公开(公告)号：EP3289972B1

公开(公告)日：2023-09-06

申请号：EP17196217.8

申请日：2009-07-30

发明人： MAHADEVAN-JANSEN, Anita ,  WHITE, Lisa ,  PHAY, John ,  PARAS, Constantine, A. ,  KANTER BARTZ, Elizabeth ,  KELLER, Matthew, D. ,  GASPARINO, Nicole ,  WHISENANT, Jennifer, Gray ,  PENCE, Isaac J.

IPC分类号： A61B5/05 ,  A61B5/00 ,  G01N21/65

公开(公告)号：EP3677902B1

公开(公告)日：2023-08-30

申请号：EP19198401.2

申请日：2019-09-19

发明人： KIM, Unjeong ,  PARK, Yeonsang ,  ROH, Younggeun

IPC分类号： G01N21/65 ,  G02B1/00 ,  G01J3/44

公开(公告)号：EP3467480B1

公开(公告)日：2023-08-23

申请号：EP17806634.6

申请日：2017-05-29

发明人： FUKUTAKE Naoki

IPC分类号： G01N21/64 ,  G01N21/27 ,  G01N21/65 ,  G02B21/00 ,  G01N21/45 ,  G01N21/47 ,  G02B5/30

公开(公告)号：EP4220140A1

公开(公告)日：2023-08-02

申请号：EP23175587.7

申请日：2020-07-22

申请人： Agilent Technologies LDA UK Limited

发明人： TELLA, Richard ,  PETERS, Craig

IPC分类号： G01N21/65 ,  G01N33/15 ,  G01N21/13 ,  G01N21/95

摘要： There are disclosed methods and apparatus for automatic analysis of pharmaceutical dosage forms. In some aspects a dosage form may be grasped by a gripper which is used to bring the dosage form to a test location and to present the dosage form in a plurality of different alignments between delivery and collection optics. Probe light scattered through the dosage form is collected during each alignment. The collected probe light for the plurality of alignments is then used for Raman spectral analysis of the dosage form. In other aspects a rotation stage is used to rotate a dosage form on the stage to a preferred alignment before being grasped by a gripper. The gripper is then used to carry the dosage form to the test location for optical analysis.

公开(公告)号：EP3548179B1

公开(公告)日：2023-08-02

申请号：EP17816604.7

申请日：2017-12-04

发明人： STADTHAGEN, Torsten ,  FREMMER, Markus

IPC分类号： B01L3/00 ,  G01N21/65 ,  A61B10/00 ,  G01N1/00 ,  G01N1/02

公开(公告)号：EP4214491A1

公开(公告)日：2023-07-26

申请号：EP20780109.3

申请日：2020-09-16

申请人： Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V.

发明人： FATTAHI, Hanieh

IPC分类号： G01N21/63 ,  G01N21/65

公开(公告)号：EP4206655A1

公开(公告)日：2023-07-05

申请号：EP21217931.1

申请日：2021-12-28

申请人： Serstech AB

发明人： Szybek, Katja

IPC分类号： G01N21/65 ,  G01N21/27 ,  G01N21/47

摘要： The present inventive concept relates to a method for compensating a first signal based on a second signal, and to a system for Raman spectroscopy. The system (100) for Raman spectroscopy comprising: a dichroic mirror (113) configured to reflect a first portion (104a) of light having wavelengths within a first wavelength interval and to transmit a second portion (104b) of light having wavelengths within the first wavelength interval, and to transmit light having wavelengths within a second wavelength interval; a light source (110) configured to illuminate the dichroic mirror (113) with light having wavelengths within the first wavelength interval; a spectrometer (120) comprising: a light sensor (126), a dispersive element (124), a first entrance slit (121a), and a second entrance slit (121b), wherein the spectrometer (120) is configured to direct, via the dispersive element (124), light entering through the first entrance slit (121a) to a first portion (126a) of the light sensor (126), and to direct, via the dispersive element (124), light entering through the second entrance slit (121b) to a second portion (126b) of the light sensor (126); wherein the dichroic mirror (113) is configured to reflect light of the first portion (104a) to illuminate a sample, and to transmit light of the second portion through the dichroic mirror (113); wherein the dichroic mirror (113) is further configured to transmit light scattered by the sample, wherein the light scattered by the sample has wavelengths within the second wavelength interval; wherein the spectrometer (120) is arranged to receive, at the first entrance slit (121a), light scattered by the sample, and to receive, at the second entrance slit (121b), light of the second portion transmitted through the dichroic mirror (113); the system (100) further comprising: circuitry (160) configured to execute: a determination function (172) configured to determine a first signal associated with the first portion (126a) of the light sensor (126), and a second signal associated with the second portion (126b) of the light sensor (126); and wherein the first signal includes a first information pertaining to a Raman spectrum of the sample and the second signal includes a second information pertaining to wavelengths of light emitted by the light source (110), thereby allowing the first information to be compensated by means of the second information.

