-
公开(公告)号:EP3766506B1
公开(公告)日:2024-09-11
申请号:EP19766786.8
申请日:2019-01-30
CPC classification number: A61K35/30 , A61P9/00 , A61K35/44 , C12N5/0623 , C12N2500/0220130101 , C12N2533/9020130101 , A61P25/28
-
公开(公告)号:EP3056564B2
公开(公告)日:2024-09-11
申请号:EP14852053.9
申请日:2014-10-09
CPC classification number: C12N2506/4520130101 , C12N2533/5220130101 , A61K35/30 , C12N5/0621 , A61P27/02
-
公开(公告)号:EP4419688A2
公开(公告)日:2024-08-28
申请号:EP22884709.1
申请日:2022-10-20
Applicant: Prime Medicine, Inc.
Inventor: YEH, Wei Hsi
CPC classification number: C12N2310/2020170501 , C12N2310/351920130101 , C12N2320/3420130101 , C12N15/1138 , C12N2310/31520130101 , C12N2310/34420130101 , C12N2740/1604320130101 , C12N15/907
-
4.
公开(公告)号:EP4419119A1
公开(公告)日:2024-08-28
申请号:EP22806097.6
申请日:2022-10-19
Applicant: University of Rochester , University of Copenhagen
Inventor: GOLDMAN, Steven , DA COSTA BARBEDO VIEIRA, Ricardo
-
5.
公开(公告)号:EP4410962A1
公开(公告)日:2024-08-07
申请号:EP22876261.3
申请日:2022-09-27
Applicant: Sumitomo Pharma Co., Ltd. , National University Corporation Tokai National Higher Education and Research System , Sumitomo Chemical Company, Limited
Inventor: TAGA, Shiori , KUWAHARA, Atsushi , SUGA, Hidetaka , NAKANO, Tokushige
IPC: C12N5/071 , A61K35/12 , A61K35/30 , A61K35/545 , A61P5/10 , C12N5/0735 , C12N5/079
CPC classification number: A61K35/545 , A61P5/10 , A61K35/30 , A61K35/12 , C12N5/06
Abstract: The present invention provides a method for efficiently producing a cell aggregate containing pituitary hormone-producing cells from pluripotent stem cells.
-
6.
公开(公告)号:EP4365299A3
公开(公告)日:2024-08-07
申请号:EP24163345.2
申请日:2019-05-16
Applicant: Olives Biotherapeutics Inc.
Inventor: PARK, Woo Jin , YOON, Aeri
IPC: A61K38/18 , A61K39/395 , A61K31/7105 , A61K31/7088 , A61K35/12 , A61K35/28 , A61K35/30 , A61K35/545 , A61K35/76 , A61P27/02 , C07K16/22 , C12N15/86
CPC classification number: A61P27/02 , A61K38/18 , C07K16/22 , A61K35/30 , A61K31/7088 , A61K35/545 , C12N15/86 , C12N2750/1414320130101 , C12N2750/1412320130101
Abstract: The present invention relates to a pharmaceutical composition comprising CCN5 as an active ingredient, for preventing or treating retinal diseases, particularly wet macular degeneration. CCN5 according to the present invention prevents fibrotic changes, caused by TGF-β, EEF, or anti-VEGF drugs, in retinal pigment epithelial cells. In addition, CCNS recuperates the morphological or functional damage, caused by fibrotic changes, of retinal pigment epithelial cells to the level of normal cells. Therefore, the composition comprising CCNS as an active ingredient can be advantageously utilized for preventing or treating retinal diseases.
-
公开(公告)号:EP4402248A1
公开(公告)日:2024-07-24
申请号:EP22870765.9
申请日:2022-09-16
Applicant: Regents of the University of Minnesota
Inventor: O'BRIEN, Timothy D. , LINDBORG, Beth , VEGOE, Amanda , CHAI, Yi Wen , LI, Manci
CPC classification number: A61K35/30 , A61K35/32 , C12N5/0697 , C12N2506/4520130101 , C12N2513/0020130101
-
公开(公告)号:EP3399026B1
公开(公告)日:2024-06-26
申请号:EP18179127.8
申请日:2011-06-14
IPC: C12N5/071 , C12N5/0797 , C12N5/0793 , A61K35/30 , A61K35/33 , A61K35/34 , C12N5/077 , A61K35/39 , C12N5/079 , C12N5/074 , C12N5/073 , C12N15/85
CPC classification number: C12N5/0657 , C12N2501/15520130101 , C12N2501/60220130101 , C12N2501/60320130101 , C12N2501/60420130101 , C12N2501/60620130101 , C12N2506/130720130101 , C12N2510/0020130101 , C12N5/0618 , C12N2501/72720130101 , C12N5/0678 , C12N2501/0120130101 , C12N5/0676 , C12N5/0623
-
公开(公告)号:EP4384188A1
公开(公告)日:2024-06-19
申请号:EP22786670.4
申请日:2022-08-11
Applicant: Sana Biotechnology, Inc.
Inventor: DOWDLE, William , THAM, Eleonore , RAMOS-ZAYAS, Rebeca , SCHREPFER, Sonja
IPC: A61K35/17 , A61K35/30 , A61K35/36 , A61K35/39 , A61K35/44 , A61K35/55 , A61P37/06 , C12N5/079 , C12N5/071 , C12N5/0783 , C12N15/113 , C07K14/705
CPC classification number: A61K35/39 , A61K35/44 , A61K35/55 , A61K35/30 , A61P37/06 , C12N5/0636 , C12N5/0621 , C12N15/1138 , C07K14/70596 , C12N2310/2020170501 , C12N5/0623 , C12N2506/4520130101 , C12N2510/0020130101 , C12N5/0676 , A61K35/34 , A61K35/407 , A61K45/06 , A61K39/4613 , A61K39/464411 , A61K39/4631
-
公开(公告)号:EP4381051A1
公开(公告)日:2024-06-12
申请号:EP22851513.6
申请日:2022-08-03
Applicant: University Health Network
Inventor: FEHLINGS, Michael George , KHAZAEI, Mohammad , AHUJA, Christopher S.
CPC classification number: A61K35/30 , A61P25/28 , A61P25/00 , C07K14/4702 , C12N5/0619 , C12N2506/4520130101 , C12N2501/11520130101 , C12N2501/11920130101 , C12N2501/38520130101
-
-
-
-
-
-
-
-
-