-
31.发明公开9-ALPHA ESTRATRIENE DERIVATIVES AS ER-BETA SELECTIVE LIGANDS FOR THE PREVENTION AND TREATMENT OF INTESTINAL CANCER 审中-公开9-α-雌三烯衍生物作为癌症的预防和治疗ER-β选择性配体
公开(公告)号：EP2318009A1
公开(公告)日：2011-05-11
申请号：EP09777170.3
申请日：2009-07-09
IPC分类号： A61K31/565 , A61K31/567 , A61P35/00
CPC分类号： A61K31/565 , A61K31/567
摘要： Use of 9α-estra-1,3,5(10)-triene derivatives of formula (I) for the prevention and treatment of intestinal cancer, in particular adenoma and adenocarcinoma of the duodenum, ileum, colon, and rectum.
-
公开(公告)号：EP2291369A4
公开(公告)日：2011-05-11
申请号：EP09750866
申请日：2009-05-20
发明人： BERGER MARKUS , DAHMEN JAN , EDMAN KARL , ERIKSSON ANDERS , HANSSON THOMAS , HEMMERLING MARTIN , HOSSAIN NAFIZAL , KLINGSTEDT PER THOMAS , LEPISTÖ MATTI , NILSSON STINABRITT , REHWINKEL HARTMUT
IPC分类号： C07D409/14 , A61K31/416 , A61K31/4439 , A61P11/00 , A61P29/00 , C07D407/12 , C07D407/14
CPC分类号： C07D409/14 , A61K31/416 , A61K31/4439 , A61K45/06 , C07D231/56 , C07D401/12 , C07D401/14 , C07D403/10 , C07D403/12 , C07D405/10 , C07D405/12 , C07D405/14 , C07D407/14 , C07D409/12 , C07D413/12
-
公开(公告)号：EP2291359A4
公开(公告)日：2011-05-11
申请号：EP09750864
申请日：2009-05-20
发明人： BAYER SCHERING PHARMA AG , BERGER MARKUS , DAHMEN JAN , EDMAN KARL , HANSSON THOMAS , HEMMERLING MARTIN , HOSSAIN NAFIZAL , JOHANSSON HENRIK , LEPISTOE MATTI , NILSSON STINABRITT , REHWINKEL HARTMUT
IPC分类号： C07D231/56 , A61K31/416 , A61K31/422 , A61K31/4439 , A61K31/444 , A61P11/00 , A61P29/00 , C07D401/12 , C07D401/14 , C07D403/10 , C07D403/12 , C07D407/14 , C07D409/12 , C07D409/14 , C07D413/12
CPC分类号： C07D409/14 , A61K31/416 , A61K31/4439 , A61K45/06 , C07D231/56 , C07D401/12 , C07D401/14 , C07D403/10 , C07D403/12 , C07D405/10 , C07D405/12 , C07D405/14 , C07D407/14 , C07D409/12 , C07D413/12
-
公开(公告)号：EP2291359A1
公开(公告)日：2011-03-09
申请号：EP09750864.2
申请日：2009-05-20
发明人： BAYER SCHERING PHARMA AG , BERGER, Markus , DAHMEN, Jan , EDMAN Karl , HANSSON, Thomas , HEMMERLING, Martin , HOSSAIN, Nafizal , JOHANSSON, Henrik , LEPISTÖ, Matti , NILSSON, Stinabritt , REHWINKEL, Hartmut
IPC分类号： C07D231/56 , A61K31/416 , A61K31/422 , A61K31/4439 , A61K31/444 , A61P11/00 , A61P29/00 , C07D401/12 , C07D401/14 , C07D403/10 , C07D403/12 , C07D407/14 , C07D409/12 , C07D409/14 , C07D413/12
CPC分类号： C07D409/14 , A61K31/416 , A61K31/4439 , A61K45/06 , C07D231/56 , C07D401/12 , C07D401/14 , C07D403/10 , C07D403/12 , C07D405/10 , C07D405/12 , C07D405/14 , C07D407/14 , C07D409/12 , C07D413/12
摘要： A compound of formula Ia: Formula (la) The present invention relates to novel indazolyl derivatives, to pharmaceutical compositions comprising such derivatives, to processes for preparing such novel derivatives and to the use of such derivatives as medicaments.
