公开(公告)号：EP1163366B1

公开(公告)日：2007-08-08

申请号：EP00907713.2

申请日：2000-02-24

申请人： SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (S.C.R.A.S.) ,  CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS)

发明人： CAMARA Y FERRER, José, Antonio ,  THURIEAU, Christophe ,  MARTINEZ, Jean ,  BERGE, Gilbert ,  GOZE, Catherine, Résidence Château d'Alco

IPC分类号： C12Q1/68 ,  G06F17/30

CPC分类号： C12N15/1089

摘要： The invention concerns a method for identifying peptides presumed to have a specific function selected among nucleotide or peptide sequences of unknown function, comprising steps which consist in: (i) providing a polynucleotide or polypeptide databank; (ii) screening said databank to search for the presence of a combination of nucleotides or amino acids signalling the peptide with specific function; (iii) identifying the polynucleotide or polypeptide sequences which comprise the combination of nucleotides or amino acids signalling the peptide with specific function.

公开(公告)号：EP1246837B1

公开(公告)日：2005-10-26

申请号：EP01903924.7

申请日：2001-01-11

申请人： CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS)

发明人： AMBLARD, Muriel ,  MARTINEZ, Jean ,  BERGE, Gilbert

IPC分类号： C07K7/02 ,  C07K14/575 ,  C08L77/10 ,  C08L77/02

CPC分类号： C07K7/02 ,  C07K14/57509

公开(公告)号：EP3527580A1

公开(公告)日：2019-08-21

申请号：EP18305160.6

申请日：2018-02-16

申请人： Centre National de la Recherche Scientifique CNRS ,  Universite De Montpellier (Universite Montpellier 2 Sciences Et Techniques) ,  Ecole Nationale Supérieure de Chimie de Montpellier ,  Ecole des Mines d'Ales ,  Association pour la Recherche et le Développement des Méthodes et Processus Industriels (ARMINES)

发明人： YEBOUE, Yves ,  GALLARD, Benjamin ,  LE MOIGNE, Nicolas ,  LAMATY, Frédéric ,  MARTINEZ, Jean ,  METRO, Thomas-Xavier

IPC分类号： C07K1/06 ,  B29C47/38

摘要： The present disclosure relates to A a continuous, solvent-free and non-enzymatic method for synthesizing a compound of formula (I) :

         Ra-POLYPEP-Rc     (I)

wherein :
POLYPEP is a poly-amino acid compound,
Ra and Rc are as specified in the disclosure,
which method comprises the steps of:
a) feeding an extrusion reactor with
(1) a compound of formula (II)

         Ra-PEPNt-Rg     (II)

wherein;
PEPNt is a mono- or a poly-aminoacid compound,
Ra and Rg are as specified in the disclosure,
and
(2) a compound of formula (III)

         H-PEPCt-Rc     (III)

wherein :
PEPCt is a mono- or a poly-amino acid compound, and
Rc is as defined in the disclosure
in the absence of any solvent,
so that the compound of formula (II) and the compound of formula (III) react together for generating a compound of formula (I), and

b) collecting the compound of formula (I) from the extrusion reactor.

公开(公告)号：EP3178867A1

公开(公告)日：2017-06-14

申请号：EP15306964.6

申请日：2015-12-09

申请人： UNIVERSITE DE MONTPELLIER ,  CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE -CNRS-

发明人： MARTINEZ, Jean ,  MEHDI, Ahmad ,  SUBRA, Gilles ,  JEBORS, Saïd

IPC分类号： C08G69/10

CPC分类号： C08G69/10

摘要： The present invention relates to new biopolymer, i.e. bioorganic nylons incorporating peptidic blocks obtained by a process of polymerization of amino peptidic blocks. The process of the invention comprises the steps of mixingamino peptidic blocks with or without a diaminoalcane and reacting the mixture according to polycondensation with a diacyl chloride in homogeneous or heterogeneous media.

摘要翻译： 本发明涉及新的生物聚合物，即结合通过氨基肽段聚合过程获得的肽片段的生物有机尼龙。 本发明的方法包括在有或没有二氨基癸烷的情况下混合氨基肽类嵌段并且使该混合物根据缩聚与二酰基氯在均相或非均相介质中反应的步骤。

公开(公告)号：EP1608674B1

公开(公告)日：2011-12-07

申请号：EP03816674.0

申请日：2003-04-02

申请人： De Sangosse SA ,  CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS)

发明人： BESNARD, Olivier ,  MARTINEZ, Jean ,  CAVELIER, Florine

IPC分类号： C07K7/06 ,  C07C237/22 ,  C07K5/062 ,  C07K5/083 ,  C07K5/103

CPC分类号： A01N37/46 ,  C07K5/06026 ,  C07K5/0806 ,  C07K5/1008 ,  C07K7/06

摘要： The invention relates to oligopeptides used as elicitors of the natural defences of plants in order to control fungal and/or bacterial and/or viral pathogens and/or crop pests, by means of foliar or root application or by injection. According to the invention, said oligopeptides are characterised in that they are obtained by organic or enzymatic synthesis, in that they are heteropolymers and/or homopolymers of protein and/or non-protein amino acids, and in that said amino acids form sequences of said polymers selected for the capacity thereof to form spiral structures.

