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    SURGICAL DEVICE FOR PROVIDING ACCESS TO A SURGICAL SITE
    31.
    发明授权
    SURGICAL DEVICE FOR PROVIDING ACCESS TO A SURGICAL SITE 有权
    用于提供进入手术部位的手术装置

    公开(公告)号：EP3007630B1

    公开(公告)日：2017-08-30

    申请号：EP14736651.2

    申请日：2014-06-12

    申请人： UMC Utrecht Holding B.V.

    发明人： GRÜNDEMAN, Paul Frederik ,  KWANT, Paul Barteld

    IPC分类号： A61B17/02 ,  A61B17/34 ,  A61B17/00

    CPC分类号： A61B17/0218 ,  A61B5/0422 ,  A61B5/6847 ,  A61B5/6865 ,  A61B90/02 ,  A61B2017/00557 ,  A61B2017/0225 ,  A61B2017/0237 ,  A61B2090/306

    摘要： A surgical device (5) for application in a treatment performed on the human or animal body (1) with the aim of providing access to a surgical site in the body, includes at least one inflatable chamber (70, 71, 72) which can be inflated from a collapsed state to an expanded state, in which expanded state the device is suitable for exerting a force on an organ or tissue at the surgical site, at least one elongated flexible member (8, 80), which member at its proximal end (801) is operatively connected to the device, and which member has a length to allow the distal end (800) of the member to be fixed to a fixation site (100, 101) outside of the body, and methods of using this device.

    摘要翻译： 为了提供进入体内手术部位的目的，用于在人体或动物体（1）上进行治疗的手术装置（5）包括至少一个可充气腔室（70,71,72），所述可充气腔室 从收缩状态膨胀到扩张状态，在该扩张状态中，该装置适于在手术部位处的器官或组织上施加力;至少一个细长柔性构件（8,80），该构件在其近侧 端部801可操作地连接到所述装置，并且所述构件具有允许所述构件的远端800固定到所述主体外部的固定部位100,101的长度， 设备。

    IMMUNOGLOBULIN-LIKE MOLECULES DIRECTED AGAINST FIBRONECTIN-EDA
    32.
    发明公开
    IMMUNOGLOBULIN-LIKE MOLECULES DIRECTED AGAINST FIBRONECTIN-EDA 审中-公开
    IMMUNOGLOBULINÄHNLICHEMOLEKÜLEGEGEN FIBRONECTIN-EDA

    公开(公告)号：EP3080163A1

    公开(公告)日：2016-10-19

    申请号：EP14828328.6

    申请日：2014-12-12

    申请人： UMC Utrecht Holding B.V.

    发明人： ARSLAN, Fatih

    IPC分类号： C07K16/18 ,  A61P9/10

    摘要： The present invention is concerned with immunoglobulin (Ig)-like molecules or fragments thereof for use in treatment, prevention, or prevention of progression of adverse cardiac remodelling and conditions resulting from or relating to myocardial infarction and pressure-overload, such as heart failure, aneurysm formation and remote myocardial fibrosis and for use in improving angiogenesis, preferably after ischemic injury. The invention also provides nucleic acid molecules encoding said Ig-like molecules, vectors comprising same, and host cells comprising same.

    摘要翻译： 本发明涉及用于治疗，预防或预防不良心脏重塑进展的免疫球蛋白（Ig）样分子或其片段，以及由心肌梗塞和压力过载引起的或与其相关的病症，例如心力衰竭， 动脉瘤形成和远端心肌纤维化，并用于改善血管发生，优选在缺血性损伤后。 本发明还提供了编码所述Ig样分子的核酸分子，包含其的载体和包含其的宿主细胞。

    A DEVICE AND METHOD FOR RADIOGRAPHIC AND NUCLEAR IMAGING OF AN OBJECT
    35.
    发明公开
    A DEVICE AND METHOD FOR RADIOGRAPHIC AND NUCLEAR IMAGING OF AN OBJECT 审中-公开
    VORRICHTUNG UND VERFAHREN ZUR RADIOGRAPHISCHEN UND NUKLEAREN ABBILDUNG EINES OBJEKTS

    公开(公告)号：EP2931128A1

    公开(公告)日：2015-10-21

    申请号：EP13818485.8

    申请日：2013-12-12

    申请人： UMC Utrecht Holding B.V.

