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11.发明公开Verfahren zur Herstellung einer mit B Vitaminen angereicherten Pflanze 有权维他命Zur Herstellung einer mit B Vitaminen angereicherten Pflanze
公开(公告)号：EP1867728A1
公开(公告)日：2007-12-19
申请号：EP07450110.7
申请日：2007-06-15
申请人： JHS-Privatstiftung
发明人： Fuchs, Norbert , Loidl, Rupert , Sadeghi, Behzad
CPC分类号： C12P25/00 , C12P13/02 , C12P17/12 , C12P17/167 , C12P17/182 , C12P17/186 , C12P19/42
摘要： Die vorliegende Erfindung betrifft ein Verfahren zur Produktion von organisch gebundenem Vitamin B, vorzugsweise Vitamin B1, B2, B3, B5, B6, B7, B9, B12 oder Mischungen hievon in Pflanzen,
wobei Pflanzensamen in einer Lösung des jeweiligen Vitamins getränkt und durch anschließendes Besprühen zu Vitamin B-angereicherten Pflanzenkeimlingen kultiviert werden.摘要翻译： 在植物中制备有机结合的维生素B，优选维生素B1，B2，B3，B5，B6，B7，B9和/或B12，包括将可发芽植物种子浸泡在各自的维生素或其混合物的溶液中，然后喷雾 在发芽过程中各自的维生素溶液。
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12.发明公开
公开(公告)号：EP1543026A1
公开(公告)日：2005-06-22
申请号：EP03750606.0
申请日：2003-09-23
申请人： DSM IP Assets B.V.
摘要： The present invention relates to a transcriptional activator gene for genes involved in cobalamin biosynthesis. More precisely, it relates to a process for amplifying the production of cobalamins and, more specifically, of coenzyme B12 by means of recombinant DNA techniques.
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公开(公告)号：EP1432809A2
公开(公告)日：2004-06-30
申请号：EP02796246.3
申请日：2002-08-20
CPC分类号： C12N9/1007 , C12P19/42
摘要： The invention relates to a method for producing vitamin B12 using Bacillus megaterium.
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14.发明公开Microbial production of vitamin B12 and production and use of compositions comprising high concentrations of vitamin B12 activity 失效微生物生产的维生素B12和生产和使用含高浓度维生素B12的组合物的
公开(公告)号：EP0824152A2
公开(公告)日：1998-02-18
申请号：EP97202466.5
申请日：1997-08-12
申请人： GIST-BROCADES B.V.
发明人： Bijl, Hendrik Louis
IPC分类号： C12P19/42
CPC分类号： C12P19/42 , A23K20/174 , A23L33/15 , A23V2002/00 , A61K8/673 , A61K8/99 , A61Q19/00 , Y10S435/822 , A23V2250/706 , A23V2250/206
摘要： The present invention provides a process for the preparation of natural vitamin B12, wherein said process comprises the steps of:
a) culturius microbial cells so that they produce, intracellularly, natural vitamin B12,
b) causing opening of the microbial cells such that vitamin B12 is released.
The present invention concerns also a composition comprising natural vitamin B12 in an amount greater than 0,1% weight based on the dry matter content of the composition.摘要翻译： 本发明提供了一种用于制备天然维生素B12的，worin所述方法包括以下步骤：a）culturius微生物细胞所以thatthey可以产生，细胞内，天然维生素B12，检查微生物细胞的b）致使开口做维生素B12 被释放。 因此，本发明涉及包含在量比基于组合物的干物质含量为0.1％重量更大的天然维生素B12的组合物。
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公开(公告)号：EP3292209A1
公开(公告)日：2018-03-14
申请号：EP16789409.6
申请日：2016-05-02
申请人： Hinoman Ltd
发明人： GLUKHMAN, Vladimir , ELITUV, Ehud
摘要： The present invention is directed to a system and method for producing vitamin B12 enriched Duckweed Bacterial Culture (DBC) composition. The aforementioned method comprises steps of inoculating at least one Lemnoideae species and at least one vitamin B12 producing bacteria species in a volume of growth media; incubating said at least one Lemnoideae species and said at least one vitamin B12 producing bacteria species under predetermined conditions to provide a Duckweed-Bacterial Culture (DBC); determining time intervals within said plots characterized by DBC with highest vitamin B12 content; and harvesting said DBC at said predetermined time intervals, thereby providing vitamin B12 enriched DBC composition. The present invention further discloses a composition comprising a vitamin B12 enriched Duckweed-Bacterial Culture (DBC), wherein said composition comprises at least one Lemnoideae species and at least one B12 producing bacteria species, further wherein said vitamin B12 content in said composition is in the range of between about 0.01 and about 100 μg per 100 g of said DBC.