公开(公告)号：EP1608674A1

公开(公告)日：2005-12-28

申请号：EP03816674.0

申请日：2003-04-02

申请人： De Sangosse SA ,  CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS)

发明人： BESNARD, Olivier ,  MARTINEZ, Jean ,  CAVELIER, Florine

IPC分类号： C07K7/06 ,  C07C237/22 ,  C07K5/062 ,  C07K5/083 ,  C07K5/103

CPC分类号： A01N37/46 ,  C07K5/06026 ,  C07K5/0806 ,  C07K5/1008 ,  C07K7/06

摘要： The invention relates to oligopeptides used as elicitors of the natural defences of plants in order to control fungal and/or bacterial and/or viral pathogens and/or crop pests, by means of foliar or root application or by injection. According to the invention, said oligopeptides are characterised in that they are obtained by organic or enzymatic synthesis, in that they are heteropolymers and/or homopolymers of protein and/or non-protein amino acids, and in that said amino acids form sequences of said polymers selected for the capacity thereof to form spiral structures.

公开(公告)号：EP1163366A1

公开(公告)日：2001-12-19

申请号：EP00907713.2

申请日：2000-02-24

申请人： SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (S.C.R.A.S.) ,  CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS)

发明人： CAMARA Y FERRER, José, Antonio ,  THURIEAU, Christophe ,  MARTINEZ, Jean ,  BERGE, Gilbert ,  GOZE, Catherine,Résidence Château d'Alco

IPC分类号： C12Q1/68 ,  G06F17/30

CPC分类号： C12N15/1089

摘要： The invention concerns a method for identifying peptides presumed to have a specific function selected among nucleotide or peptide sequences of unknown function, comprising steps which consist in: (i) providing a polynucleotide or polypeptide databank; (ii) screening said databank to search for the presence of a combination of nucleotides or amino acids signalling the peptide with specific function; (iii) identifying the polynucleotide or polypeptide sequences which comprise the combination of nucleotides or amino acids signalling the peptide with specific function.

公开(公告)号：EP2459229B1

公开(公告)日：2018-02-28

申请号：EP10745190.8

申请日：2010-08-02

申请人： Centre National de la Recherche Scientifique (C.N.R.S.) ,  Université de Montpellier I ,  Institut National de la Santé et de la Recherche Médicale

发明人： AMBLARD, Muriel ,  MARTINEZ, Jean ,  VEZENKOV, Lubomir ,  HERNANDEZ, Jean-François ,  GARCIA, Marcel ,  MAYNADIER, Marie

IPC分类号： A61K47/64

CPC分类号： A61K47/34 ,  A61K47/64 ,  A61K47/645

公开(公告)号：EP1753781B1

公开(公告)日：2012-09-26

申请号：EP05770968.5

申请日：2005-05-10

申请人： INSTITUT EUROPEEN DE BIOLOGIE CELLULAIRE ,  Centre National de la Recherche Scientifique ,  Université de Montpellier I ,  Université Montpellier II

发明人： HOCQUAUX, Michel ,  PINEL, Anne-Marie ,  MARTINEZ, Jean ,  SUBRA, Gilles

IPC分类号： C07K14/685 ,  C07K7/06 ,  C07K5/04 ,  A61K47/48

CPC分类号： A61K47/54

公开(公告)号：EP1753781A1

公开(公告)日：2007-02-21

申请号：EP05770968.5

申请日：2005-05-10

申请人： INSTITUT EUROPEEN DE BIOLOGIE CELLULAIRE ,  Centre National de la Recherche Scientifique ,  Université de Montpellier I ,  Université Montpellier II

发明人： HOCQUAUX, Michel ,  PINEL, Anne-Marie ,  MARTINEZ, Jean ,  SUBRA, Gilles

IPC分类号： C07K14/685 ,  C07K7/06 ,  C07K5/04 ,  A61K47/48

CPC分类号： A61K47/54

摘要： The invention relates to a peptide of formula W-DPhe-Arg- Z (I) and to a conjugate thereof of a formula A-W-DPhe-Arg-Z (II), wherein A is a radical corresponding to a monocarboxylic acid of general formula HOOC-R (III), wherein R is an linear or branched possibly substituted by a hydroxy group aliphatic C1-C24 radical which can comprise one or several unsaturations, preferably from 1 to 6 unsaturations, a lipoic acid or the reduced form thereof, a dihydrolipoic acid, N-lipoyl-lysine or a phenylbutyric acid, W is His, Ala-His, Ala-Ala-His, Nle-Ala-His, DTrp-Ala-His, Nle-Trp-His, Lys, Ala-Lys, Nle-Ala-Lys, Orn, Ala-Orn, Nle-Ala-Orn, Ala, Nle-Ala-Ala, Arg, Ala-Arg, Nle-Ala-Arg, Nle-Ala-DTrp or a bond in case of compounds of formula (II), Z is NH2, OH and OR, wherein R is a linear or branched aliphatic C1-C24 radical, TrpNH2, NapNH2, TpiNH2, TicNH2, AlaNH2i TrpOH, NapOH, TpiOH, TicOH, AlaOH, PheNH2, or PheOH, exempting a peptidic conjugate for which A is a radical corresponding to an acetic acid, W is Nle-Ala-His and Z is TrpNH2 in the form of enantiomers or diastereoisomer and the mixtures thereof including racemic mixtures. The use of the inventive compounds for cosmetically fighting against canities is also disclosed.