MULTI-GATE MULTI-FREQUENCY FILTER FOR ION MOBILITY ISOLATION

    公开(公告)号:EP3879262A1

    公开(公告)日:2021-09-15

    申请号:EP21161725.3

    申请日:2021-03-10

    IPC分类号: G01N27/622 H01J49/00

    摘要: An ion mobility separation apparatus comprises: a compartment having a gas therein; an electrode structure comprising a first plurality of electrodes within the compartment, the electrode structure defining a longitudinal axis; one or more power supplies electrically coupled to the electrodes, wherein the plurality of electrodes and the power supply are configured to maintain an electrical pseudopotential well encompassing and disposed parallel to the longitudinal axis and to maintain an electric field directed parallel to the longitudinal axis; an entrance ion gate disposed at a first end of the longitudinal axis; an exit ion gate disposed at a second end of the longitudinal axis; and at least one additional ion gate disposed between the entrance and exit ion gates.

    ACQUISITION OF FRAGMENT ION MASS SPECTRA OF IONS SEPARATED BY THEIR MOBILITY

    公开(公告)号:EP3786629A1

    公开(公告)日:2021-03-03

    申请号:EP20184939.5

    申请日:2016-10-20

    摘要: A method for acquiring fragment ion spectra of substances in complex substance mixtures wherein in a first measurement cycle a map of ion species with ion mobility scan times versus ion masses is measured, from which several sets of temporally separated ion species with distinct masses and distinct mobility scan times can be selected, preferably by using a trapping ion mobility spectrometer (TIMS), and wherein in further measurement cycles the ion species of a set each are selected by their mobility scan time, filtered by mass in the mass filter, and fragmented in the fragmentation cell, and wherein the fragment ion mass spectra are measured by the mass analyzer, and is characterized by the fact that two or more fragment ion mass spectra are measured for at least one ion species in different measurement cycles to improve the quality of the fragment ion mass spectra or a sum spectrum thereof or to verify a subsequently acquired fragment ion mass spectrum.