公开(公告)号：EP1261736A2

公开(公告)日：2002-12-04

申请号：EP01906704.0

申请日：2001-01-25

申请人： HYSEQ, INC.

发明人： KUO, Chiauyun ,  HALEY, Dana, A. ,  BOYLE, Bryan, J. ,  ARTERBURN, Matthew, C. ,  TANG, Y., Tom ,  LIU, Chenghua ,  DRMANAC, Radoje, A.

IPC分类号： C12Q1/68 ,  C07K14/00 ,  C07H21/02

CPC分类号： C07K14/70503 ,  C07K14/475

摘要： The invention provides novel polynucleotides and polypeptides encoded by such polynucleotides and mutants or variants thereof that correspond to a novel human secreted Pref-1-like polypeptide. These polynucleotides comprise nucleic acid sequences isolated from cDNA library from adult human brain (Hyseq clone identification numbers 7958079 (SEQ ID NO:1)). Other aspects of the invention include vectors containing processes for producing novel human secreted Pref-1-like polypeptides, and antibodies specific for such polypeptides.

公开(公告)号：EP1254269A1

公开(公告)日：2002-11-06

申请号：EP01908837.6

申请日：2001-02-02

申请人： Hyseq Inc.

发明人： BOYLE, Bryan, J. ,  YEUNG, George ,  ARTERBURN, Matthew, C. ,  LIU, Chenghua ,  TANG, Y., Tom ,  GODBOLE, Shubhada, D. ,  KUO, Chiaoyun ,  DRMANAC, Radoje, T. ,  PALENCIA, Sereando

IPC分类号： C12Q1/68 ,  C12P19/34 ,  C07H21/04 ,  C07K5/00 ,  A61K39/395

CPC分类号： C12N9/6432 ,  A61K38/00 ,  C07K14/47 ,  C12N9/16 ,  C12Y304/21006

摘要： The invention provides novel polynucleotides and polypeptides encoded by such polynucleotides and mutants or variants thereof that correspond to novel human secreted NGM-like polypeptides. These polynucleotides comprise nucleic acid sequences isolated from at least cDNA libraries prepared from adult spleen mRNA (GIBCO) (Hyseq clone identification numbers 3073928 (SEQ ID NO: 1), and from infant brain mRNA (Columbia University) (Hyseq clone identification number 6346549) (SEQ ID NO: 18). Other aspects of the invention include vectors containing processes for producing novel human secreted NGM-like polypeptides, and antibodies specific for such polypeptides.

公开(公告)号：EP1254246A1

公开(公告)日：2002-11-06

申请号：EP01905050.9

申请日：2001-01-25

申请人： HYSEQ, INC.

发明人： BOYLE, Bryan, J. ,  MIZE, Nancy, K. ,  ARTERBURN, Matthew, C. ,  PALENCIA, Servando ,  TANG, Y., Tom ,  LIU, Chenghua ,  DRMANAC, Radoje, A. ,  LABAT, Ivan ,  STACHE-CRANE, Birgit ,  NGUYEN, Kody ,  GARCIA, Veronica E.

IPC分类号： C12P21/06

CPC分类号： C07K14/70503 ,  A61K38/00 ,  C07K14/495 ,  C07K14/715 ,  C07K16/00 ,  C12N9/16 ,  C12N9/6432 ,  C12Y304/21006

摘要： The invention provides novel polynucleotides and polypeptides encoded by such polynucleotides and mutants or variants thereof that correspond to a novel human secreted TGF alpha-like polypeptide. These polynucleotides comprise nucleic acid sequences isolated from cDNA library from human adult kidney (Hyseq clone identification number 16441036). Other aspects of the invention include vectors containing processes for producing novel human secreted TGF alpha-like polypeptides, and antibodies specific for such polypeptides.

公开(公告)号：EP1242596A1

公开(公告)日：2002-09-25

申请号：EP00986742.5

申请日：2000-12-22

申请人： HYSEQ, INC.

发明人： BOYLE, Bryan, J. ,  MIZE, Nancy, K. ,  ARTERBURN, Matthew, C. ,  TANG, Y., Tom ,  LIU, Chenghua ,  DRMANAC, Radoje, T.

IPC分类号： C12N15/12 ,  G01N33/53

摘要： The invention provides novel polynucleotides and polypeptides encoded by such polynucleotides and mutants or variants thereof that correspond to a novel human von Willebrand/Thrombospondin-like polypeptide. These polynucleotides comprise nucleic acid sequences isolated from cDNA library from human fetal brain (Hyseq clone identification number 15258924). Other aspects of the invention include vectors containing processes for producing novel human von Willebrand/Thrombospondin-like polypeptides, and antibodies specific for such polypeptides.

公开(公告)号：EP1242580A1

公开(公告)日：2002-09-25

申请号：EP00989452.8

申请日：2000-12-22

申请人： HYSEQ, INC.

发明人： BOYLE, Bryan, J. ,  YEUNG, George, Y. ,  ARTERBURN, Matthew, C. ,  MIZE, Nancy, K. ,  TANG, Y., Tom ,  LIU, Chenghua ,  DRMANAC, Radoje, T.

IPC分类号： C12N5/10 ,  C12N15/12 ,  C12N15/16 ,  C12N15/63 ,  C12N15/64 ,  C07K14/47 ,  C07K14/475 ,  C07K14/48 ,  C07K16/18 ,  C07K16/22 ,  A61K38/16 ,  A61K38/17 ,  A61K38/18 ,  A61K38/19

摘要： The invention provides novel polynucleotides and polypeptides encoded by such polynucleotides and mutants or variants thereof that correspond to a novel human secreted semaphorin-like polypeptide. These polynucleotides comprise nucleic acid sequences isolated from cDNA library from fetal liver-spleen (Hyseq clone identification numbers 5688868 (SEQ ID NO: 1)). Other aspects of the invention include vectors containing processes for producing novel human secreted semaphorin-like polypeptides, and antibodies specific for such polypeptides.

公开(公告)号：EP1240178A2

公开(公告)日：2002-09-18

申请号：EP00989432.0

申请日：2000-12-22

申请人： HYSEQ, INC.

发明人： HALEY, Dana, A. ,  BOYLE, Bryan, J. ,  SUK-YUE HO, Alice ,  ZHOU, Ping ,  MIZE, Nancy, K. ,  KUO, Chiauyun ,  ARTERBURN, Matthew, C. ,  TANG, Y., Tom ,  LIU, Chenghua ,  DRMANAC, Radoje

IPC分类号： C07H21/02 ,  C07H21/04 ,  C07K14/00 ,  C12N1/21 ,  C12N9/00 ,  C12N15/00 ,  C12N15/63 ,  C12N15/85 ,  C12N15/86

CPC分类号： C12N9/6432 ,  A61K38/00 ,  C07K14/70503 ,  C12N9/16 ,  C12Y304/21006

摘要： The invention provides novel polynucleotides and polypeptides encoded by such polynucleotides and mutants or variants thereof that correspond to a novel secreted prothrombinase-like polypeptide. These polynucleotides comprise nucleic acid sequences isolated from cDNA library from human ovary (Hyseq clone identification numbers 773565 (SEQ ID NO: 1) and 7727065 (SEQ ID NO: 11)). Other aspects of the invention include vectors containing processes for producing novel secreted prothrombinase-like polypeptides, and antibodies specific for such polypeptides.