公开(公告)号：EP2526922B1

公开(公告)日：2018-10-03

申请号：EP10843875.5

申请日：2010-01-22

Applicant: Dai-Ichi Kogyo Seiyaku Co., Ltd.

Inventor： ISOGAI Akira ,  SUMI Hideyuki ,  GOI Yousuke

IPC: A61K8/73 ,  A61K8/02 ,  C08B15/02 ,  A61Q19/00 ,  A61K8/04

CPC classification number: A61K8/731 ,  A01N25/04 ,  A01N37/40 ,  A61K8/027 ,  A61K8/042 ,  A61K8/046 ,  A61K8/19 ,  A61K8/29 ,  A61K8/31 ,  A61K8/34 ,  A61K8/345 ,  A61K8/37 ,  A61K8/73 ,  A61K8/86 ,  A61K8/891 ,  A61K8/92 ,  A61K8/922 ,  A61K47/38 ,  A61K2800/10 ,  A61K2800/413 ,  A61K2800/48 ,  A61K2800/54 ,  A61Q13/00 ,  A61Q15/00 ,  A61Q19/00 ,  A61Q19/007 ,  A61Q19/10 ,  C08B15/02

Abstract: A viscous composition of the present invention comprises specific cellulose fibers (A), (A') and (A") and the specific cellulose fibers (A), (A') and (A") are used with appropriate selection according to uses of a cosmetic composition, a gel-like composition and a spray composition. Therefore, in case where the composition is used as the cosmetic composition, a cosmetic composition which is excellent in shape retention ability and dispersion stability and excellent in water tolerance to satisfy the properties and the performance which is necessary for cosmetics is obtained. Additionally, in case where the composition is used as a gel-like composition, gel-state can be kept without separation or water release. Furthermore, in case where the composition is used as a spray composition, since it is possible to time-dependently keep stable gel state even if functional additives such as electrolytes, ionic substances, etc. are contained, it is possible to mix various functional additives which is necessary for the use without any problem.

公开(公告)号：EP2328589B1

公开(公告)日：2018-09-19

申请号：EP09781641.7

申请日：2009-08-07

Applicant: ITF Research Pharma, S.L.U

Inventor： ACEBRÓN FERNÁNDEZ, ÁIvaro ,  BLANCO LOUSAME, Dolores ,  MOSCOSO DEL PRADO, Jaime ,  NIETO MAGRO, Concepción

IPC: A61K31/566 ,  A61K9/52 ,  A61P15/02 ,  A61K9/00

CPC classification number: A61K31/566 ,  A61K9/0034 ,  A61K47/32 ,  A61K47/38

Abstract: The present invention relates to the use of estriol in the preparation of a pharmaceutical formulation for vaginal administration with the capacity to self-limit the absorption of estriol, for the prevention and/or the treatment of urogenital atrophy in women, said women having a high probability of developing an estrogen-dependent tumor or suffering or having suffered from an estrogen-dependent tumor.

公开(公告)号：EP3368515A1

公开(公告)日：2018-09-05

申请号：EP16791511.5

申请日：2016-10-27

Applicant: Inception 3, Inc.

Inventor： SEIDERS, Thomas, Jon ,  LEE, Catherine, Yuling ,  LI, Yiwei

IPC: C07D223/18 ,  A61K31/55

CPC classification number: C07D223/20 ,  A61K9/0046 ,  A61K47/02 ,  A61K47/10 ,  A61K47/32 ,  A61K47/34 ,  A61K47/36 ,  A61K47/38 ,  A61P27/16 ,  C07B2200/13 ,  C07D223/18

Abstract: The present disclosure provides crystalline Compound I and crystalline Compound II, pharmaceutical compositions comprising one of said crystalline compounds suitable for intratympanic administration, and methods for treating otic disorders using the crystalline compounds and the pharmaceutical compositions.

公开(公告)号：EP3366290A1

公开(公告)日：2018-08-29

申请号：EP18157637.2

申请日：2018-02-20

Applicant: MONTERO GIDA SANAYI VE TICARET A.S.

