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公开(公告)号:EP4396198A2
公开(公告)日:2024-07-10
申请号:EP22772886.2
申请日:2022-08-31
发明人: DE LA ROSA, Kathrin , LEBEDIN, Mikhail , RATSWOHL, Christoph , VAZQUEZ GARCIA, Clara , SILVIS, Casper , EYER, Klaus , SIGVALDADÓTTIR, Ingibjörg , OLSSON, Simon
IPC分类号: C07K14/005 , A61K39/12 , G16B5/00
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公开(公告)号:EP4392461A1
公开(公告)日:2024-07-03
申请号:EP22860466.6
申请日:2022-08-23
发明人: YAN, Jiangyu , CAO, Rongbo , XIAO, Lin , ZENG, Junnan , HUANG, Limei , WEI, Xiling , LI, Zhaofeng , GONG, Qingwei , YAN, Xingguo , LI, Jing , HUANG, Danxia , CHEN, Xiaofeng , LI, Wenjia
CPC分类号: A61K38/18 , A61P3/00 , C07K14/475 , C07K16/46 , A61P3/08 , A61P3/06 , A61P3/04 , C07K2319/3020130101 , C07K2317/5220130101 , C07K2317/9420130101
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公开(公告)号:EP4387647A2
公开(公告)日:2024-06-26
申请号:EP22858988.3
申请日:2022-08-15
发明人: KUMAR, Ravindra
CPC分类号: A61K38/1796 , A61K38/05 , A61K38/556 , A61K38/13 , A61K38/2006 , A61K38/1774 , A61K38/1793 , A61K38/08 , A61K35/28 , C07K2319/3020130101 , A61K31/4178 , A61K31/55
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公开(公告)号:EP4386387A2
公开(公告)日:2024-06-19
申请号:EP24161302.5
申请日:2019-02-15
IPC分类号: G01N33/86
CPC分类号: C07K14/705 , C07K14/745 , G01N33/86 , C07K2319/0020130101 , G01N2333/75520130101 , C07K2319/3020130101
摘要: Various aspects of the invention relate to recombinant polypeptides that specifically bind human von Willebrand Factor. Such recombinant polypeptides typically include a modified extracellular domain of platelet glycoprotein Ibα that typically comprises at least one mutation selected from G233T, D235V, and K237V, and such recombinant polypeptides optionally include an oligomerization domain.
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公开(公告)号:EP4380961A1
公开(公告)日:2024-06-12
申请号:EP22854057.1
申请日:2022-08-02
IPC分类号: C07K14/475 , C07K16/28 , C07K14/50
CPC分类号: C07K14/475 , C07K14/50 , C07K2319/3020130101 , C07K14/4753 , C07K14/52
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16.
公开(公告)号:EP4380596A1
公开(公告)日:2024-06-12
申请号:EP22761883.2
申请日:2022-08-03
申请人: GENENTECH, INC. , Xencor, Inc.
IPC分类号: A61K38/17 , A61K38/20 , A61P35/00 , C07K14/54 , C07K14/715
CPC分类号: A61K38/1793 , A61K38/2086 , A61P35/00 , C07K14/5443 , C07K14/7155 , C07K2319/3020130101
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公开(公告)号:EP3490582B1
公开(公告)日:2024-06-12
申请号:EP17835212.6
申请日:2017-07-26
CPC分类号: C07K2319/3020130101 , A61P7/06 , A61P7/00 , C07K14/71 , A61K38/1796 , A61K45/06 , A61K31/519
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18.
公开(公告)号:EP4376870A1
公开(公告)日:2024-06-05
申请号:EP22850487.4
申请日:2022-07-27
发明人: YE, Fan , HUANG, Jianing , ZHONG, Ziyang
CPC分类号: C07K14/55 , C07K16/2818 , C07K2319/0020130101 , A61P35/00 , C07K2317/7620130101 , C07K2319/3020130101 , C07K14/5443
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公开(公告)号:EP4373861A2
公开(公告)日:2024-05-29
申请号:EP22846846.8
申请日:2022-07-22
CPC分类号: A61K47/68 , C07K2319/3020130101 , A61K38/00 , C07K14/62 , A61K45/06
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公开(公告)号:EP4373513A1
公开(公告)日:2024-05-29
申请号:EP22751630.9
申请日:2022-07-20
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