摘要翻译： 式Ia化合物：本发明涉及新的吲唑基衍生物，包含这些衍生物的药物组合物，制备这种新衍生物的方法以及使用这些衍生物作为药物
-
公开(公告)号：EP2285443A2
公开(公告)日：2011-02-23
申请号：EP09739927.3
申请日：2009-05-01
发明人： EWING, Benjamin, T. , BRUCKER, Gregory, G. , BEDNAR, Scott, A. , PERIARD, John, R. , SHARMA, Ashok, K. , SAVAGE, Steven, D. , UBER, Arthur, E., III , DICKERSON, Brian, P.
IPC分类号： A61M25/10
CPC分类号： A61M25/104 , A61B17/22 , A61B2017/22001 , A61B2017/22051 , A61B2017/22061 , A61L29/08 , A61L29/16 , A61L2420/02 , A61M25/1002 , A61M25/1029 , A61M25/1038 , A61M2025/1004 , A61M2025/1031 , A61M2025/105 , A61M2025/1075 , A61M2210/12 , Y10T29/49826
摘要： Various methods for optimizing coating of medical devices, such as balloon catheters are disclosed. One method configures catheter balloon folds based on balloon diameter and volume. Other methods include using a specifically-sized protective sheath, using a vacuum, using pressure, pulling the balloon through a coating solution, using at least one spacer or a wick between at least one fold for metering a therapeutic coating into the folds of the balloon, placing an intermediate layer between the balloon and the therapeutic coating, placing a soluble film having a therapeutic agent around the catheter balloon or inside the folds, and any combination thereof. Balloon catheters and catheter balloons having a specific folding configuration, a specifically-sized protective sheath, an intermediate layer, or a soluble film are also disclosed.
-
36.发明公开SULFONE SUBSTITUTED 2,3-DIHYDROIMIDAZO Ý1,2-C¨QUINAZOLINE DERIVATIVES USEFUL FOR TREATING HYPER-PROLIFERATIVE DISORDERS AND DISEASES WITH ANGIOGENESIS 审中-公开SULFONSUBSTITUIERTE -2,3-二氢咪唑并[1,2-C] -CHINAZOLINDERIVATE用于治疗过度增生病症和疾病血管生成
公开(公告)号：EP2244721A2
公开(公告)日：2010-11-03
申请号：EP09702696.7
申请日：2009-01-13
发明人： HENTEMANN, Martin, F. , SCOTT, William , WOOD, Jill , JOHNSON, Jeffrey , REDMAN, Aniko , BULLION, Ann-marie , GUERNON, Leatte
IPC分类号： A61K38/16
CPC分类号： A61K45/06 , A61K31/519 , A61K31/541 , A61K2300/00 , C07D487/04
摘要： This invention relates to novel sulfone 2I3-dihydroimidazo[1 l2-c]quinazoline compounds, pharmaceutical compositions containing such compounds and the use of those compounds or compositions for phosphotidylinositol-3-kinase (PI3K) inhibition and treating diseases associated with phosphotidylinositol-3-kinase (PI3K) activity, in particular treating hyper-proliferative and/or angiogenesis mediated disorders, as a sole agent or in combination with other active ingredients.
