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41.发明公开Esculetin derivatives and pharmaceutical composition 失效Esculetin Derivate und pharmazeutische Zusammenstellung。
公开(公告)号：EP0614896A1
公开(公告)日：1994-09-14
申请号：EP94103036.3
申请日：1994-03-01
IPC分类号： C07D311/00 , C07D311/16 , A61K31/37
CPC分类号： A61K31/37 , C07D311/16 , Y10S514/825
摘要： A pharmaceutical composition comprising a compound of the general formula (I):
wherein R¹ and R² are, independently, a hydrogen atom, a saturated or unsaturated aliphatic acyl having 2 to 25 carbon atoms or benzoyl group and R³ is a hydrogen atom or alkyl group, and a pharmaceutically acceptable carrier is disclosed. Further, a novel compound of the general formula (I) wherein R¹ and R² are, independently, a hydrogen atom, pivaloyl, capryloyl, lauroyl, palmitoyl, stearoyl, linoleoyl, docosahexaenoyl, or benzoyl group, and R³ is a hydrogen atom or methyl group, is also disclosed.摘要翻译： 一种药物组合物，其包含通式（I）的化合物：其中R 1和R 2独立地为氢原子，具有2至25个碳原子的饱和或不饱和脂族酰基或苯甲酰基 并且R 3是氢原子或烷基，并且公开了药学上可接受的载体。 此外，通式（I）的新化合物，其中R 1和R 2独立地为氢原子，新戊酰基，辛酰基，月桂酰基，棕榈酰基，硬脂酰基，亚油酰基，二十二碳六烯酰基或苯甲酰基，R <3>是氢原子或甲基，也公开。
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42.发明公开Activated carbon as antinephrotic syndrome agent 失效Aktivkohlenstoff als Mittel gegen nephrotisches Syndrom。
公开(公告)号：EP0595715A1
公开(公告)日：1994-05-04
申请号：EP93402632.9
申请日：1993-10-27
IPC分类号： A61K33/44
CPC分类号： A61K33/44
摘要： The present invention provides an antinephrotic syndrome agent containing a spherical carbon as an active ingredient in an amount effective for treating nephrotic syndrome. The agent is orally administered to patients and , unlike conventional steroid medicines, has no side effects. Further, the present invention provides a method of treating nephrotic syndrome including the step of administering an effective amount of spherical carbon to a patient.
摘要翻译： 本发明提供一种含有球形碳作为活性成分的抗肾综合征剂，其量为治疗肾病综合征的有效量。 该药物经口服给予患者，与常规类固醇药物不同，其无副作用。 此外，本发明提供了治疗肾病综合征的方法，包括向患者施用有效量的球形碳的步骤。
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43.发明公开Use of 24,25-dihydroxyvitamin D3 for the manufacture of a medicament for the treatment of rickets 失效使用24,25-二D3的用于制备药物的佝偻病的治疗。
公开(公告)号：EP0575974A1
公开(公告)日：1993-12-29
申请号：EP93110006.9
申请日：1993-06-23
发明人： Seino, Yoshiki , Tanaka, Hiroyuki , Nagai, Yumiko
IPC分类号： A61K31/59
CPC分类号： A61K31/59
摘要： A pharmaceutical composition containing 24,25-dihydroxycholecalciferol is provided. The active ingredient used in the present invention is an intrinsic and safe substance, and so does not exhibit hypercalcemia which is the side effect induced by conventional antirachitic agents, and is effective for the treatment of rickets, particularly vitamin D resistant rickets.
