公开(公告)号：EP0659091A1

公开(公告)日：1995-06-28

申请号：EP93919750.0

申请日：1993-08-12

申请人： GAMBRO AB

发明人： ARVIDSSON, Lars ,  JÖNSSON, Jörgen ,  MAKI, Gerry, Cobe Canada Ltd.

IPC分类号： A61J3 ,  A61M1

CPC分类号： A61M1/169 ,  A61M1/1686 ,  A61M1/1688

摘要： A system for preparation of a medical solution, such as for dialysis, hemodiafiltration or hemofiltration, comprising a preferably conventional control monitor (1) with an input (2) for concentrate and a recirculation circuit (15) connectable to said input for chemical and/or heat sterilisation and/or other cleansing of at least the liquid preparation circuit of the control monitor. The system is characterized by a cleansing chamber (10, 10') connectable to the recirculation circuit (15), which chamber is arranged to be able to receive a concentrate suction pipe (5) which is disconnectable from the monitor (1) so that said pipe may be flushed. The invention also relates to a method for sterilizing a concentrate suction pipe (5) forming a part of the above mentioned system. The invention further includes a cleansing chamber (10) intended to be included in the system.

公开(公告)号：EP0428009B1

公开(公告)日：1994-10-05

申请号：EP90120851.2

申请日：1990-10-31

申请人： GAMBRO AB

发明人： Lindqvist, Sten-Börje ,  Nystrand, Rolf

IPC分类号： A61M1/14 ,  A61L2/04

CPC分类号： A61M1/1656 ,  A61L2/0023 ,  A61L2/04 ,  A61M1/166 ,  A61M1/1662 ,  A61M1/1666 ,  A61M1/1686

公开(公告)号：EP0330892B1

公开(公告)日：1994-07-06

申请号：EP89102407.7

申请日：1989-02-11

申请人： GAMBRO AB

发明人： Sternby, Jan Peter

IPC分类号： A61M1/14

CPC分类号： A61M1/16 ,  A61M1/1607 ,  A61M1/1609 ,  A61M1/1617 ,  A61M1/1647 ,  A61M1/165 ,  A61M1/1664 ,  A61M2205/3317 ,  A61M2205/3324 ,  A61M2205/3334 ,  A61M2205/3368 ,  A61M2205/50

公开(公告)号：EP0498080A3

公开(公告)日：1993-04-14

申请号：EP91122408.7

申请日：1991-12-31

申请人： GAMBRO AB

发明人： Bertinsson, Gert-Inge ,  Mattisson, Leif ,  Ohlsson, Göran

IPC分类号： G01F15/12

CPC分类号： G01F15/12 ,  G01F1/584

摘要： Measuring device including at least one measuring electrode (3-6) arranged in a conduit (1, 2) through which a liquid is intended to be flowed which can cause depositions on the electrode. The device is characterized by means (7, 8, 11) for connecting the measuring electrode (3-6) as an electrode in an electrolytic cell including a second electrode (13, 14 or 3-6), and by means for applying a voltage between these electrodes for cleansing of the measuring electrode. The invention also relates to a method of cleansing a measuring electrode, characterized in that the cleansing occurs with the help of said means (7, 8, 11).

公开(公告)号：EP0472480A1

公开(公告)日：1992-02-26

申请号：EP91420294.0

申请日：1991-08-14

申请人： HOSPAL INDUSTRIE ,  GAMBRO AB

发明人： Chevallet, Jacques ,  Riquier, Jean-Claude ,  Örndal, Carl-Henry ,  Petersen, Allan

IPC分类号： A61M1/30 ,  A61M1/34

CPC分类号： A61M1/30 ,  A61M1/302 ,  A61M1/303 ,  A61M1/308 ,  A61M2205/3382 ,  A61M2205/3386

摘要： In a blood treatment apparatus, a circuit for circulating blood outside the body and designed to be connected to a patient via a single needle (7) comprises a blood treatment device proper (1), blood circulation means (8, 9) for causing blood to flow through the circuit, at least one blood expansion chamber ( 12, 21 ), and pressure regulation means (18, 25) for maintaining an adjustable pressure substantially constant at least downstream from the blood treatment device (1).

摘要翻译： 在血液处理装置中，用于使体外循环血液并设计成经由单个针（7）连接到患者的电路包括血液处理装置本体（1），用于引起血液的血液循环装置（8,9） 流过所述回路，至少一个血液扩张室（12,21）和压力调节装置（18,25），用于保持血液处理装置（1）的至少下游基本恒定的可调节压力。

