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31.发明公开CYCLOALKYL AND HETEROCYCLOALKYL SUBSTITUTED BENZOTHIOPHENES AS THERAPEUTIC AGENTS 审中-公开环杂环和取代的苯并作为治疗剂
公开(公告)号：EP1636210A1
公开(公告)日：2006-03-22
申请号：EP04734574.9
申请日：2004-05-24
发明人： CONNOLLY, Michael Kevin PFIZER GLOBAL RESEARCH & D , GOGLIOTTI, Rocco Dean PFIZER GLOBAL RES. & DEVELOP , LEE, Helen Tsenwhei PFIZER GLOBAL RES.& DEVELPMNT. , PLUMMER, Mark Stephen PFIZER GLOBAL RES. & DEVELOP , SEXTON, Karen Elaine PFIZER GLOBAL RESEARCH & DEV. , VISNICK, Melean PFIZER GLOBAL RESEARCH & DEVLOPMNT
IPC分类号： C07D409/12 , C07D409/14 , A61K31/41 , A61P11/00
CPC分类号： C07D409/12 , C07D409/14
摘要： The present invention provides benzo[b]thiophenes of Formula (I) wherein R1, R2, R3, and L have any of the values defined therefor in the specification, and pharmaceutically acceptable salts thereof, that are useful as agents in the treatment of diseases and conditions, including inflammatory diseases, cardiovascular diseases, and cancers. Also provided are pharmaceutical compositions comprising one or more compounds of Formula (I).
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32.发明公开FAST DISSOLVING ORALLY CONSUMABLE FILMS CONTAINING SUCRALOSE AS A SWEETENER 审中-公开快速解决口头的可食性膜含三氯蔗糖的甜味剂AS
公开(公告)号：EP1635796A1
公开(公告)日：2006-03-22
申请号：EP04727069.9
申请日：2004-04-13
发明人： KULKARNI, Neema M., c/o Pfizer Global Res.&Develop , KUMAR, Lori D. c/oPfizer Global Res.&Develop. , SORG, Albert F. c/oPfizer Global Res.&Devel.
IPC分类号： A61K9/70
CPC分类号： A61K8/0208 , A61K8/0216 , A61K8/21 , A61K8/34 , A61K8/347 , A61K8/37 , A61K8/416 , A61K8/43 , A61K8/44 , A61K8/4973 , A61K8/60 , A61K8/64 , A61K8/645 , A61K8/65 , A61K8/73 , A61K8/731 , A61K8/732 , A61K8/733 , A61K8/736 , A61K8/8129 , A61K8/8147 , A61K8/8152 , A61K8/8176 , A61K8/86 , A61K8/922 , A61K9/0056 , A61K9/006 , A61K9/2072 , A61K9/7007 , A61K31/00 , A61K31/585 , A61Q11/00
摘要： A consumable film adapted to adhere to and dissolve in the oral cavity of a warm-blooded animal including humans, comprising at least one water soluble polymer, a taste masking effective amount of a sweetener, and a pharmaceutically active agent having a sufficiently unpleasant taste that it is desirably masked by the sweetener.
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公开(公告)号：EP1635788A1
公开(公告)日：2006-03-22
申请号：EP04735617.5
申请日：2004-06-01
CPC分类号： A61K31/401 , A61K9/1611 , A61K9/1623 , A61K9/1652 , A61K9/1676 , A61K9/1688 , A61K9/2018 , A61K9/2054 , A61K31/40
摘要： A dry-granulated pharmaceutical composition comprising atorvastatin or a pharmaceutically acceptable salt thereof, as well as a dry-granulated pharmaceutical composition comprising atorvastatin or a pharmaceutically acceptable salt thereof in combination with at least one other active drug, methods for preparing said compositions, kits for containing such compositions, and a method of treating hypercholesterolemia and/or hyperlipidemia, osteoporosis, benign prostatic hyperplasia (BPH), and Alzheimer's disease using a therapeutically effective amount of the pharmaceutical composition.
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公开(公告)号：EP1628945A1
公开(公告)日：2006-03-01
申请号：EP04731692.2
申请日：2004-05-07
IPC分类号： C07C39/17 , A61K8/18 , A61K31/045
CPC分类号： A61Q19/02 , A61K8/347 , C07C37/16 , C07C39/17 , C07C2601/08
摘要： The present invention is directed to crystalline forms of anhydrous 4-cyclopentyl resorcinol, the Form A and C polymorphs, formulations containing at least one of these crystalline forms and their use to lighten skin.
摘要翻译： 本发明涉及无水4-环戊基间苯二酚的结晶形式，A型和C型多晶型物，含有这些结晶形式中的至少一种的制剂及其减轻皮肤的用途。
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公开(公告)号：EP1614675A2
公开(公告)日：2006-01-11
申请号：EP05108848.2
申请日：2003-03-17
IPC分类号： C07C229/08 , C07C229/28 , A61K31/195 , A61P25/00 , A61P1/00 , C07C229/34 , C07C229/26
CPC分类号： C07C229/08 , A61K31/195 , A61K31/198 , C07C229/28 , C07C229/34 , C07C2601/02 , C07C2601/04 , C07C2601/08 , C07C2601/14 , Y02A50/415
摘要： The invention relates to compounds of the formula II, III and IV, compositions comprising them and their use in the treatment of, inter alia, pain.