Inventor： TÜRKYILMAZ, Ali ,  PEHLIVAN AKALIN, Nur ,  KARACA, Gizem

IPC: A61K31/381 ,  A61K31/4415 ,  A61K31/51 ,  A61K31/714 ,  A61K47/02 ,  A61K47/22 ,  A61K47/24 ,  A61K47/36 ,  A61K47/38 ,  A61K9/00 ,  A61K9/20

CPC classification number: A61K31/381 ,  A61K9/0053 ,  A61K9/209 ,  A61K9/2095 ,  A61K9/2866 ,  A61K31/385 ,  A61K31/4415 ,  A61K31/51 ,  A61K31/714 ,  A61K47/38 ,  A61K2300/00

Abstract: The present invention relates to pharmaceutical compositions comprising alpha lipoic acid or a pharmaceutically acceptable salt thereof in combination with at least one watersoluble vitamin or pharmaceutically acceptable salts thereof.

公开(公告)号：EP3362062A1

公开(公告)日：2018-08-22

申请号：EP16855992.0

申请日：2016-10-07

Applicant: Hennepin Life Sciences, LLC

Inventor： SCHLIEVERT, Patrick M. ,  PETERSON, Marnie L.

IPC: A61K31/23 ,  A61K47/14 ,  A61K47/44 ,  A61K9/06

CPC classification number: A61K31/23 ,  A61K9/06 ,  A61K45/06 ,  A61K47/10 ,  A61K47/12 ,  A61K47/14 ,  A61K47/183 ,  A61K47/38 ,  A61K47/44 ,  A61K2300/00 ,  A61L29/005 ,  A61L29/085 ,  A61L29/16 ,  A61L2300/22 ,  A61L2300/404 ,  A61M25/0017 ,  A61P31/04 ,  C08L23/06 ,  C08L23/12 ,  C08L1/26

Abstract: This invention relates to treating and preventing urinary tract infections. Glycerol monolaurate (GML) and/or GML-related compositions together with suitable accelerants in gel-based formulation may be used to treat urinary tract infections that may be generally diagnosed, for example, in women, catheterized patients and elderly individuals. Such a gel-based formulation kills, or inhibits the growth of, one or more pathogenic microorganisms that cause urinary tract infections.

公开(公告)号：EP3212674B1

公开(公告)日：2018-08-22

申请号：EP15791420.1

申请日：2015-10-21

Applicant: Dow Global Technologies LLC

Inventor： PETERMANN, Oliver ,  SPREHE, Matthias

IPC: C08B13/00 ,  C08L1/32 ,  A61K47/38 ,  C09D101/32

CPC classification number: C08B13/00 ,  A61K9/2866 ,  A61K47/38 ,  C08L1/32 ,  C09D101/32

Abstract: A process for producing an esterified cellulose ether comprises the step of reacting a cellulose ether with an aliphatic monocarboxylic acid anhydride and/or a dicarboxylic acid anhydride and with a depolymerizing agent, wherein the cellulose ether has an initial viscosity of at least 500 mPa·s, measured as a 2 weight-% solution in water at 20° C., and the reaction of the cellulose ether with the aliphatic monocarboxylic acid anhydride and/or the dicarboxylic acid anhydride and with the depolymerizing agent is conducted simultaneously or in sequence in one reaction device.

公开(公告)号：EP3360533A1

公开(公告)日：2018-08-15

申请号：EP16853815.5

申请日：2016-08-30

Applicant: LG Household & Health Care Ltd.

Inventor： KIM, Jong-Hoon ,  AHN, Jae-Hyun ,  OH, Kwang-Ho ,  LEE, In-Ho ,  SHIM, Woo-Sun

IPC: A61K8/02 ,  A61K8/22 ,  A61K8/24 ,  A61K8/19 ,  A61K8/97 ,  A61K9/70 ,  A61K47/38 ,  A61K9/00 ,  A61Q11/02 ,  A61K8/72

CPC classification number: A61K8/0208 ,  A61K8/02 ,  A61K8/19 ,  A61K8/22 ,  A61K8/24 ,  A61K8/34 ,  A61K8/345 ,  A61K8/4973 ,  A61K8/72 ,  A61K8/73 ,  A61K8/731 ,  A61K8/8176 ,  A61K8/922 ,  A61K8/97 ,  A61K9/00 ,  A61K9/0056 ,  A61K9/0063 ,  A61K9/70 ,  A61K9/7007 ,  A61K47/38 ,  A61K2800/92 ,  A61Q11/00 ,  A61Q11/02

Abstract: The present invention provides a patch for attaching to teeth or a surrounding part of teeth, and the patch can be easily removed by tooth brushing alone.