摘要翻译： 提供了一种含有24,25-二羟的药物组合物。 在本发明中使用的活性成分是本征和安全的物质，因此不表现出高钙血症的所有其是由常规的抗佝偻病剂引起的副作用，并有效用于治疗佝偻病的，特别是抗维生素D佝偻病。
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公开(公告)号：EP0384391B1
公开(公告)日：1993-11-03
申请号：EP90103234.2
申请日：1990-02-20
发明人： Taguchi, Takashi , Ouchi, Akio , Uchida, Mitsunobu
IPC分类号： B65D85/672
CPC分类号： B65D83/0882 , B65D83/0841 , B65D85/672 , B65H35/0006 , B65H2701/1752 , Y10T225/222 , Y10T225/248
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45.发明公开
公开(公告)号：EP0526216A2
公开(公告)日：1993-02-03
申请号：EP92306971.0
申请日：1992-07-30
发明人： Wakamori, Hideki , Suzuki, Fujio , Horie, Katsuo
IPC分类号： C08F214/22
CPC分类号： C08F214/22
摘要： A method of manufacturing a vinylidene fluoride polymer wherein a vinylidene fluoride monomer and 1 to 5 wt.%, with respect to the total weight of the monomers, of hexafluoropropylene and/or tetrafluoroethylene comonomers are suspension-polymerized in an aqueous medium in the presence of an oil-soluble polymerization initiator, wherein:
the logarithmic viscosity [η₁] of the polymer is from 1.3 to 1.9 dl/g from the start of the polymerization until the polymerization conversion rate of the vinylidene fluoride monomer is from 10 to 50%; and
when the polymerization conversion rate is from 10 to 50%, a chain transfer agent is added to the polymerization system such that the logarithmic viscosity [η₂] of the polymer finally obtained is from 0.9 to 1.3 dl/g and also from 0.3 to 0.7 dl/g lower than [η₁].摘要翻译： 一种偏二氟乙烯聚合物的制造方法，其中相对于单体的总重量，1,1-二氟乙烯单体和1至5重量％的六氟丙烯和/或四氟乙烯共聚单体在含水介质中的存在下悬浮聚合， 油溶性聚合引发剂，其中：从聚合开始直到聚合转化率为10〜50％，聚合物的对数粘度[η]为1.3〜1.9dl / g。 当聚合转化率为10〜50％时，向聚合体系中添加链转移剂，使得最终获得的聚合物的对数粘度η为0.9〜1.3dl / g，也为0.3〜 比dl降低0.7dl / g。
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公开(公告)号：EP0456157A1
公开(公告)日：1991-11-13
申请号：EP91107313.8
申请日：1991-05-06
IPC分类号： C07C43/313 , C07C317/16 , C07D319/06 , C07C41/56
CPC分类号： C07C41/56 , C07D317/16 , C07D319/06 , C07C43/313
摘要： A process of producing a high-pure acyclic or cyclic chloroacetal with a good yield by a simple step of reacting a monochloroacetaldehyde trimer or a monochloacetaldehyde monomer obtained by heating the trimer in the existence of an acid catalyst and a monohydric or dihydric alcohol having from 1 to 5 carbon atoms in the existence of an acid catalyst or a dehydrating agent.
摘要翻译： 通过简单的步骤，通过在存在酸催化剂的情况下加热三聚物获得的单氯乙醛三聚物或单氯乙醛单体与一元醇或二元醇反应的简单步骤制备具有良好产率的高纯无环或环状氯缩醛的方法，该方法具有1 至5个碳原子存在酸催化剂或脱水剂。
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47.发明公开
公开(公告)号：EP0436207A1
公开(公告)日：1991-07-10
申请号：EP90125215.5
申请日：1990-12-21
发明人： Sekita, Takuo , Abe, Takashi
IPC分类号： G01F23/28
CPC分类号： B29C47/883 , B29C47/0009 , B29C47/0026 , B29C47/8835 , B29C47/8895 , B29C47/92 , B29C2947/92019 , B29C2947/92161 , B29C2947/92314 , B29C2947/92333 , B29C2947/9238 , G01F23/2961 , G01F23/2962 , G01N2291/02836
摘要： A detection method of a liquid level (11) supplies fluid between a moving cylindrical body (26) such as a parison in a film manufacturing process and an ultrasonic transmitter (9) and receiver (10) or an ultrasonic transmitter-receiver opposite to an outer surface of the cylindrical body to keep acoustic contact between an ultrasonic vibration member and the cylindrical body through the fluid. A level of liquid in the cylindrical body is measured on the basis of whether ultrasonic propagating in the fluid and the liquid in the cylindrical body can be received with a predetermined signal level or not. Since the ultrasonic vibration member is brought into contact with the cylindrical body through the fluid, the contact state therebetween is kept good, and wear, flaw, deformation, frictional heat or the like is not given to the cylindrical body. Further, even if the surface of the cylindrical body is rugged, good contact can be kept. Preferably the fluid is flowing water.
