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公开(公告)号：EP2341960A1
公开(公告)日：2011-07-13
申请号：EP09778024.1
申请日：2009-08-21
IPC分类号： A61M5/30
CPC分类号： A61M5/30 , A61M5/2033 , A61M2005/2013 , A61M2005/2073 , A61M2005/3106
摘要： The invention relates to a needle-less, disposable injector comprising a housing (10), which has at least one compression bar, a cylinder-piston unit (100), a plunger-actuating ram (60), a trigger unit (80) and a spring energy reservoir (50), wherein the trigger unit locks the pretensioned spring energy reservoir by means of the compression bar. During triggering, the compression bar slides along at least one trigger element (82) of the trigger unit and, after triggering the trigger unit, the spring energy reservoir displaces the compression bar by means of the plunger-actuating ram and actuates the cylinder-piston unit. When loaded by the pretensioned spring energy reservoir, the pairing formed by the mutually facing inner wall of the trigger element and the contact surface of the compression bar has at least in areas a higher sliding friction coefficient than the pairing formed by the mutually facing collar surface of the plunger-actuating ram and the support surface of the compression bar. The present invention provides a disposable injector where the required minimum contact-pressure force is ensured during use thereof.
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公开(公告)号：EP2064127A1
公开(公告)日：2009-06-03
申请号：EP07801673.0
申请日：2007-08-16
CPC分类号： A61J1/065 , A61J1/062 , A61J1/1468 , B65D2251/0093
摘要： The invention relates to a closing system for containers for storing or administering liquid, pasty or powdery materials, consisting of a cap (81, 82) provided with a through-hole (85) and a closing element (60), the cap holding the closing element on the container (10, 50) in a non-positive or positive manner, in the region of the opening (12) to be closed, by means of a rear grip (37) on the container. To this end, the front surface (21) surrounding the container opening and on which the closing element is arranged comprises a recess (24, 25). The closing element is a virus-tight, bacteria-tight and spore-tight film which lies on the front surface and at least partially over the recess. An elastomer or adhesive ring (71, 72) filling the recess is arranged between the closing element and the recess for the positioning of the cap. The invention provides a closing system for containers which enables the container to be closed in a virus-tight, bacteria-tight, spore-tight and lastingly secure manner.
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公开(公告)号：EP2029102A1
公开(公告)日：2009-03-04
申请号：EP07725822.6
申请日：2007-06-04
IPC分类号： A61K9/00 , A61K9/20 , A61K9/70 , A61K31/19 , A61K31/196 , A61K31/515 , A61K31/5513
CPC分类号： A61K9/006 , A61K9/0031 , A61K9/0034 , A61K9/0043 , A61K9/0056 , A61K31/19 , A61K31/196 , A61K31/485 , A61K31/515 , A61K31/5513 , A61K45/06 , A61K2300/00
摘要： Illnesses or injuries are usually accompanied by pain, with pain itself now being regarded as an illness and increasingly occurring as an independent symptom. The present invention relates to wafer-like presentations for pain therapy, based on hydrophilic polymers, which rapidly dissolve or disintegrate in a watery environment and which release active agent combinations when placed into a body orifice or body cavity, and which are preferably orally administered, with the presentation containing an active agent combination consisting of an opioid and a second substance, wherein the second active agent is a non-steroidal anti-rheumatic (NSAR) or an antidepressant.
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公开(公告)号：EP1208140A1
公开(公告)日：2002-05-29
申请号：EP00960450.5
申请日：2000-08-14
CPC分类号： B01J2/06 , A61J3/00 , A61K9/1652 , A61K9/4866
摘要： This invention relates to porous, rapidly decomposing, contain an active ingredient and pellets which are based on chitosan or an alkaline chitosan derivative manufactured by a dropping method in which an aqueous solution or dispersion of chitosan or an alkaline chitosan derivative, one or more active ingredients, optionally other additives and acid is added drop-wise into a cooling liquid with a maximum temperature of -5 °C and allowed to congeal drop by drop. The congealed droplets or pellets are then isolated and dried. The invention also relates to the use of said pellets in the manufacture of a medicament or a diagnostic product.
