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公开(公告)号：EP1509251B1
公开(公告)日：2008-02-27
申请号：EP03728710.9
申请日：2003-05-07
发明人： TAYLOR, Catherine , WANG, Tzann-Wei , PETROV, Larry , CARLSON, John, C. , NARAYANSINGH, Richard , THOMPSON, John, E. , CLICHE, Dominic , KAUP, Marianne
CPC分类号： C12N15/1136 , C07K14/4747 , C12N9/0004 , C12N15/1137 , C12Q1/6876 , C12Q2600/158
摘要： The present invention relates to isolated and/or purified rat apoptosis-specific eucaryotic initiation Factor-5A (eIF-5A) and deoxyhypusine synthase (DHS) nucleic acids and polypeptides. The present invention also relates to methods of modulating apoptosis using apoptosis-specific eIF-5A and DHS, and antisense oligonucleotides and expression vectors of apoptosis-specific eIF-5A and DHS useful in such methods.
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公开(公告)号：EP1509251A2
公开(公告)日：2005-03-02
申请号：EP03728710.9
申请日：2003-05-07
发明人： TAYLOR, Catherine , WANG, Tzann-Wei , PETROV, Larry , CARLSON, John, C. , NARAYANSINGH, Richard , THOMPSON, John, E. , CLICHE, Dominic , KAUP, Marianne
IPC分类号： A61K48/00
CPC分类号： C12N15/1136 , C07K14/4747 , C12N9/0004 , C12N15/1137 , C12Q1/6876 , C12Q2600/158
摘要： The present invention relates to isolated and/or purified rat apoptosis-specific eucaryotic initiation Factor-5A (eIF-5A) and deoxyhypusine synthase (DHS) nucleic acids and polypeptides. The present invention also relates to methods of modulating apoptosis using apoptosis-specific eIF-5A and DHS, and antisense oligonucleotides and expression vectors of apoptosis-specific eIF-5A and DHS useful in such methods.
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