专利检索 ap:"Senesco Technologies, Inc." 第 4 页

31.

发明公开
METHODS OF INCREASING SEED YIELD 审中-公开
标题翻译：方法以提高种子产量

公开(公告)号：EP1824982A2

公开(公告)日：2007-08-29

申请号：EP05852821.7

申请日：2005-12-05

申请人： Senesco Technologies, Inc.

发明人： THOMPSON, John, E. , NOWACK, Linda , WU, Wendy , WANG, Tzann-Wei

IPC分类号： C12N15/82

CPC分类号： C12N15/8261 , C07K14/415 , Y02A40/146

摘要： The present invention relates to unique isoforms of eukaryotic initiation Factor 5A ("eIF-5A"): senescence-induced eIF-5A; wounding/pathogen induced eIF-5A; stress eIF-5A and growth eIF-5A, as well as polynucleotides that encode these three factors. The present invention also relates to methods involving modulating the expression of these factors. The present invention also relates to deoxyhypusine synthase ("DHS"), polynucleotides that encode DHS, and methods involving modulating the expression of DHS.

32.

发明公开
USE OF APOPTOSIS-SPECIFIC EIF-5A SIRNAS AND ANTISENSE POLYNUCLEOTIDES TO INHIBIT/SUPPRESS AN INFLAMMATORY RESPONSE 审中-公开
标题翻译：凋亡特异性EIF-5A的siRNA和反义多核苷酸用于阻止/抑制炎症过程的

公开(公告)号：EP1769075A2

公开(公告)日：2007-04-04

申请号：EP05790728.9

申请日：2005-07-20

申请人： Senesco Technologies, Inc.

发明人： THOMPSON, John, E. , HOPKINS, Marianne , BOONE, Adrienne , REZNIKOV, Leonid , DINARELLO, Charles , TAYLOR, Catherine , GALTON, Bruce, C.

IPC分类号： C12N15/11

CPC分类号： C12N15/113 , C12N2310/111 , C12N2310/14 , C12N2310/53

摘要： The present invention relates to apoptosis specific eucaryotic initiation factor 5A (eIF-5A), referred to as apoptosis-specific eIF-5A or eIF5-A1, nucleic acids and polypeptides and methods for inhibiting or suppressing apoptosis in cells using antisense nucleotides or siRNAs to inhibit expression of apoptosis-specific eIF-5A. The invention also relates to suppressing or inhibiting expression of pro-inflammatory cytokines or inhibiting activation of NFkB by inhibiting expression of apoptosis-specific eIF-5A.

33.

发明公开
NUCLEIC ACIDS, POLYPEPTIDES, AND METHODS FOR MODULATING APOPTOSIS 有权
标题翻译： NUCLEIC，多肽和方法调制凋亡

公开(公告)号：EP1509251A2

公开(公告)日：2005-03-02

申请号：EP03728710.9

申请日：2003-05-07

申请人： Senesco Technologies, Inc.

发明人： TAYLOR, Catherine , WANG, Tzann-Wei , PETROV, Larry , CARLSON, John, C. , NARAYANSINGH, Richard , THOMPSON, John, E. , CLICHE, Dominic , KAUP, Marianne

IPC分类号： A61K48/00

CPC分类号： C12N15/1136 , C07K14/4747 , C12N9/0004 , C12N15/1137 , C12Q1/6876 , C12Q2600/158

摘要： The present invention relates to isolated and/or purified rat apoptosis-specific eucaryotic initiation Factor-5A (eIF-5A) and deoxyhypusine synthase (DHS) nucleic acids and polypeptides. The present invention also relates to methods of modulating apoptosis using apoptosis-specific eIF-5A and DHS, and antisense oligonucleotides and expression vectors of apoptosis-specific eIF-5A and DHS useful in such methods.