DRUG-COATED BALLOON CATHETERS FOR BODY LUMENS

    公开(公告)号:EP4275709A3

    公开(公告)日:2024-01-17

    申请号:EP23165652.1

    申请日:2018-05-04

    申请人: Urotronic, Inc.

    IPC分类号: A61L29/16

    摘要: Various embodiments disclosed relate to drug-coated balloon catheters for treating strictures in body lumens and methods of using the same. A drug-coated balloon catheter for delivering a therapeutic agent to a target site of a body lumen stricture includes an elongated balloon having a main diameter. The balloon catheter includes a coating layer overlying an exterior surface of the balloon. The coating layer includes one or more water-soluble additives and an initial drug load of a therapeutic agent.

    DRUG-LOADED MEDICAL INSTRUMENT AND PREPARATION METHOD THEREFOR

    公开(公告)号:EP4295891A1

    公开(公告)日:2023-12-27

    申请号:EP22755493.8

    申请日:2022-01-24

    摘要: The present application relates to the field of pharmaceutical technology, in particular, to a drug-loaded medical device, including a medical device body and at least one drug coating, the drug coating is attached to at least one side of a surface of the medical device body. The main component of the drug coating includes a macrolide drug. The drug coating includes elongated prismatic crystals each with at least three lateral edges, and/or the drug coating includes crystal clusters of the elongated prismatic crystals each with at least three lateral edges. An aspect ratio of each elongated prismatic crystal is in a range from 1: 1 to 40: 1. The drug-loaded medical device can effectively improve the drug transfer to the blood vessel wall and prolong the concentration of drug in tissue.