公开(公告)号：EP0458041A1

公开(公告)日：1991-11-27

申请号：EP91105180.3

申请日：1991-04-02

申请人： GAMBRO AB

发明人： Felding, Anders

IPC分类号： A61M1/14

CPC分类号： A61M1/169 ,  A61M1/1666 ,  A61M1/168 ,  A61M1/1682 ,  A61M1/1686 ,  A61M1/1688 ,  A61M2209/082

摘要： System for controlling a medical treatment, for example dialysis, using a preferably heated treatment fluid, comprising means (18,28) for controlling the flow of the fluid through the system and means (36,37) for connecting the system to a treatment device, for example a dialyzer (33), whereby disinfection and/or sterilization and/or other cleansing of the system is effected with the aid of a liquid which is made to flow along the same path as the treatment fluid, except that it is diverted past the treatment device by means of a so called by-pass arrangement (38-41 and/or 34,35).
The system according to the invention is characterized by means for connecting a cartridge or other vessel (1' ,1'' or 1''') to a conduit (1,12,17) in the system, wherein the cartridge or vessel contains a soluble concentrate in liquid or powder form, preferably powder form, which achieves or at least aids the said cleansing, and by means (1a) for supplying water or another solvent to said conduit (1) to flow through and dissolve the concentrate.

摘要翻译： 用于控制医疗处理的系统，例如使用优选加热的治疗流体的透析，包括用于控制通过系统的流体流动的装置（18,28）和用于将系统连接到治疗装置的装置（36,37） ，例如透析器（33），其中借助于沿着与治疗流体相同的路径流动的液体来实现系统的消毒和/或灭菌和/或其它清洁，除了它被转移 通过所谓的旁路安排（38-41和/或34,35）经过治疗装置。 根据本发明的系统的特征在于用于将盒或其它容器（1'，1“或1”）连接到系统中的导管（1,12,17）的装置，其中盒或容器包含 液体或粉末形式的可溶性浓缩物，优选粉末形式，其实现或至少有助于所述清洁，以及通过用于向所述导管（1）供应水或另一种溶剂的装置（1a）以流过并溶解浓缩物。

公开(公告)号：EP0223126B1

公开(公告)日：1991-10-09

申请号：EP86115019.1

申请日：1986-10-29

申请人： GAMBRO AB

发明人： Solem, Jan Otto ,  Pilman, Olev Hugo

IPC分类号： A61M1/34

CPC分类号： A61M1/34 ,  A61M1/3603 ,  A61M1/3692

公开(公告)号：EP0439793A2

公开(公告)日：1991-08-07

申请号：EP90124890.6

申请日：1990-12-20

申请人： GAMBRO AB

发明人： Hallberg, Birger ,  Olsson, Lennart

IPC分类号： A61M1/16

CPC分类号： A61M1/1656 ,  A61M1/1666 ,  A61M1/1668 ,  A61M1/167 ,  A61M1/287 ,  A61M1/3462

摘要： Tube arrangement, including means (11, 12) for connection to a water source (15), a powder cartridge (9) or means (22'') for connection of a powder cartridge and means (7) for connection to a monitor for preparation of a medical solution, for example dialysis fluid, replacement fluid for haemofiltration or fluid for peritoneal dialysis.
The tube set according to the invention is characterized by means (10; 10', 8a', 8b'; 10'', 10''', 8a, 8b) for lowering the water pressure to substantially atmospheric pressure.
The invention also relates to a process for supplying a powder concentrate to a monitor (1) for preparation of a medical solution for example a dialysis solution, replacement fluid for haemofiltration or dialysis fluid for peritoneal dialysis, whereby the powder concentrate is supplied instead of a concentrate in liquid form, which the monitor is arranged to normally take from a vessel at atmospheric pressure.
The process according to the invention is characterized in that the powder is dissolved by the through-flow of water from a water source whereby the dissolving occurs substantially at atmospheric pressure, which pressure is also maintained during the subsequent transportation to the monitors normal intake of concentrate.

摘要翻译： 管装置，包括装置（11，12），用于连接到水源（15），粉末盒（9）或装置（22“”），用于（7），用于连接到监视器用于粉末盒和手段的连接 制备的医用溶液，例如透析液，置换液为用于腹膜血液过滤或透析液。 管道组gemäß的发明是由意指特征（10; 10“ 8A”，8B“ 10' ”，10' ”，8A，8B），用于降低水的压力基本上为大气压力。 因此本发明涉及一种方法，用于供给粉末浓缩物的监视器（1）在制备用于实施例的医用溶液透析溶液，用于腹膜透析滤过或透析液置换液，由此，粉末浓缩物是用提供的，而不是 浓缩液体形式，其中监视器被设置为从通常在大气压力下的容器中采取。 过程雅丁于本发明中DASS模粉末的特征在于，通过在氮气下将通流的水从水源，由此溶解在大气压力下，该压力在随后运输到监视器正常摄入浓缩物的过程中，因此基本上保持发生 ，

公开(公告)号：EP0432138A2

公开(公告)日：1991-06-12

申请号：EP91102527.8

申请日：1986-05-28

申请人： GAMBRO AB

发明人： Bjäre, Björn Ake ,  Eckerbom, Anders Gustav ,  Gummesson, Bengt-Ake Göran ,  Sternby, Jan Peter