公开(公告)号：EP3272345A4

公开(公告)日：2018-08-01

申请号：EP16765092

申请日：2016-03-17

Applicant: DAIICHI SANKYO CO LTD

Inventor： TAJIRI SHINICHIRO ,  HISAZUMI JIN ,  YOSHINAGA SHINJI ,  FUJIMORI HIROYUKI ,  ARAI HIROAKI

IPC: A61K31/195 ,  A61K9/20 ,  A61K47/10 ,  A61K47/12 ,  A61K47/14 ,  A61K47/22 ,  A61K47/24 ,  A61K47/26 ,  A61K47/36 ,  A61K47/38 ,  A61K47/40 ,  A61P25/00 ,  A61P25/04 ,  A61P29/00

CPC classification number: A61K31/195 ,  A61K9/20 ,  A61K9/2013 ,  A61K9/2018 ,  A61K9/2054 ,  A61K9/2095 ,  A61K9/28 ,  A61K47/10 ,  A61K47/12 ,  A61K47/14 ,  A61K47/22 ,  A61K47/24 ,  A61K47/26 ,  A61K47/36 ,  A61K47/38 ,  A61K47/40

Abstract: An object of the present invention is to provide [(1R,5S,6S)-6-(aminomethyl)-3-ethylbicyclo[3.2.0]hept-3-en-6-yl]acetic acid monobenzenesulfonate as a stabilized pharmaceutical solid preparation, and also to provide a method for preparing the stabilized pharmaceutical solid preparation. The object can be attained by a pharmaceutical solid preparation comprising [(1R,5S,6S)-6-(aminomethyl)-3-ethylbicyclo[3.2.0]hept-3-en-6-yl]acetic acid monobenzenesulfonate which is compound represented by the following formula (I) in combination with (i) one or two or more excipients, (ii) one or two or more disintegrants, and (iii) a specific antioxidant.

公开(公告)号：EP3257512A4

公开(公告)日：2018-07-25

申请号：EP16749300

申请日：2016-02-12

Applicant: MARUHO KK

Inventor： FUJIKAWA AKIRA ,  YAMADA HIROSHI

IPC: A61K9/06 ,  A61K31/4709 ,  A61K47/10 ,  A61K47/38 ,  A61P17/10

CPC classification number: A61K31/4709 ,  A61K9/0014 ,  A61K9/06 ,  A61K47/10 ,  A61K47/38 ,  A61P17/10

Abstract: The purpose of the present invention is to provide an external preparation which exerts a therapeutic and/or prophylactic effect on infectious diseases in the field of dermatology such as acne accompanied by suppurative inflammation or epidermal skin infectious diseases when administered once a day mainly to a human patient. As an example of the external preparation according to the present invention, an external preparation, which is characterized by comprising as an active ingredient 1-cyclopropyl-8-methyl-7-[5-methyl-6-(methylamino)-3-pyridyl]-4-oxo-1,4-dihydro-3-quinolincarboxylic acid and/or a pharmaceutically acceptable salt thereof and exerting a therapeutic and/or prophylactic effect on infectious diseases in the field of dermatology when administered once a day to a human patient, can be cited.

公开(公告)号：EP3248595A4

公开(公告)日：2018-07-11

申请号：EP16740249

申请日：2016-01-21

Applicant: NIPRO CORP

Inventor： SHINKAI NORIHIRO ,  KAWAMURA NAOHISA ,  SHIRAISHI HIROAKI ,  HAYASHIDA TOMOHIRO

IPC: A61K9/70 ,  A61K9/00 ,  A61K9/50 ,  A61K31/137 ,  A61K47/36 ,  A61K47/38

CPC classification number: A61K9/7007 ,  A61K9/0056 ,  A61K9/5047 ,  A61K9/5078 ,  A61K31/137 ,  A61K47/32 ,  A61K47/34 ,  A61K47/38

Abstract: The present invention addresses the problem of providing a film preparation that enables large quantities of medicinal products to be blended thereinto. The present invention provides a film preparation that contains a film base material, which contains a water-soluble polymer, and medicinal product-containing particles, which are supported on the film base material and which have a coating layer containing a hydrophobic coating agent on the outermost surface of the particles. The content of the medicinal product in the medicinal product-containing particles may be 0.1-95 mass% relative to the overall film preparation. The water-soluble polymer may include one or more types selected from the group consisting of hydroxypropyl cellulose, hydroxypropylmethyl cellulose and pullulan.