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公开(公告)号：EP4243928A1
公开(公告)日：2023-09-20
申请号：EP21801956.0
申请日：2021-11-10
IPC分类号： A61P3/04 , A61P35/00 , C07K16/22 , A61K39/395
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公开(公告)号：EP4187292A1
公开(公告)日：2023-05-31
申请号：EP21210527.4
申请日：2021-11-25
发明人： Hecht, Bert , Wu, Xiaofei , Ehehalt, Raphael
摘要： The present invention relates to a nanodrone, a method of operating a nanodrone, and a system for operating a nanodrone. The nanodrone comprises a substrate extending perpendicular to a normal direction and two or more nanoantennas arranged on and/or in the substrate. Each of the two or more nanoantennas exhibits an optically addressable resonance at a respective resonance wavelength. The two or more nanoantennas comprise a first nanoantenna and a second nanoantenna, each being configured to scatter circularly polarized light at the respective resonance wavelength that is incident on the nanoantenna along the normal direction such that photons of the scattered light have a mean wavevector k i,L and k i,R in a plane perpendicular to the normal direction for left- and right-circularly polarized light, respectively, with i = 1 for the first nanoantenna and i = 2 for the second nanoantenna. The mean wavevector k i,j i with j i = L or R is non-zero. The mean wavevector k i, j i with J i = L for j i = R and J i = R for j i = L is substantially zero or substantially anti-parallel to k i,j i . At least one of k 1, L and k 1, R is substantially parallel or substantially anti-parallel to one of k 2, L and k 2, R .
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公开(公告)号：EP4045006A1
公开(公告)日：2022-08-24
申请号：EP20793297.1
申请日：2020-10-13
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公开(公告)号：EP3838322A1
公开(公告)日：2021-06-23
申请号：EP19218923.1
申请日：2019-12-20
发明人： GÖBEL, Lothar
IPC分类号： A61M16/04
摘要： The invention relates to a sealing cuff (200) for a tracheal tube and a tracheal ventilation device. The sealing cuff comprises an expandable body (102) that is configured to be expanded from a collapsed state to an expanded state. The expandable body comprises an axial opening (104) that extends through the expandable body along an axial direction and is configured to receive a tracheal tube. The expandable body comprises a proximal portion (106), a center portion (108) and a distal portion (110) that are arranged along the axial direction and surround the axial opening. The proximal portion comprises a radially constricted portion (106B) adjacent to the center portion. A radial extent w 2 of the radially constricted portion perpendicular to the axial direction is less than 75% of a radial extent w 1 of the proximal portion and less than 75% of a radial extent w 3 of the center portion in the expanded state. The distal portion comprises a radially constricted portion (110B) adjacent to the center portion. A radial extent w 4 of the radially constricted portion perpendicular to the axial direction is less than 75% of a radial extent w 5 of the distal portion and less than 75% of the radial extent w 3 of the center portion in the expanded state.
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公开(公告)号：EP3808351A1
公开(公告)日：2021-04-21
申请号：EP19203033.6
申请日：2019-10-14
IPC分类号： A61K31/555 , A61K33/04 , A61K33/24 , A61K33/26 , A61K33/32 , A61K33/40 , A61K9/48 , A61K9/00 , A61K9/51 , A61P1/00 , A61P1/04 , A61P29/02 , A01N1/02
摘要： The present invention discloses a therapeutic gas release system for oral administration comprising a therapeutic gas releasing compound A, and a therapeutic gas release triggering compound B, wherein compound A and B are separated from each other by an inner septum during storage of the system, wherein compound A and B are surrounded by an outer membrane, which is a gas-permeable and water- and solid-impermeable membrane, preferably a silicone membrane, and wherein therapeutic gas release from the system is activated before oral administration by breaking the inner septum . The system of the present invention is suitable for the treatment of (inflammatory) diseases of the gastrointestinal tract.
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公开(公告)号：EP3774021A1
公开(公告)日：2021-02-17
申请号：EP19719165.3
申请日：2019-04-02
申请人： FRAUNHOFER-GESELLSCHAFT zur Förderung der angewandten Forschung e.V. , Julius-Maximilians-Universität Würzburg
发明人： REHM, Thomas , KRÜGER, Anke
IPC分类号： B01J19/12
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67.发明公开
公开(公告)号：EP3686670A1
公开(公告)日：2020-07-29
申请号：EP19153630.9
申请日：2019-01-24
发明人： Krauss, Enno , Hecht, Bert , Le, Thien Anh , Maaß, Henriette
摘要： Provided is a method and an apparatus of manufacturing nano-structures by cutting out portions of a material layer and removing the cut-out portions.
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68.发明公开
公开(公告)号：EP3569614A1
公开(公告)日：2019-11-20
申请号：EP18173245.4
申请日：2018-05-18
发明人： MEINEL, Lorenz , LÜHMANN, Tessa , BRAUN, Alexandra
IPC分类号： C07K14/65 , A61K38/30 , C12N9/10 , A61K38/18 , C07K14/475
摘要： The present invention relates to compounds and their use in the treatment of lesions, in tissue regeneration and/or tissue engineering. The compounds act as substrates for enzymes having transglutaminase activity and are suitable for their immobilization and/or attached therapeutic or diagnostic molecules on extracellular matrix (ECM) or synthetic ECM-derived materials, in particular for the immobilization of myostatin inhibitors.
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公开(公告)号：EP3561045A1
公开(公告)日：2019-10-30
申请号：EP19170636.5
申请日：2019-04-23
申请人： Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. , Julius-Maximilians-Universität Würzburg
摘要： Die vorliegende Erfindung betrifft ein Verfahren zur Kultivierung von Zellen auf einem Zellkultursubstrat, wobei das Zellkultursubstrat ein Zellkultursubstrat aus Glas umfasst und mindestens ein Teil des Zellkultursubstrats aus Glas eine nanoporös strukturierte Oberfläche mit einem durchschnittlichen Porendurchmesser von 2 bis 150 nm aufweist, und die Verwendung eines Zellkultursubstrats zur Kultivierung oder Differenzierung von Zellen, als Boden eines Zellkulturgefäßes oder Bioreaktors, als herausnehmbarer Einsatz für Zellkulturgefäße oder Bioreaktoren und/oder als perfusive Membran für 3D-Zellkultur-Reaktoren, wobei das Zellkultursubstrat ein Zellkultursubstrat aus Glas umfasst und mindestens ein Teil des Zellkultursubstrats aus Glas eine nanoporös strukturierte Oberfläche mit einem durchschnittlichen Porendurchmesser von 2 bis 150 nm aufweist.
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