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45.发明授权
公开(公告)号：EP0961611B1
公开(公告)日：2002-03-27
申请号：EP98906865.5
申请日：1998-01-09
CPC分类号： A61K9/4808 , A61D7/00 , A61K9/0065 , A61K9/009 , A61M31/002
摘要： The invention concerns a device for the controlled release of active substances in the gastro-intestinal tract with a retarded passage through the pylorus, the device comprising a component which can expand on contact with gastric juice and is surrounded by a polymer casing which is permeable to gastric juice and active substances. The device comprises at least one active substance in the form of a multi-particle preparation which releases the active substance into the gastric juice in retarded manner. The release of active substance from a device according to the invention can be controlled better than conventional medicaments with a retarded passage through the pylorus. Similarly, the device can easily be rolled or folded and inserted in capsules without difficulty.
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46.发明公开PHARMAZEUTISCHE ZUSAMMENSETZUNG, ENTHALTEND DESOXYPEGANIN ZUR BEHANDLUNG DES ALKOHOLISMUS 有权药物组合物含desoxypeganine用于治疗酒精中毒
公开(公告)号：EP1154776A1
公开(公告)日：2001-11-21
申请号：EP00907514.4
申请日：2000-02-08
IPC分类号： A61K31/519 , A61P25/32
CPC分类号： A61K31/505 , Y10S514/81 , Y10S514/811
摘要： Desoxypeganine and its pharmaceutically acceptable acid addition salts can be used in the treatment of alcoholism. Said substances are administered preferably in a continuos and controlled manner. The pharmaceutical administration form enables controlled release, e.g. for oral, transdermal or another route of parenteral administration.
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47.发明公开PHARMAZEUTISCHE ZUSAMMENSETZUNG ENTHALTEND DESOXYPEGANIN ZUR BEHANDLUNG DER DROGENABHÄNGIGKEIT 有权药物组合物含desoxypeganine药物成瘾的治疗
公开(公告)号：EP1152763A2
公开(公告)日：2001-11-14
申请号：EP00910649.3
申请日：2000-02-08
IPC分类号： A61K31/519 , A61P25/30
CPC分类号： A61K31/519
摘要： Desoxypeganine and its pharmaceutically acceptable acid addition salts can be used in the treatment of drug addiction or drug dependence. Said substances are administered preferably in a continuos and controlled manner. The pharmaceutical administration form enables controlled release, e.g. for oral, transdermal or another route of parenteral administration.
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48.发明公开VERWENDUNG VON DESOXYPEGANIN ZUR BEHANDLUNG VON ALZHEIMERISCHER DEMENZ 有权使用deoxypeganine对治疗痴呆ALZHEIMERISCHER
公开(公告)号：EP1152762A1
公开(公告)日：2001-11-14
申请号：EP00907513.6
申请日：2000-02-08
IPC分类号： A61K31/519 , A61P25/28
CPC分类号： A61K31/519 , Y10S514/906
摘要： The invention relates to a device and method for the treatment of Alzheimer's dementia with desoxypeganine and/or a pharmaceutically acceptable acid addition salt of desoxypeganine.
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49.发明授权
公开(公告)号：EP0790764B1
公开(公告)日：2000-09-20
申请号：EP95936552.9
申请日：1995-10-26
IPC分类号： A01G7/06
CPC分类号： C05G3/0052 , A01G7/06 , A01N25/34
摘要： Bei einer implantierbaren Vorrichtung zur Abgabe von Wirkstoffen an Pflanzen, wobei diese ein von Poren durchsetzter keramischer Formkörper ist, in dem der Wirkstoff in offenen Poren verteilt ist, ist das Porenvolumen zum Zeitpunkt der Implantation so bemessen, dass es die gesamte abzugebende Wirkstoffmenge enthält, wobei die Art der Gesamtporosität, deren Volumen, Grösse und Streuung sowie Verteilung der Poren in vorgegebenen Grenzen festlegbar ist.
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