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32.
公开(公告)号:EP4296355A1
公开(公告)日:2023-12-27
申请号:EP22756235.2
申请日:2022-02-16
IPC分类号: C12N5/10 , A61K35/28 , A61K35/35 , A61P3/04 , A61P9/10 , A61P13/12 , A61P29/00 , A61P31/04 , C07K14/475 , C07K14/50 , C12N5/077 , C12N5/0775 , C12N15/90 , C12P21/02 , A01K67/027
摘要: Provided are: a non-human animal or a part of the same in which the function of Mipep gene is totally or partially lost in adipose tissues or the expression level of Mipep gene in adipose tissues is lowered compared to a wild type; and mesenchymal stem cells or adipocytes in which the function of Mipep gene is totally or partially lost or the expression level of Mipep gene is lowered compared to a wild type. Also provided are: a therapeutic or prophylactic drug that comprises the aforesaid mesenchymal stem cells or adipocytes or a culture supernatant thereof; and a method for preparing a mitokine mixture using the aforesaid non-human cells, mesenchymal stem cells or adipocytes.
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公开(公告)号:EP4245361A3
公开(公告)日:2023-11-22
申请号:EP23188581.5
申请日:2016-11-11
IPC分类号: A61L31/18 , A61K35/28 , A61K35/545 , C12N5/0775 , A61L27/38 , A61N5/067 , A61L27/36 , A61P9/00 , A61P25/00 , A61N5/06 , C12N5/0789
摘要: Harvested stem cells are activated by treating them with an amplitude modulated laser beam having a wavelength lying in the range of 405 to 980 nanometers. The frequency of the laser beam is modulated within a range of 8 to 12 MHz. Using the activated stem cells, tissue can be repaired and regenerated by preparing the unactivated stem cells, treating the unactivated stem cells with an amplitude modulated laser beam having a pre-determined frequency for obtaining activated stem cells, administering the activated stem cells into a body containing the tissue, and using a homing beam to guide the activated stem cells within the body to the location of the tissue.
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公开(公告)号:EP3226876B1
公开(公告)日:2023-11-01
申请号:EP15866203.1
申请日:2015-11-30
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35.
公开(公告)号:EP4263806A1
公开(公告)日:2023-10-25
申请号:EP21831056.3
申请日:2021-12-17
申请人: UNIVERSITE DE MONTPELLIER , Centre National de la Recherche Scientifique (CNRS) , Institut National de la Santé et de la Recherche Médicale (INSERM) , Centre Hospitalier Universitaire de Montpellier
IPC分类号: C12N5/0775 , A61K35/28 , A61P9/10
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公开(公告)号:EP4262831A1
公开(公告)日:2023-10-25
申请号:EP21907934.0
申请日:2021-12-17
申请人: Ossium Health, Inc.
发明人: WOODS, Erik, J. , JOHNSTONE, Brian, H. , GU, Dongsheng , SHERRY, Aubrey, Marie , MUSALL, Kelsey, Gwen , SYKES, Megan , KATO, Tomoaki , FU, Jianing
IPC分类号: A61K35/28 , A61K31/706 , A61K35/17 , A61K35/38 , C07K16/28
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37.
公开(公告)号:EP3669884B1
公开(公告)日:2023-10-18
申请号:EP18845495.3
申请日:2018-08-16
发明人: LEW, He Len , PARK, Mi Ra , KIM, Gi Jin
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公开(公告)号:EP4247396A1
公开(公告)日:2023-09-27
申请号:EP21827718.4
申请日:2021-11-19
IPC分类号: A61K35/28 , A61K31/713 , A61K35/761 , A61P19/02 , C12N15/00
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