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    ROBUSTNESS EVALUATION OF BRACHYTHERAPY TREATMENT PLAN
    8.
    发明公开
    ROBUSTNESS EVALUATION OF BRACHYTHERAPY TREATMENT PLAN 审中-公开

    公开(公告)号：EP3466487A1

    公开(公告)日：2019-04-10

    申请号：EP17194553.8

    申请日：2017-10-03

    申请人： Koninklijke Philips N.V.

    发明人： ISOLA, Alfonso Agatino ,  NEUKIRCHEN, Christoph ,  HAUTVAST, Guillaume Leopold Theodorus Frederik ,  SENDEN, Dave

    IPC分类号： A61N5/10

    摘要： The invention relates to a system and a method for assisting in planning a radiation therapy treatment, the treatment being delivered on the basis of a treatment plan including error-prone parameter values of first treatment parameters. In the system, a robustness evaluation unit (10) obtains planned parameter values of the first treatment parameters, generates perturbed parameter configurations including perturbed values of the first treatment parameters, the perturbed parameter values deviating from the planned parameter values by possible error values of the first treatment parameters occurring during the treatment, and estimates for each perturbed parameter configuration a radiation dose distribution resulting from a treatment delivered on the basis of the perturbed parameter configuration and/or determines the treatment plan on the basis of the perturbed parameter configurations.

    WARM START INITIALIZATION FOR EXTERNAL BEAM RADIOTHERAPY PLAN OPTIMIZATION
    9.
    发明公开
    WARM START INITIALIZATION FOR EXTERNAL BEAM RADIOTHERAPY PLAN OPTIMIZATION 审中-公开

    公开(公告)号：EP3357539A1

    公开(公告)日：2018-08-08

    申请号：EP17154324.2

    申请日：2017-02-02

    申请人： Koninklijke Philips N.V.

    发明人： ISOLA, Alfonso Agatino ,  NEUKIRCHEN, Christoph ,  VIK, Orbjoern ,  HEESE, Harald Sepp ,  WEESE, Juergen

    IPC分类号： A61N5/10

    CPC分类号： A61N5/1031 ,  A61N5/1036 ,  A61N5/1047

    摘要： The invention relates to a dynamic sliding-window-like initialization for, for example, iterative VMAT algorithms. Specifically, a dynamic sliding window conversion method is contemplated where typical dynamic VMAT constraints are taken into account to find an optimal set of suitable openings (i.e. binary masks) that can be used as quasi-feasible start initialization for any VMAT algorithm that can refine until a deliverable plan is reached. Here, a multileaf leaf tip trajectory least square constrained optimization is performed to find a set of optimal unidirectional trajectories for all MLC leaf pairs of all arc points. To ensure that a quasi-feasible (or better quasi-deliverable) solution is returned, for example, a maximum dose rate, a maximum gantry speed, a maximum leafs speed, and a maximum treatment time may be enforced.

    RADIATION THERAPY PLANNING OPTIMIZATION AND VISUALIZATION
    10.
    发明公开
    RADIATION THERAPY PLANNING OPTIMIZATION AND VISUALIZATION 有权
    辐射治疗计划的优化和可视化

    公开(公告)号：EP3197553A2

    公开(公告)日：2017-08-02

    申请号：EP15774984.7

    申请日：2015-09-09

    申请人： Koninklijke Philips N.V.

    发明人： VIK, Torbjoern ,  HEESE, Harald Sepp ,  BYSTROV, Daniel ,  WEESE, Juergen ,  NEUKIRCHEN, Christoph ,  ISOLA, Alfonso Agatino ,  BAL, Matthieu Frederic

    IPC分类号： A61N5/10

    CPC分类号： A61N5/1036 ,  A61N5/103 ,  A61N5/1031 ,  A61N5/1039 ,  A61N5/1045 ,  G06F19/3456 ,  G16H50/30

    摘要： A radiation planning system includes a predictor-corrector optimizer unit which computes a predicted dose based on a collection of control points with a current approximate dose, each control point with a corresponding set of leaf positions, and determines an additional control point with a corresponding set of leaf positions based on a difference of the predicted fluence and the current approximate fluence through a least cost or shortest path in a layered graph structure of realizable leaf positions. Tools are described to help a planner to evaluate the effect of parameter changes to the current plan based on an identified zone of influence. The planner interactively views the current plan based on a visualization of the plan objectives and correlations between the objectives.

    摘要翻译： 辐射计划系统包括预测 - 校正器优化器单元，其基于具有当前近似剂量的控制点的集合来计算预测剂量，每个控制点具有对应的一组叶片位置，并且确定具有对应组的附加控制点 基于预测能量密度和当前近似注量之间的差异，通过可实现叶位置的分层图结构中的最小代价或最短路径。 描述的工具可帮助规划人员根据确定的影响区域评估参数更改对当前规划的影响。 规划人员根据计划目标的可视化和目标之间的相互关系，交互式地查看当前计划。