-
公开(公告)号：EP2970300B1
公开(公告)日：2018-05-16
申请号：EP14717345.4
申请日：2014-03-14
IPC分类号： C07D487/04 , A61K31/519 , A61P19/02 , A61P11/06
CPC分类号： C07D487/04
摘要： The present invention encompasses compounds of the formula (I) wherein the groups X and Cy are defined herein, which are suitable for the treatment of diseases related to BTK, process of making, pharmaceutical preparations which contain compounds and their methods of use.
-
22.发明授权
公开(公告)号：EP2970163B1
公开(公告)日：2018-02-28
申请号：EP14719465.8
申请日：2014-03-13
IPC分类号： C07D277/56 , C07D417/04 , C07D487/08 , C07D487/10 , A61K31/426 , A61K31/427 , A61P11/06 , A61P19/02 , A61P29/00 , A61P37/00
CPC分类号： C07D277/56 , C07D417/04 , C07D487/08 , C07D487/10
摘要： The present invention encompasses compounds of the formula (I) wherein the groups ring A and Cy are defined herein, which are suitable for the treatment of diseases related to BTK, process of making, pharmaceutical preparations which contain compounds and their methods of use.
-
公开(公告)号：EP2970163A1
公开(公告)日：2016-01-20
申请号：EP14719465.8
申请日：2014-03-13
IPC分类号： C07D277/56 , C07D417/04 , C07D487/08 , C07D487/10 , A61K31/426 , A61K31/427 , A61P11/06 , A61P19/02 , A61P29/00 , A61P37/00
CPC分类号： C07D277/56 , C07D417/04 , C07D487/08 , C07D487/10
摘要： The present invention encompasses compounds of the formula (I) wherein the groups ring A and Cy are defined herein, which are suitable for the treatment of diseases related to BTK, process of making, pharmaceutical preparations which contain compounds and their methods of use.
-
公开(公告)号：EP2606045B1
公开(公告)日：2016-01-06
申请号：EP11748842.9
申请日：2011-08-11
发明人： BARTOLOZZI, Alessandra , BOSANAC, Todd , CHEN, Zhidong , DE LOMBAERT, Stephane , HUBER, John, D. , LO, Ho Yin , LOKE, Pui Leng , LIU, Weimin , MORWICK, Tina Marie , OLAGUE, Alan , RIETHER, Doris , TYE, Heather , WU, Lifen , ZINDELL, Renee
IPC分类号： C07D413/10 , C07D413/14 , C07D417/12 , C07D417/14 , C07D471/04 , C07D487/04 , C07D498/04 , A61K31/437 , A61K31/4439 , A61K31/444 , A61K31/497 , A61K31/4985 , A61K31/506 , A61K31/5365 , A61K31/5377 , A61K31/541 , A61P9/00 , A61P9/10 , A61P29/00 , A61P37/08 , A61P11/00
CPC分类号： C07D413/14 , C07D413/10 , C07D417/14 , C07D471/04 , C07D498/04
-
公开(公告)号：EP2619197B1
公开(公告)日：2015-08-05
申请号：EP11761775.3
申请日：2011-09-20
发明人： BARTOLOZZI, Alessandra , BOSANAC, Todd , CHEN, Zhidong , DE LOMBAERT, Stéphane , DINES, Jonathon, Alan , HUBER, John, D. , LIU, Weimin , LOKE, Pui Leng , MORWICK, Tina, Marie , OLAGUE, Alan , RIETHER, Doris , TYE, Heather , WU, Lifen , ZINDELL, Renee, M.
IPC分类号： C07D413/14 , A61K31/497 , A61P11/00
CPC分类号： C07D413/14
-
公开(公告)号：EP2609092B1
公开(公告)日：2015-04-01
申请号：EP11749686.9
申请日：2011-08-23
发明人： BARTOLOZZI, Alessandra , BOSANAC, Todd , CHEN, Zhidong , DE LOMBAERT, Stephane , DINES, Jonathon Alan , HUBER, John, D. , LIU, Weimin , LO, Ho Yin , LOKE, Pui Leng , MORWICK, Tina Marie , NEMOTO, Peter Allen , OLAGUE, Alan , RIETHER, Doris , TYE, Heather , WU, Lifen , ZINDELL, Renee, M.
IPC分类号： C07D413/10 , C07D413/14 , C07D417/14 , A61K31/4245 , A61P9/00 , A61P29/00 , A61P35/00
CPC分类号： C07D413/14 , A61K31/4245 , C07D413/10 , C07D417/14
-
公开(公告)号：EP2619196A1
公开(公告)日：2013-07-31
申请号：EP11761774.6
申请日：2011-09-20
发明人： BARTOLOZZI, Alessandra , BOSANAC, Todd , CHEN, Zhidong , DE LOMBAERT, Stéphane , HUBER, John, D. , LIU, Weimin , LO, Ho Yin , LOKE, Pui Leng , RIETHER, Doris , TYE, Heather , WU, Lifen , ZINDELL, Renee, M.
IPC分类号： C07D413/14 , A61K31/4245 , A61P9/10
CPC分类号： C07D413/14
摘要： The present invention relates to compounds of formula (I) and pharmaceutically acceptable salts thereof, wherein R
1 -R
5 are as defined herein. The invention also relates to pharmaceutical compositions comprising these compounds, methods of using these compounds in the treatment of various diseases and disorders, processes for preparing these compounds and intermediates useful in these processes.摘要翻译： 本发明涉及式（I）的化合物及其药学上可接受的盐，其中R 1 -R 5如本文所定义。 本发明还涉及包含这些化合物的药物组合物，使用这些化合物治疗各种疾病和病症的方法，制备这些化合物的方法和用于这些方法的中间体。
-
-
-
-
-
-
搜索结果
27 条记录 (耗时 0.03 秒)