    发明人： DE JONG, Hugo Wilhelmus Antonius Maria

    IPC分类号： A61B6/03 ,  A61B6/00

    CPC分类号： A61B6/032 ,  A61B6/037 ,  A61B6/12 ,  A61B6/4258 ,  A61B6/4291 ,  A61B6/4417 ,  A61B6/4441 ,  A61B6/5235 ,  A61B6/5247

    摘要： A method and device, e.g. a C-arm device, for radiographic and nuclear imaging of an object by means of x-ray and gamma emission imaging. The device comprises a support installation with opposed first and second support members, wherein an x-ray source is mounted on the first support member and an x-ray detector on the second support member. The first support member is additionally provided with at least two gamma cameras that are each located adjacent the x-ray source. Each of said at least two gamma cameras comprising a collimator with one or more collimator openings and a gamma radiation detector. Each of the at least two gamma cameras has an associated field of view. The fields of view of the gamma cameras overlap partly, said overlap defining a focus volume that is seen by the at least two gamma cameras. The focus volume is located between the x-ray source and the x-ray detector so that the x-ray beam passes through the focus volume and the focus volume F is seen by the x-ray detector. The x-ray source, x-ray detector, and gamma cameras are maintained in a stationary acquisition position during x-ray and gamma image data acquisition of x-ray and gamma radiation images respectively, which images are fused into a fused image.

    摘要翻译： 一种方法和装置，例如 C臂装置，用于通过x射线和γ射线成像对物体进行射线照相和核成像。 该装置包括具有相对的第一和第二支撑构件的支撑装置，其中x射线源安装在第一支撑构件上，并且X射线检测器安装在第二支撑构件上。 第一支撑构件另外设置有至少两个伽马照相机，每个伽马照相机各自位于x射线源附近。 所述至少两个伽马照相机中的每一个包括具有一个或多个准直仪开口的准直仪和伽马射线检测器。 所述至少两个伽马照相机中的每一个具有相关的视野。 γ摄像机的视野部分地重叠，所述重叠限定由至少两个伽马照相机所看到的焦点体积。 聚焦体积位于x射线源和X射线探测器之间，以便X射线束通过焦点体积，并且X射线检测器可以看到焦距体积F. X射线源，X射线检测器和γ照相机分别在x射线和伽马图像数据采集X射线和伽马射线图像期间保持在静止采集位置，这些图像被融合到融合图像中。

    HOLDING DEVICE FOR HOLDING A MANUALLY OPERATED MEDICAL DEVICE
    39.
    发明公开
    HOLDING DEVICE FOR HOLDING A MANUALLY OPERATED MEDICAL DEVICE 审中-公开
    夹持装置，用于保持手动OPERATED医疗器械

    公开(公告)号：EP2485673A1

    公开(公告)日：2012-08-15

    申请号：EP09741027.8

    申请日：2009-10-07

    申请人： UMC Utrecht Holding B.V.

    发明人： JASPERS, Joris, Emanuel, Nicolaas ,  BOSMA, Jesse, Mattan

    IPC分类号： A61B19/00 ,  A61B17/34

    CPC分类号： A61B17/3421 ,  A61B34/70 ,  A61B90/50 ,  A61B2017/347

    摘要： Holding device for holding a manually operated medical device in place, comprising: a connector arranged to connect the holding device to a positioning apparatus; a clamp member arranged to clamp the medical device, wherein the clamp member is moveable between a locking position wherein the medical device is clamped and a moving position wherein the medical device is moveable with respect to the holding device; a joint assembly arranged to allow movement between the clamp member and the connector, wherein the joint assembly is moveable between a moving position wherein the clamp member is moveable with respect to the connector and a locking position wherein movement between the clamp member and the connector is prevented, and; an actuator for moving both the joint assembly and the clamp member between the moving positions and the locking positions.