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    DISTILLATION APPARATUS
    21.
    发明公开
    DISTILLATION APPARATUS 有权
    蒸馏装置

    公开(公告)号：EP3213813A1

    公开(公告)日：2017-09-06

    申请号：EP15855758.7

    申请日：2015-11-02

    申请人： LG Chem, Ltd.

    发明人： LEE, Sung Kyu ,  SHIN, Joon Ho

    IPC分类号： B01J12/02 ,  C07C7/04 ,  C07C11/02 ,  C07C11/107 ,  C07B63/00

    CPC分类号： C07C7/04 ,  B01D3/007 ,  B01D3/143 ,  B01D3/32 ,  B01D3/42 ,  B01D3/4211 ,  C07C9/15 ,  C07C11/02 ,  C07C11/107

    摘要： The present application relates to a distillation device. The distillation device of the present application can minimize energy loss occurring in a purification process of the olefin monomer, the solvent, and the raw material including, for example, 1-octene, iso-octene, and n-hexane, used in a polymerization process of the polyolefin elastomer, and can increase economic efficiency by isolating a high-purity product.

    摘要翻译： 本申请涉及一种蒸馏装置。 本申请的蒸馏装置可以使烯烃单体，溶剂和包括例如聚合中使用的1-辛烯，异辛烯和正己烷的原料在纯化过程中发生的能量损失最小化 聚烯烃弹性体的工艺，并且可以通过分离高纯度产品来提高经济效率。

    SEMI-CONTINUOUS CRYSTALLIZATION METHOD AND APPARATUS
    25.
    发明公开
    SEMI-CONTINUOUS CRYSTALLIZATION METHOD AND APPARATUS 审中-公开
    半连续结晶方法和装置

    公开(公告)号：EP3108947A1

    公开(公告)日：2016-12-28

    申请号：EP15173637.8

    申请日：2015-06-24

    申请人： Sulzer Chemtech AG

    发明人： Pfeil, Mathias ,  Stepanski, Manfred

    IPC分类号： B01D9/00 ,  C07B63/00 ,  C07C7/14 ,  C07C51/43

    CPC分类号： C07B63/00 ,  B01D9/0013 ,  B01D9/004 ,  B01D2009/0086 ,  C07C7/14 ,  C07C51/43 ,  C07C15/08 ,  C07C15/02 ,  C07C59/08

    摘要： A process for the separation of a substance from a liquid feed mixture and for the purification of the substance by fractional layer crystallization, wherein the liquid feed mixture comprises the substance to be separated and purified in a concentration of less than 70 % by weight, which comprises the subsequent steps in the given order:
    (a) feeding the liquid feed mixture into a crystallization zone, in which at least one surface is provided, so that at least a part of the surface contacts the liquid feed mixture,
    (b) cooling the at least one surface of the crystallization zone to a temperature below the equilibrium freezing temperature of the liquid feed mixture so that a crystal layer enriched in the substance to be separated and purified is deposited on the at least one cooled surface, whereby a mother liquid having a lower concentration of the substance to be separated and purified than the liquid feed mixture is formed from the liquid feed mixture,
    (c) removing at least a portion of the mother liquid from the crystallization zone,
    (d) adding a further portion of liquid feed mixture into the crystallization zone,
    (e) allowing further deposition of a crystal layer enriched in the substance to be separated and purified to take place on the at least one cooled surface,
    (f) optionally carrying out a sweating stage and removing a sweating residue and
    (g) melting the crystal layer to obtain the separated and purified substance.

    摘要翻译： 一种从液体进料混合物中分离物质和通过分层结晶纯化物质的方法，其中液体进料混合物包含待分离和纯化的物质，其浓度小于70重量％，其中 包括以给定顺序的后续步骤：（a）将液体进料混合物进料到结晶区中，其中提供至少一个表面，使得至少一部分表面接触液体进料混合物，（b）冷却 将结晶区的至少一个表面冷却到低于液体进料混合物的平衡冷冻温度的温度，使得富集待分离和纯化的物质的晶体层沉积在至少一个冷却表面上，由此得到母液 （c）从所述液体进料混合物形成具有比所述液体进料混合物更低浓度的待分离和纯化的物质，（c）除去至少一部分 （d）将另一部分液体进料混合物加入到结晶区中，（e）允许进一步沉积富含待分离和纯化的物质的晶体层以在所述结晶区中发生 至少一个冷却表面，（f）任选地进行发汗阶段并除去发汗残余物，和（g）熔化结晶层以获得分离和纯化的物质。

    LYSOPHOSPHATIDIC ACID DETECTION
    29.
    发明公开
    LYSOPHOSPHATIDIC ACID DETECTION 有权
    LYSOPHOSPHATIDSÄURENACHWEIS

    公开(公告)号：EP2970325A4

    公开(公告)日：2016-08-31

    申请号：EP14765163

    申请日：2014-03-14

    申请人： UNIV PORTLAND STATE

    发明人： STRONGIN ROBERT ,  SIBRIAN-VAZQUEZ MARTHA ,  WANG JIALU ,  WANG LEI ,  ESCOBEDO CORDOVA JORGE O

    IPC分类号： C07D491/107 ,  C07B63/00 ,  C07D491/22 ,  C09K11/06 ,  G01N21/64 ,  G01N33/52 ,  G01N33/92

    CPC分类号： G01N33/92 ,  C07D491/107 ,  C07D491/22 ,  C09B11/24

    摘要： Embodiments of methods and compounds for isolating and detecting lysophosphatidic acids (LPAs) are disclosed. Kits for performing the methods also are disclosed. LPAs are isolated from biological samples by liquid-liquid extraction followed by solid phase extraction. LPA species may be separated by HPLC, and the separated species may be identified and quantified. Also disclosed are embodiments of compounds capable of universally detecting a plurality of LPA species with substantially equivalent sensitivity. Embodiments of the disclosed compounds are useful for determination of total LPA concentration in a sample comprising a plurality of LPA species without separation of individual LPA species.

    摘要翻译： 公开了用于分离和检测溶血磷脂酸（LPAs）的方法和化合物的实施方案。 用于执行方法的套件也被公开。 LPA通过液 - 液萃取分离生物样品，随后进行固相萃取。 可以通过HPLC分离LPA物质，并且可以鉴定和定量分离的物种。 还公开了能够普遍检测具有基本相当的灵敏度的多个LPA物质的化合物的实施方案。 所公开的化合物的实施方案可用于测定包含多种LPA物质的样品中的总LPA浓度，而不分离各个LPA物质。