摘要翻译： 本发明涉及新的砜2I3二氢〔1 L2-C]喹唑啉化合物，药物组合物含有受试化合物和磷脂酰肌醇-3-激酶（PI3K）的抑制使用这些化合物或组合物和治疗疾病的磷脂酰肌醇3相关联 激酶（PI3K）活性，特别是治疗过度增殖和/或血管生成介导的疾病，作为唯一的药物或与其它活性成分组合。
-
公开(公告)号：EP2216056A1
公开(公告)日：2010-08-11
申请号：EP10163587.8
申请日：2003-08-26
发明人： Speck, Ulrich , Scheller, Bruno
CPC分类号： A61M25/1002 , A61L29/08 , A61L29/085 , A61L29/16 , A61L31/08 , A61L31/16 , A61L2300/41 , A61L2300/412 , A61L2300/416 , A61L2300/43 , A61M25/0045 , A61M25/10 , A61M25/1027 , A61M25/1038 , A61M25/104 , A61M2025/0057 , A61M2025/1004 , A61M2025/1031 , A61M2025/105 , A61M2025/1075 , A61M2025/1086
摘要： Die Erfindung betrifft eine medizinische Vorrichtung zur Arzneimittelabgabe für die selektive Therapie bestimmter Gewebeabschnitte und Organteile und ein Verfahren zur Herstellung derartiger arzneimittelbeschichteter Geräte.
摘要翻译： 本发明涉及一种用于药物递送的用于组织和器官份某些部分的选择性疗法和用于制造这样的药物涂覆的装置的方法的医疗装置。
-
38.发明公开PYRROLO[2,1-F] [1,2,4] TRIAZIN-4-YLAMINES IGF-1R KINASE INHIBITORS FOR THE TREATMENT OF CANCER AND OTHER HYPERPROLIFERATIVE DISEASES 有权吡咯并[2,1-F] [1,2,4]三嗪-4-基胺IGF-1R激酶抑制剂的用于治疗癌症和其它疾病的过度增殖于治疗
公开(公告)号：EP1945222A4
公开(公告)日：2010-01-06
申请号：EP06836894
申请日：2006-11-02
发明人： O'CONNOR STEPHEN J , DUMAS JACQUES , LEE WENDY , DIXON JULIE , CANTIN DAVID , GUNN DAVID , BURKE JENNIFER , PHILLIPS BARTON , LOWE DEREK , SHELEKHIN TATIANA , WANG GAN , MA XIN , YING SHIHONG , MCCLURE ANDREA , ACHEBE FURAHI , LOBELL MARIO , EHRGOTT FREDERICK , IWUAGWU CHRISTIANA , PARCELLA KYLE
CPC分类号： C07D487/04
-
39.发明公开
公开(公告)号：EP2097384A4
公开(公告)日：2009-12-30
申请号：EP07835228
申请日：2007-11-22
发明人： BERGER MARKUS , BERGSTROEM LENA , DAHMEN JAN , ERIKSSON ANDERS , GABOS BALINT , HEMMERLING MARTIN , HENRIKSSON KRISTER , IVANOVA SVETLANA , LEPISTOE MATTI , MCKERRECHER DARREN , NILSSON STINABRITT , REHWINKEL HARTMUT , TAFLIN CAMILLA
IPC分类号： C07D231/56 , A61K31/416 , A61K31/454 , A61K31/4545 , A61P11/00 , A61P29/00 , A61P35/00 , A61P37/06 , A61P37/08 , C07D401/04 , C07D401/14
CPC分类号： C07D231/56 , C07D401/04 , C07D401/12 , C07D401/14 , C07D403/12 , C07D405/12 , C07D413/12
-
40.发明公开USE OF EPOTHILONES IN THE TREATMENT OF OSTEOPOROSIS AND RELATED DISEASES 审中-公开EPITHILONEN的骨质疏松症及相关疾病治疗中的应用
公开(公告)号：EP2101765A1
公开(公告)日：2009-09-23
申请号：EP07856543.9
申请日：2007-12-05
发明人： HOFFMANN, Jens , KÄKÖNEN, Sanna , KLAR, Ulrich
IPC分类号： A61K31/427 , A61P19/10
CPC分类号： A61K31/427
摘要： The present invention relates to the use of natural or synthetic Epothilones for the treatment prevention or alleviation of diseases caused by a dysbalance of osteoclast and osteoblast activity, especially osteoporosis.
-
-
-
-
-
-
-
-
-
搜索结果
82 条记录 (耗时 0.026 秒)
