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公开(公告)号：EP2890359A1
公开(公告)日：2015-07-08
申请号：EP12883949.5
申请日：2012-08-30
申请人： Avon Products, Inc.
发明人： SANTHANAM, Uma , HONG, Qi , YIM, Sungham
CPC分类号： A61K8/676 , A61K8/67 , A61K8/735 , A61K8/97 , A61K8/99 , A61K9/0014 , A61K36/064 , A61K2800/522 , A61Q15/00 , A61Q17/04 , A61Q19/00 , A61Q19/02 , A61Q19/06 , A61Q19/08
摘要： The present invention relates generally to compositions for topical application to the skin which comprise at least one DICKKOPF-1 expression modulator and the use of such compositions to provide benefits to the skin, including but not limited to lightening or darkening skin; treating hyper or hypopigmented skin; increasing or decreasing skin thickness; reducing or increasing skin hirsuteness; and/or changing skin phenotype from non-palmoplantar to palmoplantar.
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22.发明公开
公开(公告)号：EP2790666A2
公开(公告)日：2014-10-22
申请号：EP12857747.5
申请日：2012-12-11
申请人： Avon Products, Inc.
发明人： CHEN, Ying , ZHENG, Qian , LYGA, John W. , SANTHANAM, Uma , WYBORSKI, Russell , THORN LEESON, Daniel , KHUSIAL, Permanan Raaj
CPC分类号： A61K8/44 , A61K8/445 , A61K8/49 , A61K8/4926 , A61K8/494 , A61K8/97 , A61K36/00 , A61Q19/00 , A61Q19/02 , A61Q19/06 , A61Q19/08 , C12Q1/68
摘要： Methods of using extracts of Maesa japonica to impart anti-aging benefits to skin and/or improve skin conditions resulting from aging or damaged skin.
摘要翻译： 提供了用于预防，改善或减少皮肤老化症状的方法，其使用刺激胸腺素β-4在皮肤中表达的活性剂，除类视黄醇外。 还提供了用于筛选刺激胸腺素β-4表达水平的物质的方法以及使用筛选方案鉴定的活性剂治疗皮肤的方法。
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公开(公告)号：EP2516429B1
公开(公告)日：2020-06-24
申请号：EP10843468.9
申请日：2010-12-13
申请人： Avon Products, Inc.
发明人： ZHENG, Qian , WYBORSKI, Russell , SANTHANAM, Uma , LYGA, John W. , PTCHELINTSEV, Dmitri S. , CHEN, Siming, W.
IPC分类号： C07D471/00 , C07D471/18 , A61K31/437 , A61K36/00 , A61K8/49 , A61K8/97 , A61Q19/08
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公开(公告)号：EP3236992A1
公开(公告)日：2017-11-01
申请号：EP15868680.8
申请日：2015-09-03
申请人： AVON PRODUCTS, INC.
CPC分类号： A61K8/64 , A61K8/36 , A61K8/365 , A61K8/49 , A61K38/04 , A61Q19/08 , C07K5/08 , C07K5/10 , C07K7/00
摘要： Embodiments of the invention are related generally to the methods of diminishing the signs of aging in and/or improving health of human integuments, such as skin, and compositions comprising peptides useful therefor. The compositions according to the invention may comprise one or more peptides or fragments or derivatives thereof derived from a growth factor, e.g., Growth Differentiation Factor 11 (GDF11), in a topically acceptable vehicle.
摘要翻译： 本发明的实施方案一般涉及减少人体皮肤老化迹象和/或改善人体皮肤健康的方法，以及包含对其有用的肽的组合物。 根据本发明的组合物可以包含衍生自生长因子例如生长分化因子11（GDF11）的一种或多种肽或其片段或衍生物在局部可接受的载体中。
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公开(公告)号：EP3236982A1
公开(公告)日：2017-11-01
申请号：EP14908646.4
申请日：2014-12-23
申请人： Avon Products, Inc.
IPC分类号： A61K38/00
摘要： Provided are methods of diminishing the signs of aging and/or improving the health of human integuments, such as skin, and compositions comprising peptides useful therefor. The compositions according to the invention comprise a peptide comprising the sequence QILSKLRL (SEQ ID NO: 1) or a derivative, or a 3-5 amino acid fragment thereof, in a topically acceptable vehicle.
摘要翻译： 提供了减少老化迹象和/或改善人类皮肤如皮肤健康的方法，以及包含对其有用的肽的组合物。 根据本发明的组合物包含在局部可接受的载体中的包含序列QILSKLRL（SEQ ID NO：1）或其衍生物或其3-5个氨基酸片段的肽。
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公开(公告)号：EP2790666B1
公开(公告)日：2017-06-28
申请号：EP12857747.5
申请日：2012-12-11
申请人： Avon Products, Inc.
发明人： CHEN, Ying , ZHENG, Qian , LYGA, John W. , SANTHANAM, Uma , WYBORSKI, Russell , THORN LEESON, Daniel , KHUSIAL, Permanan Raaj
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28.发明公开METHOD OF IMPROVING AGING APPEARANCE OF SKIN BY MODULATION OF WIPI-1 审中-公开方法提高PUBLICATION图像的皮肤上老化通过调制WIPI-1
公开(公告)号：EP2931383A1
公开(公告)日：2015-10-21
申请号：EP13862258.4
申请日：2013-10-16
申请人： Avon Products, Inc.
IPC分类号： A61Q19/08
CPC分类号： A61K8/97 , A61K8/49 , A61K8/671 , A61Q19/08 , C12Q1/6876 , C12Q1/6883 , C12Q2600/136 , C12Q2600/148 , C12Q2600/158 , C12Q2600/16
摘要： Methods of using WIPI-1 to impart anti-aging benefits to the skin and/or improve skin conditions resulting from reduced autophagy activity. The present invention relates generally to compositions for topical application to the skin which comprise at least one WIPI-1 agonist and the use of such compositions to provide benefits to the skin, in particular, improving autophagy activity within skin cells and in a further embodiment improving the condition and appearance of chronologically or photo aged skin.
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29.发明公开
公开(公告)号：EP2747573A1
公开(公告)日：2014-07-02
申请号：EP12825830.8
申请日：2012-07-02
申请人： Avon Products, Inc.
CPC分类号： A61K8/97 , A61K36/19 , A61K36/48 , A61Q19/08 , A61K2300/00
摘要： Methods and compositions for preventing, ameliorating, or reducing dermatological signs of aging are provided which employ a botanical extract of
Justicia ventricosa, Archidendron clypearia, Abrus fruticulosus , or combinations thereof and a cosmetically acceptable vehicle.-
30.发明公开USE OF ECLIPTA PROSTRATA AND OTHER PPAR-GAMMA INHIBITORS IN COSMETICS AND COMPOSITIONS THEREOF 审中-公开旱莲草和其他PPARγ抑制剂的应用在化妆品和组合物中使用
公开(公告)号：EP2579843A1
公开(公告)日：2013-04-17
申请号：EP11792877.0
申请日：2011-05-25
申请人： Avon Products, Inc.
摘要： The present invention describes compositions and methods for improving the appearance of skin, particularly, treating, ameliorating, preventing, delaying, and/or improving one or more signs of excess accumulation and/or production of subcutaneous fat, such as cellulite, and conditions related thereto, by topically applying compositions comprising
Eclipta prostrata extracts or other anti-lipid agents.
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