摘要翻译： 本发明涉及式II，III和IV的化合物，包含它们的组合物以及它们尤其用于治疗疼痛的用途。
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公开(公告)号：EP1203767B1
公开(公告)日：2006-01-04
申请号：EP02001573.1
申请日：1994-02-08
发明人： Lee, Helen Tsenwhei , O'Brian, Patrick Michael , Picard, Joseph Armand , Purchase, Claude Forsey, Jr. , Roth, Bruce David , Sliskovic, Drago Robert , White, Andrew David
IPC分类号： C07D257/04 , C07D233/54 , C07D231/12 , C07D249/04 , C07D261/08 , C07D271/06 , C07D271/10 , C07D403/12 , C07D401/12 , C07D471/04 , A61K31/41 , A61P9/10 , C07D221/00
CPC分类号： C07D231/12 , C07D233/56 , C07D249/04 , C07D257/04 , C07D261/08 , C07D271/06 , C07D271/10 , C07D277/22 , C07D401/06 , C07D401/12 , C07D401/14 , C07D403/12 , C07D471/04
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公开(公告)号：EP1202699B1
公开(公告)日：2005-11-23
申请号：EP00943950.6
申请日：2000-06-30
IPC分类号： A61J3/07
CPC分类号： A61J3/072
摘要： The invention is concerned with a method of sealing a hardshell capsule having coaxial body parts which overlap when telescopically joined with each other, thereby forming a gap around a circumference of the capsule, comprising the steps of individually applying a sealing liquid including a solvent uniformly to the external edge of the gap of a capsule to be sealed to form a liquid ring around the circumference of the capsule, removing excess sealing liquid from the exterior of the capsule, drying the capsule by applying thermal energy from outside while gently tumbling and conveying the capsule on a spiral path.
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公开(公告)号：EP1594830A1
公开(公告)日：2005-11-16
申请号：EP04706758.2
申请日：2004-01-30
CPC分类号： A61Q19/02 , A61K8/347 , A61K31/05 , C07B2200/13 , C07C39/17
摘要： The present invention is directed to 4-cyclopentyl resorcinol monohydrate, its Form I polymorph, formulations containing at least one of these compounds, and their use to lighten skin.
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公开(公告)号：EP1592661A2
公开(公告)日：2005-11-09
申请号：EP04701059.0
申请日：2004-01-09
发明人： SCHWARZ, Jacob Bradley,Pfizer Global Res. & Dev. , WUSTROW, David Juergen,Pfizer Global Res. & Dev.
IPC分类号： C07D201/00
CPC分类号： C07C229/46 , C07C2601/02 , C07C2601/04 , C07C2601/08 , C07C2601/14 , C07C2601/18 , C07C2602/50
摘要： This invention relates to novel cyclopropyl β-amino acids derivatives of the formula (I) wherein R1 through R4 are defined as in the specification, pharmaceutical compositions containing them and their use for the treatment of various central nervous system and other disorders. The cyclopropyl β-amino acids derivatives of this invention exhibit activity as alpha2delta ligands (α2δ ligands). Such compounds have affinity for the α2δ subunit of a calcium channel.
摘要翻译： 本发明涉及下式的新型环丙基β-氨基酸衍生物：其中R 1至R 4中的定义如说明书中所定义，含有它们的药物组合物及其用于 治疗各种中枢神经系统等疾病。 本发明的环丙基β-氨基酸衍生物表现出作为α2delta配体（α2delta配体）的活性。 这样的化合物对钙通道的α2delta亚基具有亲和力。
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公开(公告)号：EP1580229A1
公开(公告)日：2005-09-28
申请号：EP04290850.9
申请日：2004-03-22
IPC分类号： C08L5/00
CPC分类号： C08L1/02 , A61K9/4816 , C08L1/00 , C08L1/08 , C08L1/10 , C08L1/12 , C08L1/14 , C08L1/16 , C08L1/18 , C08L1/20 , C08L1/22 , C08L1/24 , C08L1/26 , C08L1/28 , C08L1/282 , C08L1/284 , C08L1/286 , C08L1/288 , C08L1/30 , C08L1/32 , C08L3/00 , C08L3/02 , C08L3/04 , C08L3/06 , C08L3/08 , C08L3/10 , C08L3/12 , C08L3/14 , C08L3/16 , C08L3/18 , C08L3/20 , C08L5/00 , C08L5/02 , C08L5/12 , C08L2666/02 , C08L2666/26
摘要： This invention relates to biopolymer-based compositions and biopolymer-based formed bodies such as film, sheet, capsule, casing or coating-film or spray thereof. In another embodiment, the invention relates to a process for producing a biopolymer-based starting material and biopolymer-based formed bodies such as cited above, for the manufacture of pharmaceutical, veterinary, food or cosmetic products.
摘要翻译： 本发明涉及基于生物聚合物的组合物和基于生物聚合物的成形体，例如膜，片，胶囊，壳体或涂膜或喷雾剂。 在另一个实施方案中，本发明涉及生产基于生物聚合物的起始材料和如上引用的生物聚合物基成型体用于制造药物，兽药，食品或化妆品的方法。
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