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46 条记录 (耗时 0.017 秒)

    SYSTEM AND METHOD FOR PROVIDING CELL SPECIFIC LASER THERAPY OF ATHEROSCLEROTIC PLAQUES BY TARGETING LIGHT ABSORBERS IN MACROPHAGES
    41.
    发明公开
    SYSTEM AND METHOD FOR PROVIDING CELL SPECIFIC LASER THERAPY OF ATHEROSCLEROTIC PLAQUES BY TARGETING LIGHT ABSORBERS IN MACROPHAGES 审中-公开
    SYSTEM AND METHOD FOR PROVIDING IN粥样硬化斑块小区特定激光治疗BY物质在巨噬细胞靶向光吸收

    公开(公告)号：EP1991313A2

    公开(公告)日：2008-11-19

    申请号：EP07757707.0

    申请日：2007-03-01

    申请人： The General Hospital Corporation

    发明人： NADKARNI, Seemantini, K. ,  TEARNEY, Guillermo, J. ,  BOUMA, Brett, E. ,  VAKOC, Benjamin, J. ,  ANDERSON, Richard, Rox

    IPC分类号： A61N5/06

    CPC分类号： A61B18/245 ,  A61N5/0601 ,  A61N5/062

    摘要： An apparatus and method according to the present invention can be provided, e.g., for a cell specific laser therapy of atherosclerotic plaques, particularly to systems and methods for targeting endogenous light absorbers present within plaque macrophages and exogenous nanoparticle targeting. In one exemplary embodiment, an electro-magnetic radiation can be forwarded to an anatomical structure. The electro-magnetic radiation may have at least one property configured to (a) modify at least one characteristic of at least one first cell, and (b) minimize any modification of and/or modify at least one characteristic of at least second cell. The first and second cells may be different from one another, the characteristics of the first and second cells can be different from one another, and the first cell and/or the second cell may have at least one macrophage feature, and the characteristic of the at least one first cell and/or the at least one second cell can be temperature. According to still another exemplary embodiment, a location associated with the first cell and the second cell can be determined. For example, the electro-magnetic radiation can be forwarded in a vicinity of the location.

    METHOD AND APPARATUS FOR IMAGING OF VESSEL SEGMENTS
    44.
    发明公开
    METHOD AND APPARATUS FOR IMAGING OF VESSEL SEGMENTS 有权
    与流体输送装置和一拉回Vorrichntung成像装置

    公开(公告)号：EP1793731A1

    公开(公告)日：2007-06-13

    申请号：EP05792862.4

    申请日：2005-08-24

    申请人： THE GENERAL HOSPITAL CORPORATION

    发明人： TEARNEY, Guillermo, J. ,  SHISHKOV, Milen ,  BOUMA, Brett, E.

    IPC分类号： A61B5/00

    CPC分类号： A61B5/6852 ,  A61B5/0062 ,  A61B5/0066 ,  A61B5/0084 ,  A61B5/02007

    摘要： An apparatus, method and software arrangement for imaging a surface of a structure that is in contact with an opaque fluid is provided. The apparatus includes an article of manufacture (208) (e.g., a housing), a fluid delivery arrangement and an imaging arrangement (204). The housing includes an aperture (221) formed in the article of manufacture. The fluid delivery arrangement is configured to deliver a volume of substantially transparent fluid to the aperture formed in the housing. The imaging arrangement is configured to image the surface of the structure using an imaging modality after the volume of the transparent fluid is delivered to the aperture, wherein the imaging arrangement and/or the article of manufacture is translated (BY A Pullback device -215) along the surface of the structure while imaging the surface of the structure.

    PROCESS, SYSTEM AND SOFTWARE ARRANGEMENT FOR MEASURING A MECHANICAL STRAIN AND ELASTIC PROPERTIES OF A SAMPLE
    45.
    发明公开
    PROCESS, SYSTEM AND SOFTWARE ARRANGEMENT FOR MEASURING A MECHANICAL STRAIN AND ELASTIC PROPERTIES OF A SAMPLE 有权
    方法，系统和软件的安排确定弹性模

    公开(公告)号：EP1793730A2

    公开(公告)日：2007-06-13

    申请号：EP05791226.3

    申请日：2005-08-24

    申请人： THE GENERAL HOSPITAL CORPORATION

    发明人： BOUMA, Brett, E. ,  CHAN, Raymond, C. ,  TEARNEY, Guillermo, J.

    IPC分类号： A61B5/00

    CPC分类号： A61B5/0066 ,  A61B5/0059 ,  A61B5/02007

    摘要： A system, process and software arrangement are provided to determining data associated with at least one structural change of tissue. In particular, a first optical coherence tomography ('OCT”) signal which contains first information regarding the tissue at a first stress level, and a second OCT signal which contains second information regarding the tissue at a second stress level are received. The first and second information are compared to produce comparison information. The data associated with the at least one structural change is determined as a function of the comparison information and further information associated with (i) at least one known characteristics of the tissue and/or (ii) characteristics of an OCT system. Further, at least one optical coherence tomography ('OCT”) signal which contains information regarding the tissue can be received, and the modulus of the tissue may be determined as a function of the received at least one OCT signal.