摘要:
An apparatus and method is disclosed for forming a compacted powder slug (7) coated with a film (8). The powder (6), e.g. of a medicament, is compacted and enrobed to produce compacted powder slugs (7) by preferably mechanically compacting a powder (6) and forming a film (8) of a material, preferably hydroxy propyl methyl cellulose, by vacuum or pressure differential, about the surface of the powder (6) thus compacted.
摘要:
An apparatus and method is disclosed for forming a compacted powder slug (7) coated with a film (1). The powder (6), e.g. of a medicament, is compacted and enrobed to produce compacted powder slugs (7) by preferably mechanically compacting a powder (6) and forming a film (1) of a material, preferably hydroxy propyl methyl cellulose, by vacuum or pressure differential, about the surface of the powder thus compacted.
摘要:
Microcapsules containing an active ingredient, constituted by a core coated with a polymer membrane, characterized in that the active ingredient is incorporated in the polymer coating layer, and in that said layer is applied using microencapsulation techniques (coacervation by means of phase separation). The microcapsules; thus produced have excellent properties of taste masking and prolonged release of the active ingredients.
摘要:
The invention relates to a form of administration comprising a physiologically effective substance (A); one or several optional physiologically acceptable adjuvants (B); a synthetic or natural polymer (C); and an optional natural, semisynthetic, or synthetic wax (D). Said form of administration is provided with a minimum breaking strength of 400 N while releasing the physiologically effective substance (A) at least partly in a delayed manner in physiological conditions.
摘要:
Apparatuses (201) and methods for electrostatically applying a powder material to substrates are described. A plurality of platens (202, 203) are provided, each arranged to hold a plurality of substrates such as solid dosage forms (101, 111). Each platen (202, 203) is driven around an endless path and passes through a loading region (Fig. 3, 4) in which substrates are loaded onto the platens (202, 203), a developing region (Fig. 5, 6) in which the powder material is applied to the substrates, a fusing region (Fig. 7) in which the applied powder material is fused, and an unloading region (Fig. 8) in which substrates are removed from the platens (202, 203).
摘要:
An apparatus and method is disclosed for forming a compacted powder slug (7) coated with a film (1). The powder (6), e.g. of a medicament, is compacted and enrobed to produce compacted powder slugs (7) by preferably mechanically compacting a powder (6) and forming a film (1) of a material, prefer ably hydroxy propyl methyl cellulose, by vacuum or pressure differential, about the surface of the powder thus compacted.
摘要:
Microcapsules containing an active ingredient, constituted by a core coated with a polymer membrane, characterized in that the active ingredient is incorporated in the polymer coating layer, and in that said layer is applied using microencapsulation techniques (coacervation by means of phase separation). The microcapsules; thus produced have excellent properties of taste masking and prolonged release of the active ingredients.