摘要翻译： 液面（11）的检测方法提供流体移动圆筒体（26）之间：如在薄膜制造过程中的型坯和超声波发射器（9）和接收器（10）或到超声波发射器 - 接收器相反在 筒状体的外表面以保持声之间的超声波振动元件和圆筒体通过流体接触。 的液体在筒状体A水平被测量的无论是在流体和在所述圆柱形本体的液体超声传播可以与预定的信号电平或不被接收的基础上。 由于超声波振动部件通过流体接触与筒体，有之间的接触状态被保持良好，磨损，缺陷，变形，摩擦热等未给定于圆筒体。 此外，即使筒状体的表面是凹凸不平，良好的接触可以保持。 优选地，流体是流动的水。
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公开(公告)号：EP0286257A3
公开(公告)日：1991-04-17
申请号：EP88302374.9
申请日：1988-03-18
CPC分类号： C08G75/029 , C08G75/0245 , C08K5/54 , C08L81/02
摘要： A modified polyphenylene sulfide resin is produced by the steps of mixing a polyphenylene sulfide resin with at least one silane compound selected from the group consisting of vinylalkoxysilanes, epoxyalkoxysilanes, aminoalkoxysilanes and mercaptoalkoxysilanes and kneading the mixture at a temperature which is higher by 5 to 100°c than the melting point of the polyphenylene sulfide resin for at least 30 seconds. It has an increased melt viscosity.
摘要翻译： 通过将聚苯硫醚树脂与选自乙烯基烷氧基硅烷，环氧烷氧基硅烷，氨基烷氧基硅烷和巯基烷氧基硅烷的至少一种硅烷化合物混合并在高于5〜100℃的温度下捏合该混合物的步骤来制备改性聚苯硫醚树脂。 c比聚苯硫醚树脂的熔点至少30秒。 它具有增加的熔体粘度。
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公开(公告)号：EP0384391A3
公开(公告)日：1991-02-06
申请号：EP90103234.2
申请日：1990-02-20
发明人： Taguchi, Takashi , Ouchi, Akio , Uchida, Mitsunobu
IPC分类号： B65D85/672
CPC分类号： B65D83/0882 , B65D83/0841 , B65D85/672 , B65H35/0006 , B65H2701/1752 , Y10T225/222 , Y10T225/248
摘要： A dispensing carton (1) containing film (8) wound cylindrically includes an adhesive retaining device (10) which retains the leading edge of the film (8) left after the film (8) pulled out from a carton box has been cut by a cutter (7). The retaining device (10) includes a base member (12), a sticking layer (11) mounted on one surface of the base member (12) to fix the base member (12) on the surface of the front panel (6) and an adhesive layer (13) mounted on the other surface of the base member (12). The adhesive layer (13) is formed of grafted copolymer obtained by graft-polymerizing vinyl chloride monomer with copolymer of ethylene and vinylacetate. Preferably, the adhesive layer (13) is formed of grafted copolymer obtained by graft-polymerizing vinyl chloride monomer having weight ratio of 80-20 with copolymer of ethylene and vinylacetate having weight ratio of 20-80 in which the weight ratio of ethylene and vinylacetate is 20-70 to 80-30. Further, the surface of the adhesive layer (13) is partially covered by a resin layer to reduce the surface area of the adhesive layer (14a, 14b) for retaining the film (8).
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公开(公告)号：EP0368613A3
公开(公告)日：1990-12-05
申请号：EP89311506.3
申请日：1989-11-07
IPC分类号： C07D323/06
CPC分类号： C07D323/06 , C07C45/55 , C07C47/14
摘要： A method for preparing a monochloroacetaldehyde trimer in a high yield is here disclosed which comprises the steps of dissolving, in an organic solvent, a solution containing monochloroacetaldehyde as the main component, and then trimerizing monochloroacetaldehyde in the presence of sulfuric acid. The thus prepared monochloroacetaldehyde trimer can be heated at 120°C under atmosphetic pressure to obtain pure monochloroacetaldehyde.
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