IPC分类号： G05B19/10 ,  A61M1/16

CPC分类号： G05B19/104 ,  A61M1/16 ,  A61M2205/17 ,  G05B19/108 ,  G05B2219/2214 ,  G05B2219/23138 ,  G05B2219/23157 ,  G05B2219/23165 ,  G05B2219/23215 ,  G05B2219/25114 ,  G05B2219/25384 ,  G06F19/00

摘要： A control panel is described for use with a system having means for regulating a plurality of parameters (xxx,yyy) according to at least one control constant associated with each parameter, said control constants including a critical constant, the control panel comprising: manually controllable input means (6) for manually setting new values (e g 7a,8a) of said control constants and supplying said manually selected new values of said control constants to said system.
The control panel according to the invention is intended primarily for the control of hemodialysis, that is to say the purification of the blood of patients with diminished renal function or wholly lacking such function.
The control panel according to the invention is characterized by comparison and substitution means (40) for comparing said manually selected new value supplied by said manually controllable input means (6) for said critical constant with a predetermined range (e g 7c-7d,8c-8d) defined by upper and lower bounding values for said critical constant and supplying to said system a new value of said critical constant within said predetermined range in place of said manually selected new value when said manually selected new values supplied by said manually controllable input means (6) is above said upper bounding value (7d,8d) or below said lower bounding value (7c,8c).

摘要翻译： 控制面板被描述为与具有用于根据与每个参数相关联的至少一个控制常数调节多个参数（xxx，yyy）的装置的系统一起使用，所述控制常数包括临界常数，所述控制面板包括：可手动控制的 输入装置（6），用于手动设置所述控制常数的新值（例如7a，8a），并将所述控制常数的所述手动选择的新值提供给所述系统。 根据本发明的控制组主要用于控制血液透析，也就是说肾脏功能降低或完全缺乏这种功能的患者的血液的净化。 根据本发明的控制面板的特征在于比较和替换装置（40），用于将由所述手动可控输入装置（6）提供的所述手动选择的新值与所述临界常数与预定范围（例如7c-7d，8c- 8d），并且当由所述手动控制的输入装置提供的所述手动选择的新值时，在所述预定范围内向所述系统提供所述临界常数的新值来代替所述手动选择的新值 （6）高于所述上限值（7d，8d）或低于所述下限值（7c，8c）。

公开(公告)号：EP0428009A1

公开(公告)日：1991-05-22

申请号：EP90120851.2

申请日：1990-10-31

申请人： GAMBRO AB

发明人： Lindqvist, Sten-Börje ,  Nystrand, Rolf

IPC分类号： A61M1/14 ,  A61L2/04

CPC分类号： A61M1/1656 ,  A61L2/0023 ,  A61L2/04 ,  A61M1/166 ,  A61M1/1662 ,  A61M1/1666 ,  A61M1/1686

摘要： A method for the preparation of a sterile dialysis fluid for medical use or a similar physiologically acceptable sterile fluid by which method water is continuously transported from a source (A) for the same to a point of consumption (G), necessary concentrates in liquid and/or powder form being added during the transport.
The method according to the invention is characterized in that the water with or without concentrate is heated during the transport to sterilization temperature and is kept at this temperature during the time required for the sterilization, whereafter it is cooled to the desired consuming temperature.
The invention also relates to a system for the prepara­tion of a sterile dialysis fluid or a similar physiologically acceptable fluid by means of the above method, comprising a pipeline between the said source for the water (A) and the point of consumption (G), e g a draw-off point, this pipeline compri­sing means (8,8′) for the pumping of water, means (3) for its heating, means (2,6) for its cooling and means (eg 21 and 23) for the supply of necessary concentrates in liquid and/or powder form.
The system according to the invention is characterized in that the pipeline between the said means (3 and 2,6) for heating and cooling respectively of water is dimensioned so in relation to the capacity of the said means (8,8′ and 3) for pumping and heating respectively that the sojourn time of the water within this part X-Y of the pipeline will be sufficient for the steri­lization.

摘要翻译： 一种用于医疗用途或类似的生理上可接受的无菌流体通过该方法水连续从源（A）运对于相同的点消费（G）在液体浓缩物必要和无菌透析液的制备方法 /或粉末形式的运输过程中加入。 在具有或不浓缩物输送到杀菌温度时被加热，并在用于灭菌所需的时间保持在该温度，之后将其冷却至期望的温度消耗做的水的方法，雅丁到本发明的特征。 因此本发明涉及一种用于无菌透析液或者通过上述方法的手段类似的生理上可接受的流体的制备中的系统中，包含所述源极之间的管道的水（A）和消费点（G） EGA取水点，该流水线包括：装置（8.8分钟）的水泵，装置（3），用于其加热的装置（2.6），用于其冷却的装置（例如21和23），用于供应 必要在液体和/或粉末形式的浓缩物。该系统gemäß于本发明中所述装置之间（和2.6 3）DASS模具管道用于加热，其特征在于分别的冷却水的尺寸使得相对于容量 所述的装置（8.8分钟，3），用于泵送和加热分别做了水的滞留时间的XY管道的该部分内将是足够的灭菌。