the multi-leaf collimator (MLC). As the iteration progresses, the greater weight assigned to the penalty function drives the method towards a solution which is possible given the MLC constraints. However, the lesser weight attached in the early stages of the iteration allows the method to settle towards a genuinely preferred solution. Overall, therefore, the method migrates towards a theoretically ideal solution and then diverts to a nearby practically possible solution. In this way, a solution is obtained which can be put into practice but is close to a theoretically ideal solution, i.e. a solution that would be preferred in the absence of MLC constraints.

公开(公告)号：EP0904805A2

公开(公告)日：1999-03-31

申请号：EP98307811.4

申请日：1998-09-25

申请人： SIEMENS MEDICAL SYSTEMS, INC.

发明人： Siochi, Ramon Alfredo

IPC分类号： A61N5/10

CPC分类号： A61N5/1042 ,  A61N5/1036

摘要： A system and method for radiation therapy delivery. The present invention provides for optimizing radiation delivery by accounting for the physical attributes of a beam shielding device (401) when determining an optimal radiation treatment These include, for example, constraining the optimization engine with realizable positioning of plates and/or collimator leaves. Thus, an optimal set of fields and intensity levels for those fields are chosen.

摘要翻译： 一种用于放射治疗输送的系统和方法。 本发明提供了在确定最佳辐射处理时考虑到束屏蔽装置（401）的物理属性来优化辐射传递。这些包括例如限制优化引擎与板和/或准直器叶的可实现的定位。 因此，选择这些领域的最佳的一组场和强度水平。