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公开(公告)号:EP3634500A1
公开(公告)日:2020-04-15
申请号:EP18729255.2
申请日:2018-05-17
发明人: BRADBURY, Michelle S. , CHEN, Feng , WIESNER, Ulrich , MA, Kai
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公开(公告)号:EP3630095A1
公开(公告)日:2020-04-08
申请号:EP18809263.9
申请日:2018-06-04
IPC分类号: A61K31/395 , A61K31/4015 , A61K31/4025 , A61K39/395 , C07K16/28
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公开(公告)号:EP2760525B1
公开(公告)日:2020-04-08
申请号:EP12835312.5
申请日:2012-10-01
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34.
公开(公告)号:EP3624818A1
公开(公告)日:2020-03-25
申请号:EP18802196.8
申请日:2018-05-15
发明人: BECATTINI, Simone , PAMER, Eric , KIM, Sohn
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公开(公告)号:EP3233134B1
公开(公告)日:2020-03-25
申请号:EP15820752.2
申请日:2015-12-15
发明人: BRADBURY, Michelle S. , YOO, Barney , WIESNER, Ulrich , CHEN, Peiming , MA, Kai , PATEL, Snehal G. , ZANONI, Daniella Karassawa
IPC分类号: A61K49/00
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公开(公告)号:EP3621646A1
公开(公告)日:2020-03-18
申请号:EP18798012.3
申请日:2018-05-11
发明人: DENG, Liang , SHUMAN, Stewart , YANG, Ning , MERGHOUB, Taha , WOLCHOK, Jedd
IPC分类号: A61K39/285 , C12N15/863
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公开(公告)号:EP3620521A1
公开(公告)日:2020-03-11
申请号:EP19185730.9
申请日:2015-09-04
发明人: SADELAIN, Michel , RIVIERE, Isabelle , MANSILLA-SOTO, Jorge , WANG, Xiuyan , STAMATOYANNOPOULOS, George , STAMATOYANNOPOULOS, John , LIU, Mingdong
IPC分类号: C12N15/113 , A61K48/00 , C12N15/85 , C12N15/867
摘要: The presently disclosed subject matter provides for expression cassettes that allow for expression of a globin gene or a functional portion thereof, vectors comprising thereof, and cells transduced with such expression cassettes and vectors. The presently disclosed subject matter further provides methods for treating a hemoglobinopathy in a subject comprising administering an effective amount of such transduced cells to the subject.
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公开(公告)号:EP3612211A1
公开(公告)日:2020-02-26
申请号:EP18787923.4
申请日:2018-04-17
申请人: Memorial Sloan-Kettering Cancer Center , Klinikum rechts der Isar der Technischen Universität München
IPC分类号: A61K38/20 , A61K39/39 , A61K31/7084 , C07K14/54
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公开(公告)号:EP3151854B1
公开(公告)日:2020-02-26
申请号:EP15803100.5
申请日:2015-06-05
申请人: Memorial Sloan Kettering Cancer Center , The United States of America, as represented by The Secretary, Department of Health and Human Services
IPC分类号: A61K35/00 , A61K38/00 , A61K39/00 , C07K14/47 , C07K14/705 , C07K14/725 , C07K16/28 , C07K16/30
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公开(公告)号:EP3600360A1
公开(公告)日:2020-02-05
申请号:EP18770878.9
申请日:2018-03-21
发明人: STUDER, Lorenz , TCHIEU, Jason
IPC分类号: A61K35/30 , C12N5/0789 , C12N5/079 , C12N5/0793 , C12N5/0797 , G01N33/50
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