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公开(公告)号：EP3623386A1
公开(公告)日：2020-03-18
申请号：EP19194817.3
申请日：2016-01-08
申请人： BioNTech SE , Genmab A/S
摘要： The present invention relates to binding agents binding to receptors of the TNF superfamily, in particular binding agents binding to at least two different receptors of the TNF superfamily, as well as to their use in medicine. The present invention further relates to nucleic acid molecules encoding such binding agents, to cells comprising such nucleic acid molecules and to pharmaceutical compositions and kits.
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公开(公告)号：EP3571296A1
公开(公告)日：2019-11-27
申请号：EP18701425.3
申请日：2018-01-17
申请人： Biontech SE , University Of Verona
IPC分类号： C12N5/0786 , A61K35/15 , A61K35/28 , C07K14/435 , C12N5/0775 , A61K48/00 , A61K35/12
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公开(公告)号：EP4411376A2
公开(公告)日：2024-08-07
申请号：EP24171718.0
申请日：2017-05-10
申请人： BioNTech SE , TRON - Translationale Onkologie an der Universitätsmedizin der Johannes Gutenberg- Universität Mainz gemeinnützige GmbH
IPC分类号： G01N33/53
CPC分类号： G01N33/5308 , G01N33/6878 , G01N33/6887 , G01N2333/471220130101 , G01N2800/5220130101 , G01N33/5035 , A61P35/04
摘要： The present invention relates to methods for predicting peptides or polypeptides such as T cell epitopes useful for immunotherapy such as for vaccination. In particular, the present invention relates to methods for predicting whether peptides or polypeptides such as tumor-associated antigens or epitopes, in particular tumor-associated neoantigens or neoepitopes, are immunogenic and, in particular, useful for immunotherapy such as for vaccination. The methods of the invention may be used, in particular, for the provision of vaccines which are specific for a patient's tumor and, thus, in the context of personalized cancer vaccines.
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公开(公告)号：EP4295862A2
公开(公告)日：2023-12-27
申请号：EP23181557.2
申请日：2023-06-26
申请人： BioNTech SE
发明人： MUIK, Alexander , PORAN, Asaf , SAHIN, Ugur , SWANSON, Kena Anne , YANG, Qi , CAI, Hui , MODJARRAD, Kayvon
摘要： This disclosure relates to the field of RNA to prevent or treat coronavirus infection. In particular, the present disclosure relates to methods and agents for vaccination against coronavirus infection and inducing effective coronavirus antigen-specific immune responses such as antibody and/or T cell responses.
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公开(公告)号：EP4139616A1
公开(公告)日：2023-03-01
申请号：EP21718593.3
申请日：2021-04-16
申请人： Pfizer Inc. , BioNTech SE
发明人： NAUTA, Marjoh , PEETERS, Dirk Jozef , VAN DOORSLAER, Tom Frank Steven , BADKAR, Advait Vijay , DARVARI, Ramin , WARNE, Nicholas William , JEAN, James , HENDRIKSE, Danny Pierre G. , SAHIN, Ugur , GÜLER, Alptekin , KUHN, Andreas , MUIK, Alexander , VOGEL, Annette , WALZER, Kerstin , WITZEL, Sonja , HEIN, Stephanie , TÜRECI, Özlem
IPC分类号： F25D3/12 , A61K39/215 , A61K45/06 , B65D81/18 , C12N15/00
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公开(公告)号：EP4121104A2
公开(公告)日：2023-01-25
申请号：EP21772515.9
申请日：2021-03-19
申请人： BioNTech SE
发明人： GAYNOR, Richard B. , SRINIVASAN, Lakshmi , PORAN, Asaf , HARJANTO, Dewi , KUKSIN, Christina , ROTHENBERG, Daniel Abram , SROUJI, John , SAHIN, Ugur
IPC分类号： A61K39/12 , A61K39/215 , C07K14/165 , C07K7/06 , A61P31/14
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公开(公告)号：EP4100059A1
公开(公告)日：2022-12-14
申请号：EP21704444.5
申请日：2021-02-04
申请人： Genmab A/S , BioNTech SE
发明人： SAHIN, Ugur , MUIK, Alexander , ALTINTAS, Isil , FORSSMANN, Ulf , SASSER, Kate , JURE-KUNKEL, Maria, N. , GUPTA, Manish
IPC分类号： A61K39/395 , A61P35/00 , C07K16/28 , C07K16/46
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公开(公告)号：EP4071176A3
公开(公告)日：2022-12-14
申请号：EP22167212.4
申请日：2016-01-08
申请人： BioNTech SE , Genmab A/S
摘要： The present invention relates to binding agents binding to receptors of the TNF superfamily, in particular binding agents binding to at least two different receptors of the TNF superfamily, as well as to their use in medicine. The present invention further relates to nucleic acid molecules encoding such binding agents, to cells comprising such nucleic acid molecules and to pharmaceutical compositions and kits.
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69.发明公开
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公开(公告)号：EP4034149A1
公开(公告)日：2022-08-03
申请号：EP20772086.3
申请日：2020-09-22
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