公开(公告)号：EP4206654A1

公开(公告)日：2023-07-05

申请号：EP21217930.3

申请日：2021-12-28

申请人： Serstech AB

发明人： Szybek, Katja

IPC分类号： G01N21/65 ,  G01N21/27

摘要： The present inventive concept relates to a method and a system for Raman spectroscopy. The system (100) for Raman spectroscopy comprising: a dichroic mirror (113) configured to reflect a first portion (104a) of light having wavelengths within a first wavelength interval and to transmit a second portion (104b) of light having wavelengths within the first wavelength interval, and to transmit light having wavelengths within a second wavelength interval; and a light source (110) configured to illuminate the dichroic mirror (113) with light having wavelengths within the first wavelength interval; wherein the dichroic mirror (113) is configured to reflect light of the first portion (104a) to illuminate a sample (102) and to transmit light of the second portion (104b) to illuminate a reference sample (202), and wherein the dichroic mirror (113) is further configured to transmit light scattered (106) by the sample (102) having wavelengths within the second wavelength interval; the system (100) further comprising: a spectrometer (120) comprising an entrance slit (121) configured to receive light (106) scattered by the sample (102) and light (206) scattered by the reference sample (202); and circuitry (160) configured to execute: a determination function (172) configured to determine, using the spectrometer (120), a signal comprising a first information pertaining to a Raman spectrum of the sample (102) and a second information pertaining to a Raman spectrum of the reference sample (202), thereby allowing the first information to be compensated by means of the second information.

公开(公告)号：EP4206626A1

公开(公告)日：2023-07-05

申请号：EP21217935.2

申请日：2021-12-28

申请人： Serstech AB

发明人： Billsten, Peter

IPC分类号： G01J3/02 ,  G01N21/65

摘要： The present invention relates to a handheld Raman spectroscopy device (10) comprising: a light source (11), a spectrometer (12), a capillary arrangement (21), and a focusing arrangement (13). The light source (11) is configured to emit light to the capillary arrangement (21) via the focusing arrangement (13), wherein the focusing arrangement (13) is configured to focus light (35) emitted from the light source (11) to a measurement location (22) in a capillary vessel (23) of the capillary arrangement (21).

公开(公告)号：EP4202418A1

公开(公告)日：2023-06-28

申请号：EP23156260.4

申请日：2014-02-07

申请人： Hamamatsu Photonics K.K.

发明人： ITO, Masashi ,  SHIBAYAMA, Katsumi ,  OFUJI, Kazuto ,  OYAMA, Hiroki ,  MARUYAMA, Yoshihiro

IPC分类号： G01N21/65 ,  G01N21/03 ,  B01L9/00 ,  G02B21/34

摘要： A SERS unit 1A comprises a SERS element 2 having a substrate 21 and an optical function part 20 formed on the substrate 21, the optical function part 20 for generating surface-enhanced Raman scattering; a transportation board 3 supporting the SERS element 2 during transportation, the SERS element 2 being removed from the transportation board 3 upon measurement; and a holding part 4 having a pinching part 41 pinching the SERS element 2 in cooperation with the transportation board 3, and detachably holding the SERS element 2 in the transportation board 3.