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16.发明授权
公开(公告)号：EP2995204B9
公开(公告)日：2017-07-19
申请号：EP15176511.2
申请日：2015-07-13
IPC分类号： A23K20/174 , A23L33/15 , C12P19/42
CPC分类号： C12P19/42 , A23K20/174 , A23L33/15
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17.发明授权
公开(公告)号：EP2995204B1
公开(公告)日：2016-12-28
申请号：EP15176511.2
申请日：2015-07-13
IPC分类号： A23K20/174 , A23L33/15 , C12P19/42
CPC分类号： C12P19/42 , A23K20/174 , A23L33/15
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公开(公告)号：EP2580316A2
公开(公告)日：2013-04-17
申请号：EP11781589.4
申请日：2011-06-10
申请人： Probiotical S.p.A.
CPC分类号： C12N1/20 , A23L33/135 , A61K35/747 , C12P19/42 , C12R1/225
摘要： The present invention relates to a composition comprising at least one probiotic bacterial strain belonging to the species Lactobacillus reuteri as a vitamin B12 producer. In particular, the present invention relates to selected bacterial strains belonging to the species Lactobacillus reuteri as vitamin B12 producers. Finally, the present invention relates to a food composition or supplement or pharmaceutical composition comprising a bacterial strain belonging to the species Lactobacillus reuteri.
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19.发明授权DNA ENCODING FLAVIN-ADENINE-DINUCLEOTIDE-DEPENDENT-D-ERYTHRONATE-4-PHOSPHATE-DEHYDROGENASE , PDXR , AND MICROBIAL PRODUCTION OF VITAMIN B6 有权DNA编码黄素腺嘌呤二核苷酸ABHÄNGIGE-D-ERYTHRONAT -4-磷酸脱氢酶，PDXR，和维生素B6的微生物生产
公开(公告)号：EP1543124B1
公开(公告)日：2009-09-16
申请号：EP03750631.8
申请日：2003-09-25
申请人： DSM IP Assets B.V.
发明人： HOSHINO, Tatsuo , ICHIKAWA, Keiko , TAZOE, Masaaki
CPC分类号： C12N9/0006
摘要： The present invention relates to a DNA encoding a novel flavin adenine dinucleotide (FAD)-dependent D-erythronate 4-phosphate (EN4P) dehydrogenase originated from Sinorhizobium meliloti, which is involved in vitamin B6 biosynthesis, and a recombinant microorganism transformed with a vector having the DNA. It also relates to a process for production of vitamin B6 by using the recombinant microorganism. 'Vitamin B6' as used in this invention includes pyridoxol (PN), pyridoxal and pyridoxamine. Vitamin B6 is a vitamin indispensable to human beings or other animals, and is used as a raw material of medicines or as feed additives.
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20.发明授权
公开(公告)号：EP1543026B1
公开(公告)日：2006-08-02
申请号：EP03750606.0
申请日：2003-09-23
申请人： DSM IP Assets B.V.
摘要： The present invention relates to a transcriptional activator gene for genes involved in cobalamin biosynthesis. More precisely, it relates to a process for amplifying the production of cobalamins and, more specifically, of coenzyme B12 by means of recombinant DNA techniques.
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